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Table 8.8

Cancer of the Esophagus (Invasive)

5-Year Relative Survival (Percent) by Year of Diagnosis
Year of
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
1960-1963a - - - 4 4 6 1 0 2
1970-1973a - - - 4 4 4 4 4 3
1975-1977b 5.0 4.0 7.5 5.5 4.8 7.0 3.5 2.0 7.7
1978-1980b 5.0 4.8 5.6 5.3 5.3 5.2 4.3 3.4 6.8
1981-1983b 6.6 6.0 8.2 7.3 6.5 9.0 4.3 3.7 6.5
1984-1986b 9.5 8.4 12.1 10.2 9.0 13.0 8.7 8.2 9.9
1987-1989b 9.4 9.4 9.5 10.5 11.0 9.2 6.6 5.3 10.2
1990-1992b 12.1 11.7 13.4 12.9 12.3 14.8 9.1 9.4 8.4
1993-1995b 12.1 12.2 11.7 13.4 13.6 12.7 7.6 7.8 6.9
1996-1998b 13.4 13.0 14.4 14.1 13.9 14.7 10.2 8.5 13.6
1999-2001b 18.1 17.6 19.6 18.8 18.6 19.8 12.5 10.6 16.3
2002-2005b 18.3 18.0 19.3 19.4 19.2 19.8 12.9 11.2 16.0
2006-2012b 20.5f 20.5f 20.7f 21.7f 21.8f 21.2f 12.5f 10.5f 16.3f
5-Year Period Survival (Percent)cd
Year All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
2012 18.6 18.3 19.6 19.3 19.2 19.7 12.0 9.6 16.5
Stage Distribution (%) 2006-2012ce, Case Counts and Percentages
Stage at
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
Number of cases 20,995 16,572 4,423 17,533 14,112 3,421 2,272 1,564 708
Percent 100% 100% 100% 100% 100% 100% 100% 100% 100%
Localized 20 19 23 20 20 23 18 17 21
Regional 31 31 29 31 31 29 31 31 32
Distant 38 40 32 38 40 32 40 41 35
Unstaged 11 10 16 10 9 16 11 11 12
5-Year Relative Survival (Percent) 2006-2012c by Age at Diagnosis
Age at
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
Ages <45 19.6 21.5 7.9 20.2 22.2 6.3 11.3 8.2 12.4g
Ages 45-54 20.5 19.6 24.6 22.3 21.0 29.5 10.9 10.8 11.6
Ages 55-64 20.3 19.4 25.0 21.5 20.9 25.2 12.7 9.3 22.7
Ages 65-74 21.3 21.3 21.4 22.3 22.4 22.3 12.5 11.7 13.3
Ages 75+ 11.5 11.7 11.2 11.7 12.0 11.1 9.2 9.2 8.7
Ages <65 20.3 19.6 23.9 21.6 21.0 25.4 12.1 9.7 18.1
Ages 65+ 16.6 17.1 15.2 17.2 17.8 15.3 11.1 10.9 11.1
5-Year Relative Survival (Percent) 2006-2012c by Stage at Diagnosise
Stage at
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
All Stages 18.4 18.3 18.5 19.2 19.3 18.8 11.7 10.1 15.0
Localized 41.3 43.8 33.4 43.6 46.1 34.6 22.4 20.8 24.0
Regional 22.8 22.4 24.3 23.5 23.3 24.6 16.6 15.6 19.1
Distant 4.5 4.2 5.9 4.6 4.4 5.5 3.6 1.8 8.1
Unstaged 12.4 12.6 12.0 12.4 12.8 11.4 9.7 9.6 10.6

Footnotes:

a Based on End Results data from a series of hospital registries and one population-based registry.

b SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta). Based on follow-up of patients into 2013.

c SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey and Georgia excluding ATL/RG). Based on follow-up of patients into 2013.

d Period survival provides a 2012 estimate of survival by piecing together the most recent conditional survival estimates from several cohorts. It is computed here using three year calendar blocks (2010-2012: 0-1 year survival), (2009-2011: 1-2 year survival), (2008-2010: 2-3 year survival), (2007-2009: 3-4 year survival), (2006-2008: 4-5 years survival).

e Stage at diagnosis is classified using SEER Summary Stage 2000. Stage distribution percentages may not sum to 100 due to rounding.

f The difference between 1975-1977 and 2006-2012 is statistically significant (p<.05).

g The standard error is between 5 and 10 percentage points.

h The standard error is greater than 10 percentage points.

- Statistic could not be calculated due to fewer than 25 cases during the time period.

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