SEER Inquiry System - View
Source 1: 2012 Heme & Lymph Manual & DB
Primary site--Heme & Lymphoid Neoplasms: How is the primary site coded for a 2011 diagnosis of systemic mastocytosis?
The 2012 Hematopoietic and Lymphoid Database states the primary site for systemic mastocytosis is C421 [bone marrow], however, the 2010 Hematopoietic Database does not give a primary site for this histology. Patient presented with leukopenia, anemia and monoclonal gammopathy. A bone marrow biopsy in 2011 showed systemic mastocytosis [9741/3]. A subsequent shave biopsy of abdominal skin showed histologic features that were consistent with a diagnosis of mastocytosis. A later bone marrow biopsy was subsequently performed that showed progressive systemic mastocytosis.
NOTE: The 2010 Hematopoietic Database used for cases diagnosed 2010 and 2011 did not give clear instructions about coding the primary site for this histology. Use the 2012 Hematopoietic Database for further clarification on coding the primary site for 2010-2011 diagnoses of systemic mastocytosis [9741/3].
For cases diagnosed 2010 and later, access the Hematopoietic Database at
Click on Hematopoietic Project. Click on Hematopoietic and Lymphoid Database. The 2012 Hematopoietic Coding Manual (PDF) button will appear to indicate the correct version of the program is available now for query.
The primary site is coded to the bone marrow [C42.1] for systemic mastocytosis with bone marrow involvement diagnosed prior to 2012. The steps used to arrive at this decision are:
Step 1: Enter in the Heme DB to find the histology. Click on the SEARCH button. Ensure that the term "systemic mastocytosis" [9741/3] is highlighted on the screen. systemic mastocytosis
Step 2: Check the PRIMARY SITE(S) section. The Hematopoietic Database indicates the primary site for systemic mastocytosis is always coded to bone marrow [C42.1].