Help me code for diagnosis year :
PV arises in clonal hematopoietic stem cell, characterized by increased RBC production independent of mechanisms that normally regulate erythropoiesis.
The blood and bone marrow are the primary sites of involvement. The physician also correlates the morphologic findings in BM biopsy with other clinical and laboratory findings to firmly establish the diagnosis.
Treatment is used for control, not cure. The patient has phlebotomy (removal of blood, usually a pint every other day) until the hematocrit reaches a normal level. Then blood is removed every few months as needed.
There are three phases of Polycythemia Vera:
1. Prodromal, pre-polycythemia phase
2. Overt polycythemia phase
3. Spent or post-polycythemia myelofibrosis phase
The "spent phase" of polycythemia vera is the finding of myelofibrosis in the bone marrow. The myelofibrosis is a result of the PV. This is still the same primary, polycythemia vera, with the bone marrow showing the effect of the disease. This form of myelofibrosis is different from primary myelofibrosis, which is code 9961/3.
The diagnosis of "polycythemia" by itself is not reportable. To be reportable the diagnosis must be polycythemia vera, or some of the other alternate names listed above in the alternate names section.
Aspirin was previously documented as treatment for MPN, NOS. This was found to be incorrect. Treatment has been updated based on the NCI website. Aspirin is given to patients with PV to reduce bone pain. The aspirin is not used to manage the cancer. Treatment has been updated based on the NCI website (updated 6/12/15).