This neoplasm is not reportable EXCEPT for Brain and CNS Sites.
Name
Polymorphic post-transplant lymphoproliferative disorder
ICD-O-3 Morphology
9971/1: Polymorphic Post Transplant Lymphoproliferative Disorder (PTLD)
Effective
2021 and later
Reportability
This neoplasm is not reportable EXCEPT for Brain and CNS Sites
Primary Site(s)
See Abstractor Notes
This neoplasm is reportable for primary sites C700-C729, C751-C753 only.
Abstractor Notes
Per the IARC/WHO Committee for ICD-O and included in the WHO Tumors of Hematopoietic and Lymphoid Tissues, Revised 4th Ed, Volume 2, PTLD by itself is now a /1. This change will go into effect for 2021+.
PTLD by itself will continue to be reportable for cases diagnosed 2010-2020 (See 9971/3).
PTLD by itself will continue to be reportable for cases diagnosed 2010-2020 (See 9971/3).
Alternate Names
Early PTLD
Florid follicular hyperplasia
Infectious mononucleosis-like lesion
Infectious mononucleosis-like PTLD
Polymorphic B-cell PTLD
Polymorphic post transplant lymphoproliferative disorders
Polymorphic PTLD
P-PTLD
PTLD, NOS
Definition
Post-transplant lymphoproliferative disorders (PTLD) are lymphoid or plasmacytic proliferations that develop as a consequence of immunosuppression in a recipient of a solid organ, bone marrow, or stem cell allograft. The early lesions are defined as lymphoid proliferations in an allograft recipient, characterized by architectual preservation of the involved tissue, with preservation of the nodular sinuses or tonsillar crypts, and residual or sometimes floridly reactive follicles in some cases.
Corresponding ICD-9 Codes
238.77 Post-transplant lymphoproliferative disorder (PTLD)
Corresponding ICD-10 Codes
D47.7 Other specified neoplasms of uncertain or unknown behavior of lymphoid, hematopoietic, and related tissue
Corresponding ICD-10-CM Codes (U.S. only)
D47.Z1 Post-transplant lymphoproliferative disorder (PTLD) (effective October 01, 2015)
Sources
International Classification of Diseases for Oncology, Third Edition, Second Revision. Geneva: World Health Organization, 2020.
Section: ICD-O-3.2 (2020) Morphological Codes
Pages: http://www.iacr.com.fr/index.php?option=com_content&view=category&layout=blog&id=100&Itemid=577
Section: ICD-O-3.2 (2020) Morphological Codes
Pages: http://www.iacr.com.fr/index.php?option=com_content&view=category&layout=blog&id=100&Itemid=577