B lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1)

Name
B lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1)
ICD-O-3 Morphology
9818/3
Effective 2010 and later
Reportable
for cases diagnosed 2010 and later
Primary Site(s)
See Abstractor Notes and Module 4: Rules PH7, PH8

Help me code for dx year :

Grade
6 - B-cell
Module Rule
Module 4: PH7, PH8
Alternate Names
None
Definition
This is a neoplasm of lymphoblasts committed to the B lineage with a t(1;19) translocation between the E2A(TCF3) gene on chromosome 19 and the PBX1 gene on chromosome 1. This leukemia is relatively common in children, although present in adults as well.
Abstractor Notes
(This code is effective for cases diagnosed 2010 and later. For cases diagnosed prior to 2010 see codes: 9728/3 [lymphomas] or 9836/3 [leukemia].) This neoplasm is relatively common in children accounting for about 6% of cases of B-ALL although adults are also affected.
Definitive Diagnostic Methods
Bone marrow biopsy
Genetics testing
Immunophenotyping
Genetics Data
E2A-PBX1 translocation
Immunophenotyping
CD9+
CD10+ cytoplasmic heavy chain-positive pre-B-cell phenotype
CD19+
CD34-
Treatments
Chemotherapy
Stem cell transplant
Transformations to
No Transformations
Transformations from
No Transformations
Corresponding ICD-9 Codes
204.8 Other lymphoid leukemia
Corresponding ICD-10 Codes
C91.7 Other lymphoid leukemia
Corresponding ICD-10-CM Codes (effective October 1, 2015 U.S. only)
C91.Z Other lymphoid leukemia
Signs and Symptoms
None
Diagnostic Exams
None
Recurrence and Metastases
None
Epidemiology and Mortality
None