SEER is an authoritative source of information on cancer incidence and survival in the United States. SEER currently collects and publishes cancer incidence and survival data from population-based cancer registries covering approximately 28 percent of the U.S. population.
This neoplasm is committed to the B-cell lineage in which the blasts harbour a translocation between the BCR gene on chromosome 22 and the ABL1 oncogene on chromosome 9. Presenting factors include increased WBC, but there are otherwise no characteristic clinical findings. Patients with B-ALL may have organ involvement, but lymphomatous presentations are rare.
(This code is effective for cases diagnosed 2010 and later. For cases diagnosed prior to 2010 see codes: 9728/3 [lymphomas] or 9836/3 [leukemia].) This disease occurs in both children and adults. Children usually have a better outcome. This neoplasm is confirmed by immunological markers and/or ultrastructural cytochemistry. Patients present with evidence of BM failure with anemia, thrombocytopenia and neutropenia. Patients with t(9;22) B-ALL may have organ involvement, however lymphomatous presentations are rare.