SEER Stat Fact Sheets: Oral Cavity and Pharynx Cancer

Statistics at a GlanceShow More

At a Glance

  • Estimated New Cases in 2016 48,330
  • % of All New Cancer Cases2.9%
  • Estimated Deaths in 2016 9,570
  • % of All
    Cancer Deaths
    1.6%

Percent Surviving
5 Years

64.0% 2006-2012

Number of New Cases and Deaths per 100,000: The number of new cases of oral cavity and pharynx cancer was 11.1 per 100,000 men and women per year. The number of deaths was 2.4 per 100,000 men and women per year. These rates are age-adjusted and based on 2009-2013 cases and deaths.

Lifetime Risk of Developing Cancer: Approximately 1.1 percent of men and women will be diagnosed with oral cavity and pharynx cancer at some point during their lifetime, based on 2011-2013 data.

Prevalence of This Cancer: In 2013, there were an estimated 300,682 people living with oral cavity and pharynx cancer in the United States.

Survival StatisticsShow More

How Many People Survive 5 Years Or More after Being Diagnosed with Oral Cavity and Pharynx Cancer?

Relative survival statistics compare the survival of patients diagnosed with cancer with the survival of people in the general population who are the same age, race, and sex and who have not been diagnosed with cancer. Because survival statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to treatment can vary greatly.

64.0%

Percent Surviving
5 Years

64.0%

Based on data from SEER 18 2006-2012. Gray figures represent those who have died from oral cavity and pharynx cancer. Green figures represent those who have survived 5 years or more.

Additional Information

Cancer stage at diagnosis, which refers to extent of a cancer in the body, determines treatment options and has a strong influence on the length of survival. In general, if the cancer is found only in the part of the body where it started it is localized (sometimes referred to as stage 1). If it has spread to a different part of the body, the stage is regional or distant. The earlier oral cavity and pharynx cancer is caught, the better chance a person has of surviving five years after being diagnosed. For oral cavity and pharynx cancer, 30.2% are diagnosed at the local stage. The 5-year survival for localized oral cavity and pharynx cancer is 83.3%.

Percent of Cases & 5-Year Relative Survival by Stage at Diagnosis: Oral Cavity and Pharynx Cancer
Percent of Cases by Stage
  • Localized (30%)
    Confined to Primary Site
  • Regional (47%)
    Spread to Regional Lymph Nodes
  • Distant (18%)
    Cancer Has Metastasized
  • Unknown (5%)
    Unstaged
30% localized; 47% regional; 18% distant; 5% unknown
5-Year Relative Survival
83.3% localized; 63.3% regional; 38.0% distant; 47.2% unstaged

SEER 18 2006-2012, All Races, Both Sexes by SEER Summary Stage 2000

Additional Information

Number of New Cases and DeathsShow More

How Common Is This Cancer?

Common Types of Cancer Estimated New
Cases 2016
Estimated
Deaths 2016
1. Breast Cancer (Female) 246,660 40,450
2. Lung and Bronchus Cancer 224,390 158,080
3. Prostate Cancer 180,890 26,120
4. Colon and Rectum Cancer 134,490 49,190
5. Bladder Cancer 76,960 16,390
6. Melanoma of the Skin 76,380 10,130
7. Non-Hodgkin Lymphoma 72,580 20,150
8. Thyroid Cancer 64,300 1,980
9. Kidney and Renal Pelvis Cancer 62,700 14,240
10. Leukemia 60,140 24,400
- - -
Oral Cavity and Pharynx Cancer 48,330 9,570

Oral cavity and pharynx cancer represents 2.9% of all new cancer cases in the U.S.

2.9%

In 2016, it is estimated that there will be 48,330 new cases of oral cavity and pharynx cancer and an estimated 9,570 people will die of this disease.

Oral cancer is more common in men than women, among those with a history of tobacco or heavy alcohol use, and individuals infected with human papillomavirus (HPV). The number of new cases of oral cavity and pharynx cancer was 11.1 per 100,000 men and women per year based on 2009-2013 cases.

Percent of New Cases by Age Group: Oral Cavity and Pharynx Cancer
0.5% under 20; 2.0% 20-34; 5.1% 35-44; 18.8% 45-54; 30.5% 55-64; 22.9% 65-74; 14.0% 75-84; 6.1% 85 and older

Oral cavity and pharynx cancer is most frequently diagnosed among people aged 55-64.

Median Age
At Diagnosis

62

SEER 18 2009-2013, All Races, Both Sexes

Number of New Cases per 100,000 Persons by Race/Ethnicity & Sex: Oral Cavity and Pharynx Cancer
MalesFemales
  • Male 16.7All RacesFemale 6.2
  • Male 17.4WhiteFemale 6.4
  • Male 14.4BlackFemale 5.2
  • Male 11.1Asian /
    Pacific Islander
    Female 4.9
  • Male 13.2American Indian /
    Alaska Native
    Female 5.7
  • Male 10.0HispanicFemale 4.0
  • Male 17.8Non-HispanicFemale 6.6

SEER 18 2009-2013, Age-Adjusted

For oral cancer, death rates are higher among males, particularly those of African American descent. The number of deaths was 2.4 per 100,000 men and women per year based on 2009-2013 deaths.

Percent of Deaths by Age Group: Oral Cavity and Pharynx Cancer
0.1% under 20; 0.8% 20-34; 2.4% 35-44; 13.1% 45-54; 26.4% 55-64; 24.6% 65-74; 20.3% 75-84; 12.3% 85 and older

The percent of oral cavity and pharynx cancer deaths is highest among people aged 55-64.

Median Age
At Death

67

U.S. 2009-2013, All Races, Both Sexes

Number of Deaths per 100,000 Persons by Race/Ethnicity & Sex: Oral Cavity and Pharynx Cancer
MalesFemales
  • Male 3.8All RacesFemale 1.3
  • Male 3.7WhiteFemale 1.3
  • Male 5.0BlackFemale 1.3
  • Male 2.9Asian /
    Pacific Islander
    Female 1.2
  • Male 3.3American Indian /
    Alaska Native
    Female 1.1
  • Male 2.4HispanicFemale 0.8
  • Male 3.9Non-HispanicFemale 1.4

U.S. 2009-2013, Age-Adjusted

Trends in RatesShow More

Changes Over Time

Keeping track of the number of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments.

Using statistical models for analysis, rates for new oral cavity and pharynx cancer cases have been rising on average 0.6% each year over the last 10 years. Death rates have not changed significantly over 2004-2013. 5-year survival trends are shown below the figure.

More About This CancerShow More

Cancer and the Oral Cavity and Pharynx

Anatomy of the oral cavity; drawing shows the lip, hard palate, soft palate, retromolar trigone, front two-thirds of the tongue, gingiva, buccal mucosa, and floor of mouth. Also shown are the teeth, uvula, and tonsil.
Figure: Oral Cavity Anatomy
Click to enlarge.

Most lip and oral cavity cancers start in squamous cells, the thin, flat cells that line the lips and oral cavity. These are called squamous cell carcinomas. Cancer cells may spread into deeper tissue as the cancer grows. Squamous cell carcinoma usually develops in areas of leukoplakia (white patches of cells that do not rub off).

Lip and oral cavity cancer is a type of head and neck cancer.

Additional Information

More Information

Here are some resources for learning more about oral cancer.

References

All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within:

Howlader N, Noone AM, Krapcho M, Miller D, Bishop K, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2013, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2013/, based on November 2015 SEER data submission, posted to the SEER web site, April 2016.

Suggested Citation

All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.

SEER Cancer Statistics Factsheets: Oral Cavity and Pharynx Cancer. National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/statfacts/html/oralcav.html

This factsheet focuses on population statistics that are based on the US population. Because these statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. To see tailored statistics, browse the SEER Cancer Statistics Review. To see statistics for a specific state, go to the State Cancer Profiles.

The statistics presented in this factsheet are based on the most recent data available, most of which can be found in the SEER Cancer Statistics Review. In some cases, different year spans may be used. Estimates for the current year are based on past data.

Cancer is a complex topic. There is a wide range of information available. This factsheet does not address causes, symptoms, diagnosis, treatment, follow-up care, or decision making, although it provides links to information in many of these areas.