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Please refer to your standard setter(s) for specific reporting requirements before using the Casefinding List

Comprehensive ICD-10 Casefinding "Must Collect" Code List for Reportable Tumors (Effective Date: 1/1/2012)

ICD-10 Code^ Explanation of Code
B21._ Human Immunodeficiency virus [HIV] disease with malignant neoplasms
C00._ – C97._ Malignant neoplasms
Note: Pilocytic/juvenile astrocytoma M-9421 moved from behavior /3 (malignant) to /1 (borderline malignancy) in ICD-O-3.  However, SEER registries will CONTINUE to report these cases and code behavior as /3 (malignant). 
D00._ - D09._ In-situ neoplasms
Note: Carcinoma in situ of the cervix (CIN III-8077/2) and Prostatic Intraepithelial Carcinoma (PIN III-8148/2) are not reportable.
D18.0 Hemangioma, any site
Note: Includes Hemangiomas of Brain, Other parts of nervous system and endocrine glands, which are reportable.
D18.1 Lymphangioma, any site
Note: Includes Lymphangiomas of Brain, Other parts of nervous system and endocrine glands, which are reportable.
D32._ Benign neoplasm of meninges (cerebral, spinal and unspecified)
D33._ Benign neoplasm of brain and other parts of central nervous system
D35.2 Benign neoplasm of pituitary gland
D35.3 Benign neoplasm of craniopharyngeal duct
D35.4 Benign neoplasm of pineal gland
D42._ Neoplasm of uncertain or unknown behavior of meninges
D43._ Neoplasm of uncertain or unknown behavior of brain and central nervous system
D44.3 – D44.5 Neoplasm of uncertain or unknown behavior of pituitary gland, craniopharyngeal duct and pineal gland
D45 Polycythemia vera (9950/3)
D46._ Myelodysplastic syndromes (9980, 9982, 9983, 9985, 9986, 9989, 9991, 9992)
D47.1 Chronic myeloproliferative disease (9960/3, 9961/3, 9963/3)
D47.3 Esssential (hemorrhagic) thrombocythemia (9962/3)
D47.7 Other specified neoplasms of uncertain/unknown behavior of lymphoid, hematopoietic (9965/3, 9966/3, 9967/3, 9971/3, 9975/3, 9987/3)
D47.9 Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified (9960/3, 9961/3, 9970/1, 9931/3)
D48.9 Neoplasm of uncertain or unknown behavior, unspecified
Note: Review code for uncertain behavior brain, CNS tumors and reportable benign endocrine glands
D76._ Certain diseases involving lymphoreticular tissue and reticulohistiocytic system

NOTE: Cases with these codes should be screened as registry time allows. These are neoplasm-related secondary conditions for which there should also be a primary diagnosis of a reportable neoplasm. Experience in the SEER registries has shown that using the supplementary list increases casefinding for benign brain and CNS, hematopoietic, and other reportable neoplasms.

(This list is to be used to help identify cases that MAY be reportable to the cancer registry. This is not a list of Reportable Neoplasms or reportable terms)

Supplementary List: ICD-10 Code List to Screen for Cancer Cases Not Identified by Other Codes (Effective Date: 1/1/2012)

ICD-10 Code^ Explanation of Code
B20._, B22 - B24 Human immunodeficiency virus [HIV] disease with other diseases
Note: Excludes HIV with malignancy (B21), see reportable list
B99 Other infectious diseases (Human papillomavirus, Retrovirus-HTLV types I, II, 2
D10._ - D31._, D34, D35.0,
D35.1, D35.5 - D35.9, D36._
Benign neoplasms (see “must collect” list for reportable benign neoplasms)
Note: Screen for incorrectly coded malignancies or reportable by agreement tumors
Note: Borderline cystadenomas M-8442, 8451, 8462, 8472, 8473, of the ovaries moved from behavior /3 (malignant) to /1 (borderline malignancy) in ICD-O-3.  SEER registries are not required to collect these cases for diagnoses made 1/1/2001 and after.  However, cases diagnosed prior to 1/1/2001 should still be abstracted and reported to SEER.
D37._ – D41._ Neoplasms of uncertain or unknown behavior (see “must collect” list for Reportable Neoplasms of uncertain or unknown behavior)
Note: Screen for incorrectly coded malignancies or reportable by agreement tumors

D44.0 - D44.2, D44.6 - D44.9

Neoplasm of uncertain or unknown behavior of other endocrine glands (see “must collect”  list for D44.3-D44.5)
Note: Screen for incorrectly coded malignancies or reportable by agreement tumors
D47.0 Histiocytic and mast cell tumors of uncertain behavior
D47.2 Monoclonal gammopathy
Note: Screen for incorrectly coded Waldenstrom’s macroglobulinemia
D48._ Neoplasms of uncertain or unknown behavior
Note: Screen for incorrectly coded malignancies or reportable by agreement tumors
D60._ Acquired pure red cell aplasia [erythroblastopenia]
Note: Screen for anemia disorder related to neoplasm
D61.1 – D61.9 Other aplastic anemias
Note: Review for miscodes
D63.0 Anemia in neoplastic disease
D64._ Other anemias
Note: Screen for anemia disorder related to neoplasm
D69.4 –  D69.9 Other thrombocytopenia
Note: Screen for incorrectly coded thrombocythemia
D70 Agranulocytosis
Note: Screen for blood disorders due to neoplasm
D72.1 Eosinophilia
Note: This is the code for eosinophilia (9964/3). Not every case of eosinophilia is associated with a malignancy. Diagnosis must be “Hypereosonophilic syndrome” to be reportable.
D75.8 Other specified diseases of blood and blood forming organs
Note: This is the code for myelofibrosis (NOS) (9961/3). Not every case of myelofibrosis is associated with a malignancy. Review terms included in ICD-O-3 to determine if case is reportable.
D80.3 – D80.5 Selective deficiency of immunoglobulin
Note: Associated with lymphoproliferative disorders
D81.0 – D81.2 Severe combined immunodeficiency [SCID]
Note: Associated with lymphoproliferative disorders
D84.9 Immunodeficiency, unspecified
Note: Associated with lymphoproliferative disorders
D89._ Other disorders involving the immune mechanism, not elsewhere classified
Note: Review for miscodes
E13._ Other specified diabetes mellitus
Note: Includes diabetes with underlying malignancy
E31.9 Polyglandular dysfunction, unspecified
Note: This is the code for “multiple endocrine neoplasia (MEN) type IIA and IIB (rare familial cancer syndrome) “
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
Note: Screen for incorrectly coded Waldenstrom’s macroglobulinemia
E88.8 Other specified metabolic disorders
Note: Includes Tumor lysis syndrome following antineoplastic drug
G31.8 Other specified degenerative diseases of nervous system
Note: Includes myelopathy in neoplastic disease
G52.8 Disorders of other specified cranial nerves
Note: Includes myelopathy in neoplastic disease
G54.8 Other nerve root and plexus disorders
Note: Includes nerve root and plexus compressions in neoplastic disease
G62.8 Other specified polyneuropathies
Note: Includes polyneuropathy disorders in neoplastic disease
G70.8 Other specified myoneural disorders
Note: Includes Eaton-Lambert syndrome in neoplastic disease
G90.8 Other disorders of autonomic nervous system
Note: Includes myelopathy in neoplastic diseases
G91.8 Other hydrocephalus
Note: Includes  hydrocephalus in neoplastic diseases
G96.8 Other specified disorders of central nervous system
Note: Includes neuropathy in neoplastic disease
J84.8 Other specified interstitial pulmonary diseases
Note: Includes Adult pulmonary Langerhans cell histiocytosis
J90 Pleural effusion, not elsewhere classified
Note: Includes malignant pleural effusion
J93.1 Other spontaneous pneumothorax
Note: Includes secondary spontaneous pneumothorax due to neoplasm
M12.8 Other specific arthropathies, not elsewhere classified
Note: Includes arthropathy in neoplastic disease
M62.8 Other specified disorders of muscle
Note: Includes disorders of muscles (due to) neoplasm
M84.4 Pathologic fracture, not elsewhere classified
Note: Includes fracture due to neoplasm
M89.8 Other specified disorders of bone
Note: Includes osteitis deformans in neoplastic disease
O01._ Hydatidiform mole
Note: This is a benign tumor that can become malignant. If malignant, it should be reported as Choriocarcinoma (9100/3) and will have a malignancy code in the C00- C97 range
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
Note: Includes: malignant neoplasm complicating pregnancy, childbirth and the pueperium
Q85.0 Neurofibromatosis (nonmalignant) (9540/1)
Note: Neurofibromatosis by itself is not reportable, but it can lead to a reportable condition
Q90._ Down’s syndrome
Note: Screen for myeloid leukemia associated with Down’s Syndrome (9898/3)
R18 Ascites
Note: Includes malignant ascites
R52.9 Pain, unspecified
Note: Includes neoplasm related pain (acute, chronic); Cancer associated pain; Pain due to malignancy (primary/secondary); Tumor associated pain
R53 Malaise and fatigue
Note: Includes neoplasm related fatigue
R59._ Enlarged lymph nodes
Note: Screen for large B-cell lymphoma arising in HHV8-associated multicentric Castleman disease (9738/3)
R82.8 Abnormal findings on cytological and histological examination of urine
R83.6, R83.7 Abnormal findings on cytological and histological examination of cerebrospinal fluid
R84.6, R84.7 Abnormal findings on cytological and histological examination of respiratory organs and thorax
R85.6, R85.7 Abnormal findings on cytological and histological examination of digestive organs and abdominal cavity
R86.6, R86.7 Abnormal findings on cytological and histological examination of male genital organs
R87.6, R87.7 Abnormal findings on cytological and histological examination of female genital organs
R89.6, R89.7 Abnormal findings on cytological and histological examination of other organs systems and tissues
R91 Abnormal findings on diagnostic imaging of lung
R92 Abnormal findings on diagnostic imaging of breast
Y42.1 Other and unspecified hormone antagonists (poisoning)
Y42.6 Adverse reaction to antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified
Y43.1 - Y43.4 Adverse effects in therapeutic use, antineoplastic products or drugs
Y43.9 Adverse effects in therapeutic use, primarily systemic agent, unspecified
Note: Includes poisoning by primarily systemic and hematological agents
Y44.9 Other and unspecified agents affecting blood constituents
Note: Includes bloodstream infection due to central venous catheter
Y63.2 Failure in dosage, overdose of radiation given during therapy
Note: Includes adverse reaction to radiation (see also Y84.2)
Y81.2 General and plastic surgery devices associated with adverse incidents-prosthetic and other implants, materials, and accessory devices
Note: Includes complications due to breast prosthesis
Y83.0 Surgical operation with transplant of whole organ
Note: Includes complications of transplant
Y84.2 Abnormal reaction, radiological procedure and radiotherapy
Note: Includes adverse reaction to radiation
Y84.9 Other medical procedures (abnormal reaction)
Note: Includes infection due to central venous catheter (see code Y44.9 for bloodstream infection)

The following codes are associated with the paraneoplastic syndrome. Paraneoplastic syndrome by itself is not cancer. It’s a disease or symptom that is the consequence of cancer but is not due to the local presence of cancer cells. A paraneoplastic syndrome may be the first sign of cancer. These codes have been removed from the Supplemental Listand are now in their own list.

ICD-10 Code^ Explanation of Code
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
E34.0 Carcinoid syndrome
E34.1 Other hypersecretion of intestinal hormones
E34.8 Other specified endocrine disorders
E83.5 Disorders of calcium metabolism
G04.8 Other encephalitis, myelitis, and encephalomyelitis
H55 Nystagmus and other irregular eye movements
L10.8 Other pemphigus
L30.4 Erythrema intertrigo
L53.8 Other specified erythematous conditions
L83 Acanthosis nigricans
L88 Pyoderma gangrenosum
L98.2 Febrile neutrophilic dermatosis [Sweet]
M33.2 Polymyositis
M33.9 Dermatopolymyositis, unspecified

^ World Health Organization. International Statistical Classification of Diseases and Related Health problems, Tenth Revision. Geneva: World Health Organization. 2007