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| HCPCS | Generic Name | Brand Name | Strength | SEER*Rx Category | Major Drug Class | Minor Drug Class | Oral (Y/N) | FDA Approval Year | FDA Discontinuation Year | CMS Effective Date | CMS Discontinuation Date | Status |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| J9601 | Linvoseltamab-gcpt | Lynozyfic | 1mg | Immunotherapy | Monoclonal Antibody | BCMA, CD3 | No | 2025 | Mar 18, 2026 | In Use | ||
| J9341 | Thiotepa (tepylute) | Tepylute | 1mg | Chemotherapy | Alkylating Agent | Nitrogen Mustard /Ethylenimine | No | 2025 | Jul 9, 2025 | In Use | ||
| C9308 | Carboplatin (avyxa) | Kyxata | 1mg | Chemotherapy | Alkylating Agent | Platinum Compound | No | 2025 | Jan 12, 2026 | Mar 18, 2026 | In Use | |
| C9175 | Treosulfan | Grafapex | 50mg | Chemotherapy | Alkylating Agent | Alkyl Sulfonate | No | 2025 | Jul 9, 2025 | Sep 8, 2025 | In Use | |
| Q5171 | Denosumab (boncres) | Boncresa | 1mg | Ancillary Therapy | Monoclonal Antibody | RANKL | No | 2025 | Jun 17, 2026 | In Use | ||
| C9307 | Linvoseltamab-gcpt | Lynozyfic | 1mg | Immunotherapy | Monoclonal Antibody | BCMA, CD3 | No | 2025 | Jan 12, 2026 | Mar 18, 2026 | In Use | |
| N/A | SEVABERTINIB | Hyrnuo | 10mg | Chemotherapy | Tyrosine Kinase Inhibitor | HER2, EGFR | Yes | 2025 | In Use | |||
| J9184 | Gemcitabine (avyxa) | Avgemsi | 200mg | Chemotherapy | Antimetabolite | Pyrimidine Analog | No | 2025 | Jan 12, 2026 | In Use | ||
| J9183 | Gemcitabine intravesical | Inlexzo | 225mg | Chemotherapy | Antimetabolite | Pyrimidine Analog | No | 2025 | Mar 18, 2026 | In Use | ||
| Q5159 | Denosumab-dssb | Ospomyv, Xbryk | 1mg | Immunotherapy | Monoclonal Antibody | RANKL | No | 2025 | Sep 8, 2025 | In Use | ||
| J9277 | Pembrolizumab and berahyaluronidase alfa-pmph | KEYTRUDA QLEX | 1mg | Immunotherapy | Checkpoint Inhibitor | PD-1 | No | 2025 | Mar 18, 2026 | In Use | ||
| C9174 | Datopotamab Deruxtecan | Datroway | 1mg | Immunotherapy | Drug Antibody Conjugate | Topoisomerase I | No | 2025 | Jul 9, 2025 | Sep 8, 2025 | In Use | |
| Q5158 | Denosumab-bnht | Bomyntra, Conexxence | 1mg | Immunotherapy | Monoclonal Antibody | RANKL | No | 2025 | Sep 8, 2025 | In Use | ||
| Q5162 | Denosumab-nxxp | Bildyos/Bilprevda | 1mg | Immunotherapy | Monoclonal Antibody | RANKL | No | 2026 | Mar 18, 2026 | In Use | ||
| N/A | Relacorilant | Lifyorli | 25mg, 100mg | Chemotherapy | Glucocorticoid Receptor (GR) Antagonist | Yes | 2026 | In Use | ||||
| Q5169 | Pegfilgrastim-unne | Armlupeg | 0.5mg | Ancillary Therapy | Immunostimulant | Granulocyte Colony-Stimulating Factor | No | 2026 | Jun 17, 2026 | In Use | ||
| C9310 | Leucovorin calcium ( avyxa) | Vykoura | 1mg | Ancillary Therapy | Chemoprotective | Antidote | No | 2026 | Jun 17, 2026 | In Use | ||
| N/A | Zidesamtinib | Jideytro | 25mg, 100mg | Chemotherapy | Tyrosine Kinase Inhibitor | ROS1, ALK, TRK | Yes | 2026 | In Use | |||
| Q5166 | Denosumab-desu | Jubereq, Osvyrti | 1mg | Immunotherapy | Monoclonal Antibody | RANKL | No | 2026 | Jun 17, 2026 | In Use | ||
| N/A | Vepdegestrant | Veppanu | 100mg, 200mg | Hormonal Therapy | Proteolysis Targeting Chimera (PROTAC) | ER, Cereblon/CRBN | Yes | 2026 | In Use | |||
| Q5167 | Denosumab-qbde | Enoby/Xtrenbo | 1mg | Immunotherapy | Monoclonal Antibody | RANKL | No | 2026 | Jun 17, 2026 | In Use |
The use of NA indicates that the HCPCS code was Not Available. NA may mean that a) the HCPCS code has
not yet been created (new drug), b) the drug is given as an oral drug or alternative route (only in
specific instances are HCPCS assigned to these medications), or c) the HCPCS could not be found or is
truly not available.
