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HER2/neu: A protein involved in normal cell growth. It is found on some types of cancer cells, including breast and ovarian. Cancer cells removed from the body may be tested for the presence of HER2/neu to help decide the best type of treatment. HER2/neu is a type of receptor tyrosine kinase. HER2/neu positive describes cancer cells that have too much of a protein called HER2 on their surface. In normal cells, HER2 helps to control cell growth. When it is made in larger than normal amounts by cancer cells, the cells may grow more quickly and be more likely to spread to other parts of the body. Checking to see if a cancer is HER2 positive may help plan treatment, which may include drugs that kill HER2 positive cancer cells. Cancers that may be HER2 positive include breast, bladder, pancreatic, ovarian, and stomach cancers.

Alternate Names
C-erbB-2
Human EGF receptor 2
human epidermal growth factor receptor 2
Primary Site
C50_ Breast