Name

Vismodegib

Alternate Names

Erivedge
GDC-0449

Abbreviations

None

Category

Chemotherapy

Subcategory

Hedgehog signaling pathway targeting agent
cyclopamine-competitive antagonist othe the smoothened receptor (SMO)

NSC Number

747691

Primary Site

Basal cell carcinoma, skin

Histology

None

Remarks

Received FDA approval January 30, 2012 for the treatment of basal cell carcinoma (BCC). Is currently in clinical trials for advanced stomach cancer, pancreatic cancer, small-cell lung cancer, colorectal cancer, medulloblastoma and chondrosarcoma.

Coding

This drug should be coded
Glossary