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Name

Thyroglobulin

Alternate Names

Proloid
Thyractin#
Thyroprotein#

Abbreviations

None

Category

Hormones and hormonal mechanisms

Subcategory

Thyroid hormone. Probably not cancer directed--verify with attending MD.

NSC Number

None

Primary Site

None

Histology

None

Remarks

A natural hormone derived from animal sources. No longer recommended due to the superiority of synthetic agents. An iodine-containing glycoprotein of high molecular weight found in the colloid of thyroid gland follicles; it is made by the follicular cells and secreted into the follicular lumen where it is iodinated, after which its iodinated tyrosyl moieties form the iodothyronines thyroxine and triiodothyronine. Thyroglobulins are then taken up by endocytosis into the follicular cells, where the iodothyronines are liberated by proteolysis, followed by release into the extracellular fluid and then to the blood stream.

Coding

This drug should be coded
Glossary