Name

Piritrexim Isethionate

Alternate Names

BW-301U
Prirtrexim

Abbreviations

None

Category

AIDS drug

Subcategory

None

NSC Number

351521

Primary Site

None

Histology

None

Remarks

A dihydrofolate reductase inhibitor. Piritrexim is an alternative to methotrexate, and may possess activity in some patients with methotrexate resistance. Promising results have been reported in head and neck cancer, metastatic melanoma, Kaposi's sarcoma, and bladder cancer; also Rx for PCP. However, additional (larger) studies are needed to define the role of piritrexim.

Coding

This drug should NOT be coded
Glossary