Name

Xpovio

Alternate Names

selinexor

Abbreviations

None

Category

Chemotherapy

Subcategory

CRM1 Inhibitor

NSC Number

None

Primary Site

None

Histology

Multiple myeloma; DLBCL

Remarks

12/18/2020 The FDA approved selinexor (XPOVIO) in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy.

6/22/2020 The FDA granted accelerated approval to selinexor (XPOVIO) for adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), not otherwise specified, including DLBCL arising from follicular lymphoma, after at least 2 lines of systemic therapy

July 3, 2019.FDA granted accelerated approval to selinexor (XPOVIO) in combination with dexamethasone for adult patients with relapsed or refractory multiple myeloma (RRMM) who have received at least four prior therapies and whose disease is refractory to at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti-CD38 monoclonal antibody.

Coding

This drug should be coded
Glossary