This section provides number of cases and age-adjusted incidence rates by major cancer sites and subsites and by demographic factors among children aged 0 to 19 in the National Childhood Cancer Registry (NCCR).

  • Age-adjusted incidence rates are highest for leukemia (49.6 per 1,000,000), for malignant central nervous system neoplasms (32.7 per 1,000,000), and lymphomas (29.6 per 1,000,000) from 2008-2017 (Figure 3.1).
  • The most common subsite of leukemias is lymphoid leukemia (Table 3.1).
  • Statistics for non-malignant central nervous system neoplasms and germ cell tumors are available starting with 2004 data (Table 3.2).

Figure 3.1: Age-Adjusted Incidence Rates* by Major Cancer Site Groups, 2008-2017#

2008-2017 Incidence Rates per 1,000,000 by Major ICCC Site Group

# Cancer site definitions are based on International Classification of Childhood Cancer (ICCC). All cancers are malignant unless otherwise noted.
*Rates are per 1,000,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
Download data for Figure 3.1 (XLSX, 11 KB).

Table 3.1: Age-Adjusted Incidence Rates* and Number of Cases By Period of Diagnosis for Major Cancer Sites and Subsites#

  1995-2017 1995-2007 2008-2017
Rate Cases Rate Cases Rate Cases
All ICCC Sites Excluding Non-Malignant Central Nervous System and Germ Cell 177.9 218,246 168.9 115,065 189.1 103,181
I. LEUKEMIAS, MYELOPROLIFERATIVE AND MYELODYSPLASTIC DISEASES 46.9 57,495 44.8 30,558 49.6 26,937
   I.a. Lymphoid leukemias 34.2 41,791 33.0 22,488 35.6 19,303
   I.b. Acute myeloid leukemias 8.2 10,123 8.0 5,442 8.6 4,681
   I.c. Chronic myeloproliferative diseases 2.2 2,725 1.8 1,230 2.7 1,495
   I.d. Myelodysplastic syndrome and other myeloproliferative diseases 1.2 1,468 0.9 624 1.5 844
   I.e. Unspecified and other specified leukemias 1.1 1,388 1.1 774 1.1 614
II. LYMPHOMAS AND RETICULOENDOTHELIAL NEOPLASMS 26.8 32,948 24.6 16,727 29.6 16,221
   II.a. Hodgkin lymphomas 12.3 15,155 12.3 8,364 12.3 6,791
   II.b. Non-Hodgkin lymphomas (except Burkitt lymphoma) 9.2 11,218 8.4 5,697 10.1 5,521
   II.c. Burkitt lymphoma 2.5 2,988 2.4 1,644 2.5 1,344
   II.d. Miscellaneous lymphoreticular neoplasms 2.5 3,025 1.0 654 4.4 2,371
   II.e. Unspecified lymphomas 0.5 562 0.5 368 0.4 194
III. CENTRAL NERVOUS SYSTEM AND MISCELLANEOUS INTRACRANIAL AND INTRASPINAL NEOPLASMS 31.3 38,290 30.3 20,610 32.7 17,680
   III.a. Ependymomas and choroid plexus tumor 2.6 3,224 2.5 1,739 2.7 1,485
   III.b. Astrocytomas 15.9 19,476 15.2 10,309 16.9 9,167
   III.c. Intracranial and intraspinal embryonal tumors 6.2 7,568 6.3 4,311 6.0 3,257
   III.d. Other gliomas 5.5 6,659 5.1 3,480 5.9 3,179
   III.e. Other specified intracranial and intraspinal neoplasms 0.6 777 0.6 426 0.6 351
   III.f. Unspecified intracranial and intraspinal neoplasms 0.5 586 0.5 345 0.4 241
IV. NEUROBLASTOMA AND OTHER PERIPHERAL NERVOUS CELL TUMORS 8.4 10,386 8.3 5,692 8.6 4,694
   IV.a. Neuroblastoma and ganglioneuroblastoma 8.2 10,066 8.0 5,524 8.4 4,542
   IV.b. Other peripheral nervous cell tumors 0.3 320 0.2 168 0.3 152
V. RETINOBLASTOMA 3.3 4,082 3.3 2,272 3.3 1,810
VI. RENAL TUMORS 6.7 8,231 6.5 4,446 7.0 3,785
   VI.a. Nephroblastoma and other non-epithelial renal tumors 6.1 7,436 5.9 4,064 6.2 3,372
   VIb Renal carcinomas 0.6 764 0.5 364 0.7 400
   VI.c. Unspecified malignant renal tumors 0.0 31 0.0 18 0.0 13
VII. HEPATIC TUMORS 2.4 2,990 2.1 1,465 2.8 1,525
   VII.a. Hepatoblastoma and mesenchymal tumors of liver 1.8 2,245 1.6 1,069 2.2 1,176
   VII.b. Hepatic carcinomas 0.6 722 0.6 385 0.6 337
   VII.c. Unspecified malignant hepatic tumors 0.0 23 0.0 11 0.0 12
VIII. MALIGNANT BONE TUMORS 9.2 11,326 9.2 6231 9.4 5,095
   VIII.a. Osteosarcomas 5.2 6,372 5.2 3,530 5.2 2,842
   VIII.b. Chondrosarcomas 0.4 473 0.4 265 0.4 208
  VIII.c. Ewing tumor and related sarcomas of bone 3.0 3,661 2.9 2,002 3.1 1,659
   VIII.d. Other specified malignant bone tumors 0.5 592 0.5 318 0.5 274
   VIII.e. Unspecified malignant bone tumors 0.2 228 0.2 116 0.2 112
IX. SOFT TISSUE AND OTHER EXTRAOSSEOUS SARCOMAS 12.0 14,773 11.8 8,038 12.4 6,735
   IX.a. Rhabdomyosarcomas 4.7 5,714 4.7 3,177 4.7 2,537
   IX.b. Fibrosarcomas, peripheral nerve sheath tumors and oth fibrous neoplasms 1.3 1,605 1.3 913 1.3 692
   IX.c. Kaposi sarcoma 0.1 71 0.1 42 0.1 29
   IX.d. Other specified soft tissue sarcomas 4.6 5,701 4.5 3,055 4.8 2,646
   IX.e. Unspecified soft tissue sarcomas 1.4 1,682 1.3 851 1.5 831
X. GERM CELL TUMORS, TROPHOBLASTIC TUMORS AND NEOPLASMS OF GONADS 11.4 14,091 11.0 7,496 11.9 6,595
   X.a. Intracranial and intraspinal germ cell tumors 1.7 2,120 1.6 1,085 1.9 1,035
   X.b. Malignant extracranial and extragonadal germ cell tumors 1.5 1,851 1.6 1,067 1.4 784
   X.c. Malignant gonadal germ cell tumors 7.4 9,171 7.1 4,856 7.8 4,315
   X.d. Gonadal carcinomas 0.4 542 0.4 282 0.5 260
   X.e. Other and unspecified malignant gonadal tumors 0.3 407 0.3 206 0.4 201
XI. OTHER MALIGNANT EPITHELIAL NEOPLASMS AND MALIGNANT MELANOMAS 18.3 22,546 16.1 10,926 21.0 11,620
   XI.a. Adrenocortical carcinomas 0.2 262 0.2 147 0.2 115
   XI.b. Thyroid carcinomas 7.9 9,733 6.1 4,141 10.1 5,592
   XI.c. Nasopharyngeal carcinomas 0.5 669 0.5 374 0.5 295
   XI.d. Malignant melanomas 4.7 5,750 5.2 3,526 4.0 2,224
   XI.e. Skin carcinomas 0.1 125 0.1 67 0.1 58
   XI.f. Other and unspecified carcinomas 4.9 6,007 3.9 2,671 6.0 3,336
XII. OTHER AND UNSPECIFIED MALIGNANT NEOPLASMS 0.9 1,088 0.9 604 0.9 484
   XII.a. Other specified malignant tumors 0.4 530 0.4 252 0.5 278
   XII.b. Other unspecified malignant tumors 0.5 558 0.5 352 0.4 206

* Rates are per 1,000,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
# Excludes Non-Malignant Central Nervous System and Germ Cell tumors. Cancer site definitions are based on International Classification of Childhood Cancer (ICCC).

Table 3.2: Age-Adjusted Incidence Rates* and Number of Cases By Period of Diagnosis for Non-Malignant Central Nervous System and Germ Cell Cancers#

  2004-2007 2008-2017
Rate Cases Rate Cases
Total 15.9 3,490 20.3 11,123
III. CENTRAL NERVOUS SYSTEM AND MISCELLANEOUS INTRACRANIAL AND INTRASPINAL NEOPLASMS 15.5 3,386 19.8 10,825
   III.a. Ependymomas and choroid plexus tumor 1.2 268 1.3 698
   III.b. Astrocytomas 0.8 162 0.8 421
   III.c. Intracranial and intraspinal embryonal tumors 0 0 0 2
   III.d. Other gliomas 0.1 28 0.4 191
   III.e. Other specified intracranial and intraspinal neoplasms 12 2,635 15.6 8,556
   III.f. Unspecified intracranial and intraspinal neoplasms 1.3 293 1.8 957
X. GERM CELL TUMORS, TROPHOBLASTIC TUMORS AND NEOPLASMS OF GONADS 0.5 104 0.5 298
   X.a. Intracranial and intraspinal germ cell tumors 0.5 104 0.5 298

* Rates are per 1,000,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
# Cancer site definitions are based on International Classification of Childhood Cancer (ICCC).

Table 3.3: Recent Incidence Rates* and Number of Cases By Age at Diagnosis, 2008-2017#

  <1 year 1-4 years 5-9 years 10-14 years 15-19 years
Rate Cases Rate Cases Rate Cases Rate Cases Rate Cases
Total Excluding Non-Malignant Central Nervous System and Germ Cell 273.2 7,147 231.5 24,436 133.7 17,858 150.0 20,398 235.7 33,342
Total Including Non-Malignant Central Nervous System and Germ Cell 289.2 7,567 241.5 25,489 146.9 19,623 170.3 23,159 272.0 38,466
I. LEUKEMIAS, MYELOPROLIFERATIVE AND MYELODYSPLASTIC DISEASES 54.0 1414 93.8 9,898 43.7 5,840 34.7 4,716 35.8 5,069
   I.a. Lymphoid leukemias 18.9 495 78.6 8,292 36.0 4,810 23.1 3,147 18.1 2,559
   I.b. Acute myeloid leukemias 19.6 513 10.8 1,140 4.7 625 7.3 989 10.0 1,414
   I.c. Chronic myeloproliferative diseases 5.6 147 1.3 142 1.2 157 2.3 307 5.2 742
   I.d. Myelodysplastic syndrome and other myeloproliferative diseases 7.3 192 1.6 173 0.9 114 1.1 156 1.5 209
   I.e. Unspecified and other specified leukemias 2.6 67 1.4 151 1.0 134 0.9 117 1.0 145
II. LYMPHOMAS AND RETICULOENDOTHELIAL NEOPLASMS 19.7 515 16.5 1,741 19.2 2,563 29.1 3,953 52.7 7,449
   II.a. Hodgkin lymphomas 0.1 2 1.0 101 4.0 528 12.3 1,674 31.7 4,486
   II.b. Non-Hodgkin lymphomas (except Burkitt lymphoma) 2.6 69 5.9 624 7.8 1,048 10.6 1,446 16.5 2,334
   II.c. Burkitt lymphoma 0.1 3 2.2 230 3.1 416 2.8 383 2.2 312
   II.d. Miscellaneous lymphoreticular neoplasms 16.7 438 7.3 774 4.1 541 3.0 408 1.5 210
   II.e. Unspecified lymphomas 0.1 3 0.1 12 0.2 30 0.3 42 0.8 107
III. Malignant CENTRAL NERVOUS SYSTEM AND MISCELLANEOUS INTRACRANIAL AND INTRASPINAL NEOPLASMS 35.7 935 45.7 4,819 36.2 4,839 28.3 3,848 22.9 3,239
   III.a. Malignant Ependymomas and choroid plexus tumor 5.0 132 5.4 568 2.2 297 1.8 246 1.7 242
   III.b. Malignant Astrocytomas 13.6 355 22.4 2,368 18.4 2,456 15.8 2,146 13.0 1,842
   III.c. Malignant Intracranial and intraspinal embryonal tumors 12.0 313 10.5 1,113 7.1 948 4.0 548 2.4 335
   III.d. Malignant Other gliomas 3.1 80 6.1 644 7.6 1,012 5.7 780 4.7 663
   III.e. Malignant Other specified intracranial and intraspinal neoplasms 0.9 23 0.8 81 0.6 78 0.5 74 0.7 95
   III.f. Malignant Unspecified intracranial and intraspinal neoplasms 1.2 32 0.4 45 0.4 48 0.4 54 0.4 62
III. Non-Malignant CENTRAL NERVOUS SYSTEM AND MISCELLANEOUS INTRACRANIAL AND INTRASPINAL NEOPLASMS 14.1 370 9.2 974 12.8 1,704 19.9 2,701 35.9 5,076
   III.a. Non-Malignant Ependymomas and choroid plexus tumor 5.1 134 1.4 146 0.7 93 1.1 147 1.3 178
   III.b. Non-Malignant Astrocytomas 1.6 43 1.0 101 0.8 106 0.7 96 0.5 75
   III.c. Non-Malignant Intracranial and intraspinal embryonal tumors 0.0 0 0.0 0 0.0 2 0.0 0 0.0 0
   III.d. Non-Malignant Other gliomas 0.1 2 0.3 35 0.4 56 0.5 63 0.2 35
   III.e. Non-Malignant Other specified intracranial and intraspinal neoplasms 5.1 133 5.5 584 9.6 1,280 15.5 2,109 31.5 4,450
   III.f. Non-Malignant Unspecified intracranial and intraspinal neoplasms 2.2 58 1.0 108 1.3 167 2.1 286 2.4 338
IV. NEUROBLASTOMA AND OTHER PERIPHERAL NERVOUS CELL TUMORS 58.3 1,524 21.5 2,268 4.4 585 1.3 182 1.0 135
   IV.a. Neuroblastoma and ganglioneuroblastoma 58.1 1,520 21.3 2248 4.2 560 1.0 140 0.5 74
   IV.b. Other peripheral nervous cell tumors 0.2 4 0.2 20 0.2 25 0.3 42 0.4 61
V. RETINOBLASTOMA 30.6 800 8.8 933 0.5 62 0.1 12 0.0 3
VI. RENAL TUMORS 16.1 421 19.6 2,072 6.1 811 1.5 198 2.0 283
   VI.a. Nephroblastoma and other non-epithelial renal tumors 15.8 414 19.5 2,055 5.7 755 0.7 101 0.3 47
   VI.b. Renal carcinomas 0.2 5 0.1 7 0.4 56 0.7 97 1.7 235
   VI.c. Unspecified malignant renal tumors 0.1 2 0.1 10 0.0 0 0.0 0 0.0 1
VII. HEPATIC TUMORS 13.9 363 6.2 658 1.1 144 1.2 164 1.4 196
   VII.a. Hepatoblastoma and mesenchymal tumors of liver 13.5 354 6.0 634 0.8 107 0.5 64 0.1 17
   VII.b. Hepatic carcinomas 0.2 6 0.2 24 0.3 34 0.7 98 1.2 175
   VII.c. Unspecified malignant hepatic tumors 0.1 3 0.0 0 0.0 3 0.0 2 0.0 4
VIII. MALIGNANT BONE TUMORS 0.7 19 1.9 198 6.1 813 14.7 1,998 14.6 2,067
   VIII.a. Osteosarcomas 0.0 1 0.4 44 3.2 433 8.8 1,200 8.2 1,164
   VIII.b. Chondrosarcomas 0.0 0 0.0 5 0.1 13 0.5 65 0.9 125
  VIII.c. Ewing tumor and related sarcomas of bone 0.5 12 1.1 114 2.4 317 4.5 611 4.3 605
   VIII.d. Other specified malignant bone tumors 0.1 2 0.2 26 0.3 35 0.7 94 0.8 117
   VIII.e. Unspecified malignant bone tumors 0.2 4 0.1 9 0.1 15 0.2 28 0.4 56
IX. SOFT TISSUE AND OTHER EXTRAOSSEOUS SARCOMAS 17.9 468 11.2 1,182 8.7 1,163 11.9 1,620 16.3 2,302
   IX.a. Rhabdomyosarcomas 5.8 151 7.8 824 4.3 570 3.5 478 3.6 514
   IX.b. Fibrosarcomas, peripheral nerve sheath tumors and oth fibrous neoplasms 4.9 127 0.5 57 0.6 85 1.1 153 1.9 270
   IX.c. Kaposi sarcoma 0.1 3 0.0 2 0.0 1 0.0 2 0.1 21
   IX.d. Other specified soft tissue sarcomas 4.7 122 2.1 226 2.8 376 5.5 744 8.3 1,178
   IX.e.Unspecified soft tissue sarcomas 2.5 65 0.7 73 1.0 131 1.8 243 2.3 319
X. Malignant GERM CELL TUMORS, TROPHOBLASTIC TUMORS AND NEOPLASMS OF GONADS 20.0 524 3.3 352 2.8 374 8.0 1,083 30.1 4,262
   X.a. Malignant Intracranial and intraspinal germ cell tumors 2.2 58 0.3 33 1.4 182 2.9 390 2.6 372
   X.b. Malignant Malignant extracranial and extragonadal germ cell tumors 12.7 333 1.3 142 0.1 17 0.4 48 1.7 244
   X.c. Malignant Malignant gonadal germ cell tumors 4.7 124 1.6 171 1.1 151 4.2 573 23.3 3,296
   X.d. Malignant Gonadal carcinomas 0.0 1 0.0 2 0.0 5 0.2 29 1.6 223
   X.e. Malignant Other and unspecified malignant gonadal tumors 0.3 8 0.0 4 0.1 19 0.3 43 0.9 127
X. Non-Malignant GERM CELL TUMORS, TROPHOBLASTIC TUMORS AND NEOPLASMS OF GONADS 1.9 50 0.7 79 0.5 61 0.4 60 0.3 48
   X.a. Non-Malignant Intracranial and intraspinal germ cell tumors 1.9 50 0.7 79 0.5 61 0.4 60 0.3 48
   X.b. Non-Malignant extracranial and extragonadal germ cell tumors 0.0 0 0.0 0 0.0 0 0.0 0 0.0 0
   X.c. Non-Malignant gonadal germ cell tumors 0.0 0 0.0 0 0.0 0 0.0 0 0.0 0
   X.d. Non-Malignant Gonadal carcinomas 0.0 0 0.0 0 0.0 0 0.0 0 0.0 0
   X.e. Non-Malignant Other and unspecified gonadal tumors 0.0 0 0.0 0 0.0 0 0.0 0 0.0 0
XI. OTHER MALIGNANT EPITHELIAL NEOPLASMS AND MALIGNANT MELANOMAS 3.8 99 1.8 187 4.7 624 18.7 2,549 57.7 8,161
   XI.a. Adrenocortical carcinomas 0.3 9 0.3 35 0.1 8 0.2 23 0.3 40
   XI.b. Thyroid carcinomas 0.3 9 0.2 25 1.4 187 8.5 1,155 29.8 4,216
   XI.c. Nasopharyngeal carcinomas 0.0 0 0.0 0 0.1 11 0.8 102 1.3 182
   XI.d. Malignant melanomas 1.8 46 1.0 107 1.7 223 2.9 397 10.3 1,451
   XI.e. Skin carcinomas 0.0 1 0.0 0 0.0 5 0.1 16 0.3 36
   XI.f. Other and unspecified carcinomas 1.3 34 0.2 20 1.4 190 6.3 856 15.8 2,236
XII. OTHER AND UNSPECIFIED MALIGNANT NEOPLASMS 2.5 65 1.2 128 0.3 40 0.6 75 1.2 176
   XII.a. Other specified malignant tumors 1.4 37 1.0 102 0.1 17 0.3 40 0.6 82
   XII.b. Other unspecified malignant tumors 1.1 28 0.2 26 0.2 23 0.3 35 0.7 94

* Rates are per 1,000,000
# Cancer site definitions are based on International Classification of Childhood Cancer (ICCC). All cancers are malignant unless otherwise noted.

Table 3.4: Age-Adjusted Incidence Rates* and Number of Cases By Race/Ethnicity, 2008-2017#

  Non-Hispanic White Non-Hispanic Black Non-Hispanic American Indian/ Alaska Native Non-Hispanic Asian/ Pacific Islander Hispanic (All Races)
Rate Cases Rate Cases Rate Cases Rate Cases Rate Cases
All ICCC Sites Excluding Non-Malignant Central Nervous System and Germ Cell 201.8 55,520 144.6 11,382 144.5 423 165.7 5,778 185.2 28,500
All ICCC Sites Including Non-Malignant Central Nervous System and Germ Cell 223.3 61,534 162.0 12,763 163.3 480 180.3 6,284 204.6 31,417
I. LEUKEMIAS, MYELOPROLIFERATIVE AND MYELODYSPLASTIC DISEASES 47.7 12,886 31.7 2,483 45 130 48.8 1,703 60.3 9,396
   I.a. Lymphoid leukemias 34.8 9,330 18.3 1,427 31.8 91 32.7 1,143 45.3 7,083
   I.b. Acute myeloid leukemias 8.0 2,188 8.0 634 8.8 26 10.7 373 9.1 1,403
   I.c. Chronic myeloproliferative diseases 2.6 728 3 238 1.6 5 2.7 94 2.6 401
   I.d. Myelodysplastic syndrome and other myeloproliferative diseases 1.5 395 1.4 109 1.7 5 1.8 64 1.7 258
   I.e. Unspecified and other specified leukemias 0.9 245 1 75 1 3 0.8 29 1.6 251
II. LYMPHOMAS AND RETICULOENDOTHELIAL NEOPLASMS 31.9 8,957 24.9 1,976 19 56 26.4 917 26.9 4,082
   II.a. Hodgkin lymphomas 14 4,014 10.7 856 6.5 20 8.5 294 10.4 1,539
   II.b. Non-Hodgkin lymphomas (except Burkitt lymphoma) 10.0 2,805 10.7 842 6.1 18 11.1 385 9.1 1,379
   II.c. Burkitt lymphoma 3.1 841 1.6 124 2.1 6 2.3 81 1.8 269
   II.d. Miscellaneous lymphoreticular neoplasms 4.5 1,212 1.7 128 3.9 11 4.2 147 5.2 827
   II.e. Unspecified lymphomas 0.3 85 0.3 26 0.4 1 0.3 10 0.5 68
III. Malignant CENTRAL NERVOUS SYSTEM AND MISCELLANEOUS INTRACRANIAL AND INTRASPINAL NEOPLASMS 38.3 10,386 27.3 2,127 24.9 72 23.7 824 25.6 3,975
   III.a. Malignant Ependymomas and choroid plexus tumor 2.9 795 2.3 181 1.4 4 2.2 78 2.6 409
   III.b. Malignant Astrocytomas 21 5,638 13.2 1,027 14.1 41 11.2 388 12.3 1,901
   III.c. Malignant Intracranial and intraspinal embryonal tumors 6.7 1,789 4.5 352 5.6 16 5.7 199 5.4 854
   III.d. Malignant Other gliomas 6.9 1,885 5.7 443 3.8 11 3.9 136 4.2 655
   III.e. Malignant Other specified intracranial and intraspinal neoplasms 0.6 153 1.1 85 0 0 0.4 13 0.6 93
   III.f. Malignant Unspecified intracranial and intraspinal neoplasms 0.5 126 0.5 39 0.0 0 0.3 10 0.4 63
III. Non-Malignant CENTRAL NERVOUS SYSTEM AND MISCELLANEOUS INTRACRANIAL AND INTRASPINAL NEOPLASMS 20.9 5,843 16.9 1,344 18.8 57 14.2 493 19 2,851
   III.a. Non-Malignant Ependymomas and choroid plexus tumor 1.6 425 0.8 60 1 3 0.9 30 1.1 165
   III.b. Non-Malignant Astrocytomas 1 206 0.8 62 0.0 0 0.9 30 0.7 112
   III.c. Non-Malignant Intracranial and intraspinal embryonal tumors 0.0 2 0.0 0 0.0 0 0.0 0 0.0 0
   III.d. Non-Malignant Other gliomas 0.4 110 0.4 28 0.3 1 0.2 8 0.3 39
   III.e. Non-Malignant Other specified intracranial and intraspinal neoplasms 16.2 4,565 13.6 1,083 15.8 48 11.5 399 15.3 2,281
   III.f. Non-Malignant Unspecified intracranial and intraspinal neoplasms 1.9 535 1.4 111 1.6 5 0.8 26 1.7 254
IV. NEUROBLASTOMA AND OTHER PERIPHERAL NERVOUS CELL TUMORS 10.5 2,780 7.6 593 4.9 14 7.7 271 5.9 954
   IV.a. Neuroblastoma and ganglioneuroblastoma 10.2 2,698 7.3 567 4.6 13 7.5 266 5.6 918
   IV.b. Other peripheral nervous cell tumors 0.3 82 0.3 26 0.3 1 0.1 5 0.2 36
V. RETINOBLASTOMA 3 794 3.6 279 3.2 9 3.6 127 3.5 577
VI. RENAL TUMORS 7.4 1,960 9 701 4.3 12 4.1 144 5.7 911
   VI.a. Nephroblastoma and other non-epithelial renal tumors 6.7 1,769 7.8 602 3.2 9 3.4 119 5.1 824
   VI.b. Renal carcinomas 0.7 187 1.2 98 1.1 3 0.7 23 0.6 82
   VI.c. Unspecified malignant renal tumors 0 4 0 1 0 0 0.1 2 0 5
VII. HEPATIC TUMORS 2.6 700 2.2 174 3.1 9 3.2 114 3.1 502
   VII.a. Hepatoblastoma and mesenchymal tumors of liver 2 524 1.6 125 2.5 7 2.7 94 2.5 407
   VII.b. Hepatic carcinomas 0.6 169 0.6 46 0.6 2 0.6 20 0.6 93
   VII.c. Unspecified malignant hepatic tumors 0 7 0.0 3 0.0 0 0.0 0 0.0 2
VIII. MALIGNANT BONE TUMORS 10.0 2,784 7.3 574 6.1 18 8.2 283 9.3 1,382
   VIII.a. Osteosarcomas 4.9 1,386 5.7 448 3.4 10 4.4 153 5.5 818
   VIII.b. Chondrosarcomas 0.5 128 0.3 24 0 0 0.3 10 0.3 44
  VIII.c. Ewing tumor and related sarcomas of bone 3.9 1,097 0.7 55 2.1 6 2.6 90 2.6 392
   VIII.d. Other specified malignant bone tumors 0.5 133 0.3 23 0.6 2 0.6 22 0.6 90
   VIII.e. Unspecified malignant bone tumors 0.1 40 0.3 24 0 0 0.2 8 0.3 38
IX. SOFT TISSUE AND OTHER EXTRAOSSEOUS SARCOMAS 12.7 3487 13.2 1,039 8.5 25 9.4 327 11.4 1,745
   IX.a. Rhabdomyosarcomas 4.8 1,307 5.2 410 3.5 10 3.6 127 4.2 650
   IX.b. Fibrosarcomas, peripheral nerve sheath tumors and oth fibrous neoplasms 1.4 374 1.2 98 1 3 0.9 32 1.1 166
   IX.c. Kaposi sarcoma 0.0 5 0.2 15 0.0 0 0.0 1 0.1 8
   IX.d. Other specified soft tissue sarcomas 4.8 1,350 4.8 380 3.4 10 3.7 130 4.8 728
   IX.e. Unspecified soft tissue sarcomas 1.6 451 1.7 136 0.7 2 1.1 37 1.3 193
X. Malignant GERM CELL TUMORS, TROPHOBLASTIC TUMORS AND NEOPLASMS OF GONADS 11.3 3,224 6.3 504 8.7 27 12.4 431 15.5 2,310
   X.a. Malignant Intracranial and intraspinal germ cell tumors 1.9 533 1.2 93 0.4 1 3.6 123 1.8 276
   X.b. Malignant Malignant extracranial and extragonadal germ cell tumors 1.3 345 1.3 102 2 6 2.1 72 1.5 234
   X.c. Malignant Malignant gonadal germ cell tumors 7.3 2,119 3.1 245 6.4 20 6 210 11.2 1,664
   X.d. Malignant Gonadal carcinomas 0.5 141 0.2 20 0 0 0.6 20 0.5 76
   X.e. Malignant Other and unspecified malignant gonadal tumors 0.3 86 0.5 44 0 0 0.2 6 0.4 60
X. Non-Malignant GERM CELL TUMORS, TROPHOBLASTIC TUMORS AND NEOPLASMS OF GONADS 0.6 171 0.5 37 0 0 0.4 13 0.4 66
   X.a. Non-Malignant Intracranial and intraspinal germ cell tumors 0.6 171 0.5 37 0 0 0.4 13 0.4 66
   X.b. Non-Malignant extracranial and extragonadal germ cell tumors 0 0 0 0 0 0 0 0 0 0
   X.c. Non-Malignant gonadal germ cell tumors 0 0 0 0 0 0 0 0 0 0
   X.d. Non-Malignant Gonadal carcinomas 0 0 0 0 0 0 0 0 0 0
   X.e. Non-Malignant Other and unspecified gonadal tumors 0 0 0 0 0 0 0 0 0 0
XI. OTHER MALIGNANT EPITHELIAL NEOPLASMS AND MALIGNANT MELANOMAS 25.5 7,319 10.6 857 15 46 17.6 613 17.2 2,535
   XI.a. Adrenocortical carcinomas 0.2 67 0.1 8 0.4 1 0.2 7 0.2 31
   XI.b. Thyroid carcinomas 11.9 3,429 3.7 298 6.5 20 10.9 378 9.4 1,388
   XI.c. Nasopharyngeal carcinomas 0.3 84 1.4 113 0.7 2 0.8 27 0.5 67
   XI.d. Malignant melanomas 6.4 1,816 0.5 43 0.7 2 1.1 40 1.4 215
   XI.e. Skin carcinomas 0.1 34 0.1 6 0 0 0.1 2 0.1 12
   XI.f. Other and unspecified carcinomas 6.6 1,889 4.8 389 6.8 21 4.6 159 5.6 822
XII. OTHER AND UNSPECIFIED MALIGNANT NEOPLASMS 0.9 243 0.9 75 1.8 5 0.7 24 0.8 131
   XII.a. Other specified malignant tumors 0.5 145 0.5 39 1.4 4 0.5 17 0.4 69
   XII.b. Other unspecified malignant tumors 0.4 98 0.5 36 0.4 1 0.2 7 0.4 62

* Rates are per 1,000,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
# Cancer site definitions are based on International Classification of Childhood Cancer (ICCC). All cancers are malignant unless otherwise noted.