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Table 30.1
Myelodysplastic Syndromes, Chronic Myeloproliferative Disorders, and Chronic Myelomonocytic Leukemia
Counts, Percents and Age-Adjusted Incidence Ratesa by Subtype
18 SEER Geographic Areas 2009-2013
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Total | 34,645 | 100.0% | 7.9 | 18,985 | 100.0% | 10.2 | 15,660 | 100.0% | 6.3 |
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Myelodysplastic Syndromes (MDS) | 21,338 | 100.0% | 4.9 | 12,098 | 100.0% | 6.7 | 9,240 | 100.0% | 3.7 |
| Refractory anemia (RA), NOS | 1,707 | 8.0% | 0.4 | 890 | 7.4% | 0.5 | 817 | 8.8% | 0.3 |
| RA with ringed sideroblasts | 1,374 | 6.4% | 0.3 | 769 | 6.4% | 0.4 | 605 | 6.5% | 0.2 |
| RA with excess blasts (RAEB) | 3,057 | 14.3% | 0.7 | 1,844 | 15.2% | 1.0 | 1,213 | 13.1% | 0.5 |
| RAEB in transformation | 24 | 0.1% | 0.0 | - | - | - | - | - | - |
| Refractory cytopenia w/multilineage dysplasia | 1,568 | 7.3% | 0.4 | 1,036 | 8.6% | 0.6 | 532 | 5.8% | 0.2 |
| Myelodysplastic syndrome with 5q deletion | 689 | 3.2% | 0.2 | 286 | 2.4% | 0.2 | 403 | 4.4% | 0.2 |
| Therapy-related myelodysplastic syndrome | 85 | 0.4% | 0.0 | 42 | 0.3% | 0.0 | 43 | 0.5% | 0.0 |
| Myelodysplastic syndrome, NOS | 12,834 | 60.1% | 3.0 | 7,218 | 59.7% | 4.0 | 5,616 | 60.8% | 2.2 |
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Chronic Myeloproliferative Disorders (CMD) | 11,409 | 100.0% | 2.5 | 5,676 | 100.0% | 2.8 | 5,733 | 100.0% | 2.4 |
| Polycythemia vera | 4,701 | 41.2% | 1.0 | 2,659 | 46.8% | 1.3 | 2,042 | 35.6% | 0.8 |
| Chronic myeloproliferative disease, NOS | 288 | 2.5% | 0.1 | 141 | 2.5% | 0.1 | 147 | 2.6% | 0.1 |
| Myelosclerosis with myeloid metaplasia | 1,520 | 13.3% | 0.3 | 910 | 16.0% | 0.5 | 610 | 10.6% | 0.2 |
| Essential thrombocythemia | 4,747 | 41.6% | 1.1 | 1,869 | 32.9% | 0.9 | 2,878 | 50.2% | 1.2 |
| Chronic neutrophilic leukemia | 31 | 0.3% | 0.0 | 21 | 0.4% | 0.0 | - | - | - |
| Hypereosinophilic syndrome | 122 | 1.1% | 0.0 | 76 | 1.3% | 0.0 | 46 | 0.8% | 0.0 |
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Chronic Myelomonocytic Leukemia (CMML) | 1,898 | 100.0% | 0.4 | 1,211 | 100.0% | 0.7 | 687 | 100.0% | 0.3 |
Footnotes:
Source: SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey and Georgia excluding ATL/RG).
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
- Statistic not shown due to fewer than 16 cases during the time period.
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