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Table 30.1
Myelodysplastic Syndromes, Chronic Myeloproliferative Disorders, and Chronic Myelomonocytic Leukemia
Counts, Percents and Age-Adjusted Incidence Ratesa by Subtype
18 SEER Geographic Areas 2008-2012
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Total | 34,431 | 100.0% | 8.0 | 18,802 | 100.0% | 10.3 | 15,629 | 100.0% | 6.4 |
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Myelodysplastic Syndromes (MDS) | 21,056 | 100.0% | 5.0 | 11,879 | 100.0% | 6.8 | 9,177 | 100.0% | 3.7 |
| Refractory anemia (RA), NOS | 1,856 | 8.8% | 0.4 | 968 | 8.1% | 0.6 | 888 | 9.7% | 0.4 |
| RA with ringed sideroblasts | 1,378 | 6.5% | 0.3 | 782 | 6.6% | 0.4 | 596 | 6.5% | 0.2 |
| RA with excess blasts (RAEB) | 2,871 | 13.6% | 0.7 | 1,717 | 14.5% | 0.9 | 1,154 | 12.6% | 0.5 |
| RAEB in transformation | 54 | 0.3% | 0.0 | 34 | 0.3% | 0.0 | 20 | 0.2% | 0.0 |
| Refractory cytopenia w/multilineage dysplasia | 1,482 | 7.0% | 0.4 | 975 | 8.2% | 0.5 | 507 | 5.5% | 0.2 |
| Myelodysplastic syndrome with 5q deletion | 634 | 3.0% | 0.1 | 261 | 2.2% | 0.1 | 373 | 4.1% | 0.2 |
| Therapy-related myelodysplastic syndrome | 291 | 1.4% | 0.1 | 156 | 1.3% | 0.1 | 135 | 1.5% | 0.1 |
| Myelodysplastic syndrome, NOS | 12,490 | 59.3% | 2.9 | 6,986 | 58.8% | 4.0 | 5,504 | 60.0% | 2.2 |
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Chronic Myeloproliferative Disorders (CMD) | 11,581 | 100.0% | 2.6 | 5,783 | 100.0% | 2.9 | 5,798 | 100.0% | 2.4 |
| Polycythemia vera | 4,406 | 38.0% | 1.0 | 2,461 | 42.6% | 1.2 | 1,945 | 33.5% | 0.8 |
| Chronic myeloproliferative disease, NOS | 1,011 | 8.7% | 0.2 | 547 | 9.5% | 0.3 | 464 | 8.0% | 0.2 |
| Myelosclerosis with myeloid metaplasia | 1,447 | 12.5% | 0.3 | 878 | 15.2% | 0.5 | 569 | 9.8% | 0.2 |
| Essential thrombocythemia | 4,539 | 39.2% | 1.0 | 1,781 | 30.8% | 0.9 | 2,758 | 47.6% | 1.2 |
| Chronic neutrophilic leukemia | 30 | 0.3% | 0.0 | 23 | 0.4% | 0.0 | - | - | - |
| Hypereosinophilic syndrome | 148 | 1.3% | 0.0 | 93 | 1.6% | 0.0 | 55 | 0.9% | 0.0 |
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Chronic Myelomonocytic Leukemia (CMML) | 1,794 | 100.0% | 0.4 | 1,140 | 100.0% | 0.6 | 654 | 100.0% | 0.3 |
Footnotes:
Source: SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey and Georgia excluding ATL/RG).
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
- Statistic not shown due to fewer than 16 cases during the time period.
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