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Table 2.3

All Cancer Sites (Invasive)

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2008 With up to Five Joinpoints, 1992-2008 With up to Three Joinpoints,

Females by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2008
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 1999-08 2004-08
All Races 1975-79 -0.3 1979-87 1.6* 1987-95 0.1 1995-98 1.5 1998-05 -0.5* 2005-08 0.6 -0.2 0.3
White 1975-79 -0.2 1979-87 1.7* 1987-95 0.1 1995-98 1.8 1998-05 -0.5* 2005-08 0.5 -0.2 0.3
Black 1975-90 1.2* 1990-08 0.1                 0.1 0.1
SEER 13 Delay-Adjusted Incidenceb, 1992-2008
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 1999-08 2004-08
All Races 1992-98 0.8* 1998-06 -0.5* 2006-08 1.1             -0.2 0.3
White 1992-94 -0.3 1994-98 1.5* 1998-04 -0.7* 2004-08 0.3         -0.3 0.3
Black 1992-08 0.1                     0.1 0.1
SEER 9 Observed Incidencea, 1975-2008
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 1999-08 2004-08
All Races 1975-79 -0.3 1979-87 1.6* 1987-95 0.1 1995-98 1.3 1998-08 -0.4*     -0.4* -0.4*
White 1975-79 -0.2 1979-87 1.7* 1987-95 0.1 1995-98 1.6 1998-08 -0.5*     -0.5* -0.5*
Black 1975-91 1.1* 1991-08 0.0                 0.0 0.0
SEER 13 Observed Incidenceb, 1992-2008
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 1999-08 2004-08
All Races 1992-94 -0.4 1994-98 1.2 1998-04 -0.8* 2004-08 0.0         -0.4* 0.0
White 1992-94 -0.3 1994-98 1.4* 1998-04 -0.8* 2004-08 -0.1         -0.5* -0.1
White NHe f 1992-98 1.1* 1998-08 -0.4*                 -0.4* -0.4*
Black 1992-08 -0.1                     -0.1 -0.1
Black NHe f 1992-08 0.0                     0.0 0.0
APIe 1992-08 0.3*                     0.3* 0.3*
AI/ANe g 1992-08 0.7*                     0.7* 0.7*
Hispanicf 1992-08 0.1                     0.1 0.1
U.S. Cancer Mortalityc, 1975-2008
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 1999-08 2004-08
All Races 1975-91 0.6* 1991-01 -0.6* 2001-08 -1.5*             -1.3* -1.5*
White 1975-90 0.6* 1990-94 -0.2 1994-02 -0.8* 2002-08 -1.4*         -1.2* -1.4*
Black 1975-92 1.0* 1992-02 -0.9* 2002-08 -1.8*             -1.5* -1.8*
U.S. Cancer Mortalityc, 1992-2008
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 1999-08 2004-08
All Races 1992-02 -0.7* 2002-08 -1.6*                 -1.3* -1.6*
White 1992-01 -0.6* 2001-08 -1.4*                 -1.2* -1.4*
White NHe f 1992-94 0.3 1994-98 -1.0* 1998-01 -0.1 2001-08 -1.3*         -1.1* -1.3*
Black 1992-02 -0.8* 2002-08 -1.8*                 -1.5* -1.8*
Black NHe f 1992-03 -0.7* 2003-08 -2.0*                 -1.4* -2.0*
APIe 1992-08 -1.0*                     -1.0* -1.0*
AI/ANe g 1992-08 0.0                     0.0 0.0
Hispanicf 1992-01 -0.3 2001-08 -1.6*                 -1.3* -1.6*

Footnotes:

Joinpoint Regression Program Version 3.5, April 2011, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. The Hispanic and Non-Hispanic mortality trends exclude deaths from CT, DC, ME, MD, MN, NH, NY, ND, OK and VT.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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