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Table 16.2

Melanoma of the Skin (Invasive)

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2010 With up to Five Joinpoints, 1992-2010 With up to Three Joinpoints,

Males by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2010
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2001-10 2006-10
All Races 1975-86 5.6* 1986-10 2.9*                 2.9* 2.9*
White 1975-86 5.9* 1986-10 3.2*                 3.2* 3.2*
Black - -                     - -
SEER 13 Delay-Adjusted Incidenceb, 1992-2010
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2001-10 2006-10
All Races 1992-10 2.4*                     2.4* 2.4*
White 1992-10 2.8*                     2.8* 2.8*
Black - -                     - -
SEER 9 Observed Incidencea, 1975-2010
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2001-10 2006-10
All Races 1975-86 5.6* 1986-10 2.9*                 2.9* 2.9*
White 1975-86 5.9* 1986-10 3.1*                 3.1* 3.1*
Black 1975-10 0.1                     0.1 0.1
SEER 13 Observed Incidenceb, 1992-2010
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2001-10 2006-10
All Races 1992-10 2.4*                     2.4* 2.4*
White 1992-10 2.8*                     2.8* 2.8*
White NHe f 1992-10 3.1*                     3.1* 3.1*
Black 1992-95 75.1* 1995-04 -8.1* 2004-10 5.7             0.9 5.7
Black NHe f 1992-95 75.7* 1995-04 -7.8* 2004-10 5.5             0.9 5.5
APIe 1992-10 1.1                     1.1 1.1
AI/ANe g 1992-10 2.0                     2.0 2.0
Hispanicf 1992-10 1.3*                     1.3* 1.3*
U.S. Cancer Mortalityc, 1975-2010
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2001-10 2006-10
All Races 1975-89 2.2* 1989-10 0.3*                 0.3* 0.3*
White 1975-90 2.4* 1990-02 0.1 2002-10 1.0*             0.9* 1.0*
Black 1975-10 -0.7*                     -0.7* -0.7*
U.S. Cancer Mortalityc, 1992-2010
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2001-10 2006-10
All Races 1992-10 0.4*                     0.4* 0.4*
White 1992-10 0.5*                     0.5* 0.5*
White NHe f 1992-10 0.7*                     0.7* 0.7*
Black 1992-10 0.3                     0.3 0.3
Black NHe f 1992-10 0.0                     0.0 0.0
APIe 1992-10 -1.1                     -1.1 -1.1
AI/ANe g 1992-10 4.8*                     4.8* 4.8*
Hispanicf 1992-10 0.2                     0.2 0.2

Footnotes:

Joinpoint Regression Program Version 4.0.3, April 2013, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. The Hispanic and Non-Hispanic mortality trends exclude deaths from CT, DC, ME, MD, MN, NH, NY, ND, SC, OK and VT.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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