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Table 1.8

SEER Incidence and U.S. Mortality Trends (APC) by Primary Cancer Site and Sex
All Races, 2002-2011
Site Incidencea US Mortalityb
Both Sexes Males Females Both Sexes Males Females
All Sites -0.6* -1.2* -0.2 -1.5* -1.8* -1.4*
Oral Cavity & Pharynx: 0.4* 0.4* 0.1 -1.0* -0.9* -1.5*
Lip -3.5* -4.1* -2.1* -1.8 -1.8 -2.0
Tongue 1.8* 2.2* 0.9 -0.8* -0.6* -1.4*
Salivary gland 0.5 0.4 0.3 -0.1 0.0 -0.6
Floor of mouth -3.2* -3.5* -2.2 -8.2* -8.9* -5.8*
Gum & other oral cavity -0.5 -0.8 0.0 -1.6* -1.7* -1.4*
Nasopharynx -0.9 -0.8 -1.3 -1.1* -0.6 -2.5*
Tonsil 2.9* 3.1* 1.9* 1.2* 1.5* -0.3
Oropharynx 2.6* 3.0* 1.3 1.4* 1.0 1.8
Hypopharynx -2.5* -2.7* -2.2* -2.8* -2.9* -2.2
Other oral cavity & pharynx -0.8 -0.5 -2.5 -2.4* -2.1* -3.7*
Digestive System: -1.2* -1.2* -1.3* -1.1* -1.0* -1.3*
Esophagus -0.9* -0.7 -2.2* -0.7* -0.6* -1.6*
Stomach -1.3* -1.6* -1.0* -2.9* -3.2* -2.7*
Small intestine 1.8* 1.4* 2.3* 0.1 0.2 -0.2
Colon & Rectum: -2.8* -3.0* -2.6* -2.9* -3.0* -2.9*
Colon -3.1* -3.4* -2.9* - - -
Rectum -2.0* -2.2* -1.9* - - -
Anus, anal canal & anorectum 1.9* 1.3 2.4* 3.6* 4.2* 3.3*
Liver & intrahepatic bile duct 3.4* 3.7* 2.5* 2.5* 2.6* 1.8*
Gallbladder -0.2 -0.4 -0.1 -0.9* -0.2 -1.2*
Other biliary 1.0* 1.5* 0.2 -2.1* -2.4* -1.9*
Pancreas 0.7* 0.9* 0.6* 0.4* 0.3* 0.4*
Retroperitoneum -1.0 -0.6 -1.6 -2.3* -2.3 -2.4*
Peritoneum, omentum & mesentery -1.2 0.1 -1.2 0.6 1.6 0.4
Other digestive system 1.8* 2.5* 1.2 0.2 0.5 0.0
Respiratory System: -1.7* -2.3* -1.0* -2.0* -2.6* -1.3*
Nose, nasal cavity & middle ear -0.4 -0.4 -0.5 -1.1 -1.6 -0.3
Larynx -1.9* -2.1* -1.8* -2.3* -2.6* -2.1*
Lung & bronchus -1.7* -2.4* -1.0* -1.9* -2.6* -1.2*
Pleura -3.1 -2.1 - -5.5* -5.6* -5.9*
Trachea & other respiratory organs -1.1 -0.6 -1.9 -3.8* -4.1* -3.5
Bones & joints -0.1 -0.1 -0.2 0.0 0.2 -0.2
Soft tissue (including heart) 0.8* 0.8* 0.8 0.7* 1.1* 0.3
Skin (excl. basal & squamous): 1.3* 1.7* 0.8 0.5* 0.8* -0.3
Melanoma of the skin 1.4* 1.6* 0.9 0.4 0.7* -0.3
Other non-epithelial skin 1.2 1.9* 0.0 1.0* 1.2* -0.1
Breast -0.3 1.8* -0.2 -2.1* -0.3 -2.0*
Breast (in situ) 0.9* 2.6 1.1* - - -
Female Genital System: -0.1 - 0.0 -1.2* - -1.0*
Cervix uteri -1.7* - -1.6* -1.3* - -1.1*
Corpus uteri 1.0* - 1.2* -0.7* - -0.4
Uterus, NOS 2.8* - 3.3* 1.4* - 1.8*
Ovaryc -1.9* - -1.7* -2.2* - -2.0*
Vagina 0.2 - 0.5 -1.0* - -0.7
Vulva 0.9* - 1.1* 0.9* - 1.4*
Other female genital system 5.6* - 5.6* 1.7 - 1.9
Male Genital System: -1.7* -2.2* - -2.6* -3.3* -
Prostate -1.9* -2.3* - -2.6* -3.3* -
Testis 0.6* 0.6* - -0.5 -0.6 -
Penis 0.8 0.4 - -0.9 -1.1 -
Other male genital system 0.7 0.6 - 3.2 2.7 -
Urinary System: 0.3 0.1 0.4 -0.3* -0.3* -0.9*
Urinary bladder -0.8* -0.8* -1.2* 0.1 0.1 -0.6*
Kidney & renal pelvis 1.9* 1.8* 1.8* -0.9* -0.8* -1.2*
Ureter -0.2 -0.3 -0.4 -0.5 -0.4 -0.9
Other urinary system 2.2* 2.0 2.5 1.5 2.6 -0.4
Eye & Orbit -0.9* -1.3* -0.5 0.8 0.1 1.2
Brain & Nervous System:d -0.6* -0.5* -0.7* -0.4 -0.4 -0.5*
Brain -0.5 -0.5 -0.6 - - -
Cranial nerves & other nervous system -1.6 -1.2 -1.8 - - -
Endocrine System: 5.5* 4.7* 5.8* 0.7* 1.0* 0.4
Thyroid 5.8* 5.3* 6.0* 1.3* 1.8* 0.9
Other endocrine & thymus 0.7 0.2 0.9 -0.3 -0.2 -0.5
Lymphoma: -0.2 -0.1 -0.3 -2.6* -2.3* -3.0*
Hodgkin lymphoma -0.4 -0.3 -0.5 -2.8* -2.4* -3.5*
Non-Hodgkin lymphoma -0.1 0.0 -0.3 -2.6* -2.3* -3.0*
Myeloma 0.7* 0.7* 0.6 -1.5* -1.3* -1.9*
Leukemia: 0.0 -0.3 0.1 -0.9* -1.0* -1.0*
Lymphocytic: -0.4 -0.7* -0.1 -1.5* -1.6* -1.5*
Acute lymphocytic 1.1* 0.6 1.8* -1.2* -1.7* -0.5
Chronic lymphocytic -0.9* -1.1* -0.8 -1.6* -1.6* -1.9*
Other lymphocytic -1.2 -1.1 -2.1 -1.0 -1.5* -1.1
Myeloid & Monocytic: 0.9* 0.8* 0.9* -0.2 -0.3 -0.4
Acute myeloid 1.3* 0.9 1.7* 0.3* 0.3 0.1
Chronic myeloid 1.0* 1.1* 0.5 -4.4* -4.2* -4.7*
Acute monocytic -3.1* -2.1 -4.1* -3.8* -4.9* -3.2
Other myeloid & monocytic -1.2 0.8 -3.8* 0.3 -0.2 0.2
Other leukemia: -4.1* -4.2* -4.1* -1.6* -1.6* -1.8*
Other acute leukemia -4.6* -4.4* -5.1* -4.1* -4.4* -4.1*
Aleukemic, subleukemic & NOS -3.7* -4.1* -3.3 0.1 0.3 -0.1
Kaposi Sarcomae -3.1* -3.3* -1.7 - - -
Mesotheliomae -1.0 -1.3 -0.4 - - -
Ill-defined & unspecified -2.8* -2.5* -3.1* -2.2* -2.1* -2.4*

Footnotes:

The APC is the Annual Percent Change over the time interval. Trends are based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey and Georgia excluding ATL/RG).

b US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

c Ovary excludes borderline cases or histologies 8442, 8451, 8462, 8472, and 8473.

d Due to coding changes, Brain & Nervous System mortality are no longer shown separately.

e Trend not shown for mortality. Category did not exist in mortality coding until 1999.

* The APC is significantly different from zero (p<.05).

- Statistic could not be calculated. Trend based on less than 10 cases for at least one year within the time interval.

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