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Figure 14.1
Figure 14.1
SEER Observed Incidence and Delay Adjusted Incidence Rates a
Cancer of the Liver and Intrahepatic Bile Duct, by Race and Sex
- Rates per 100,000 for Liver & Intrahepatic Bile Duct, White, Male, 1975-2010, All Ages
- Rates per 100,000 for Liver & Intrahepatic Bile Duct, Black, Male, 1975-2010, All Ages
- Rates per 100,000 for Liver & Intrahepatic Bile Duct, White, Female, 1975-2010, All Ages
- Rates per 100,000 for Liver & Intrahepatic Bile Duct, Black, Female, 1975-2010, All Ages
- Annual Percent Changes for the most recent trend in the data series as calculated by Joinpoint.
| Year | Delay-Adjusted SEER Incidence | Delay-Adjusted SEER Incidence Modeled (from Joinpoint) | Observed SEER Incidence | Observed SEER Incidence Modeled (from Joinpoint) | U.S. Mortality | U.S. Mortality Modeled (from Joinpoint) |
|---|---|---|---|---|---|---|
| 1975 | 3.2 | 3.2 | 3.2 | 3.2 | 3.5 | 3.4 |
| 1976 | 3.2 | 3.3 | 3.2 | 3.3 | 3.5 | 3.4 |
| 1977 | 3.6 | 3.3 | 3.6 | 3.3 | 3.4 | 3.5 |
| 1978 | 3.3 | 3.4 | 3.3 | 3.4 | 3.5 | 3.5 |
| 1979 | 3.3 | 3.4 | 3.3 | 3.4 | 3.5 | 3.6 |
| 1980 | 3.3 | 3.5 | 3.3 | 3.5 | 3.5 | 3.6 |
| 1981 | 3.9 | 3.5 | 3.9 | 3.6 | 3.8 | 3.7 |
| 1982 | 3.5 | 3.6 | 3.5 | 3.6 | 3.8 | 3.7 |
| 1983 | 3.7 | 3.6 | 3.7 | 3.7 | 3.7 | 3.8 |
| 1984 | 3.4 | 3.7 | 3.4 | 3.7 | 3.8 | 3.8 |
| 1985 | 4.1 | 3.9 | 4.1 | 3.9 | 3.9 | 3.9 |
| 1986 | 3.9 | 4.0 | 3.9 | 4.1 | 4.1 | 4.0 |
| 1987 | 3.6 | 4.2 | 3.6 | 4.2 | 4.1 | 4.2 |
| 1988 | 4.3 | 4.4 | 4.3 | 4.4 | 4.4 | 4.4 |
| 1989 | 4.3 | 4.5 | 4.3 | 4.6 | 4.5 | 4.5 |
| 1990 | 4.7 | 4.7 | 4.7 | 4.7 | 4.7 | 4.7 |
| 1991 | 5.5 | 4.9 | 5.5 | 4.9 | 4.8 | 4.9 |
| 1992 | 4.8 | 5.1 | 4.8 | 5.1 | 5.2 | 5.1 |
| 1993 | 5.9 | 5.3 | 5.9 | 5.3 | 5.3 | 5.3 |
| 1994 | 5.6 | 5.6 | 5.6 | 5.6 | 5.4 | 5.5 |
| 1995 | 5.4 | 5.8 | 5.4 | 5.8 | 5.7 | 5.7 |
| 1996 | 6.8 | 6.0 | 6.8 | 6.0 | 5.9 | 5.9 |
| 1997 | 6.6 | 6.3 | 6.6 | 6.3 | 5.9 | 5.9 |
| 1998 | 7.0 | 6.5 | 7.0 | 6.5 | 6.1 | 6.0 |
| 1999 | 7.2 | 6.8 | 7.2 | 6.8 | 6.0 | 6.0 |
| 2000 | 7.1 | 7.1 | 7.1 | 7.0 | 6.1 | 6.2 |
| 2001 | 6.6 | 7.4 | 6.6 | 7.3 | 6.4 | 6.3 |
| 2002 | 7.0 | 7.7 | 7.0 | 7.6 | 6.5 | 6.5 |
| 2003 | 7.7 | 8.0 | 7.7 | 7.9 | 6.7 | 6.7 |
| 2004 | 8.0 | 8.4 | 8.0 | 8.2 | 6.7 | 6.8 |
| 2005 | 8.7 | 8.7 | 8.6 | 8.6 | 7.1 | 7.0 |
| 2006 | 9.3 | 9.1 | 9.2 | 8.9 | 7.0 | 7.2 |
| 2007 | 9.5 | 9.4 | 9.4 | 9.3 | 7.2 | 7.4 |
| 2008 | 9.8 | 9.8 | 9.7 | 9.7 | 7.6 | 7.6 |
| 2009 | 10.4 | 10.2 | 10.2 | 10.0 | 7.9 | 7.8 |
| 2010 | 10.5 | 10.7 | 10.3 | 10.5 | 8.0 | 8.0 |
| 2011 | 11.4 | 11.1 | 10.8 | 10.9 | 8.3 | 8.2 |
| Year | Delay-Adjusted SEER Incidence | Delay-Adjusted SEER Incidence Modeled (from Joinpoint) | Observed SEER Incidence | Observed SEER Incidence Modeled (from Joinpoint) | U.S. Mortality | U.S. Mortality Modeled (from Joinpoint) |
|---|---|---|---|---|---|---|
| 1975 | 6.5 | 5.6 | 6.5 | 5.0 | 6.3 | 6.7 |
| 1976 | 6.2 | 5.7 | 6.2 | 5.2 | 6.8 | 6.7 |
| 1977 | 5.0 | 5.9 | 5.0 | 5.4 | 7.2 | 6.8 |
| 1978 | 6.8 | 6.1 | 6.8 | 5.6 | 7.0 | 6.9 |
| 1979 | 7.1 | 6.3 | 7.1 | 5.8 | 6.6 | 6.9 |
| 1980 | 5.0 | 6.5 | 5.0 | 6.0 | 6.8 | 7.0 |
| 1981 | 7.1 | 6.6 | 7.1 | 6.3 | 6.7 | 7.0 |
| 1982 | 5.4 | 6.8 | 5.4 | 6.5 | 7.2 | 7.1 |
| 1983 | 6.3 | 7.0 | 6.3 | 6.8 | 7.3 | 7.1 |
| 1984 | 5.3 | 7.3 | 5.3 | 7.0 | 7.9 | 7.2 |
| 1985 | 7.5 | 7.5 | 7.5 | 7.3 | 7.2 | 7.2 |
| 1986 | 7.6 | 7.7 | 7.6 | 7.6 | 7.3 | 7.3 |
| 1987 | 7.7 | 7.9 | 7.7 | 7.9 | 6.9 | 7.3 |
| 1988 | 8.9 | 8.1 | 8.9 | 8.2 | 7.2 | 7.5 |
| 1989 | 9.1 | 8.4 | 9.1 | 8.5 | 8.0 | 7.7 |
| 1990 | 10.6 | 8.6 | 10.6 | 8.8 | 7.8 | 7.8 |
| 1991 | 9.2 | 8.9 | 9.2 | 9.1 | 8.0 | 8.0 |
| 1992 | 8.4 | 9.2 | 8.4 | 9.5 | 8.5 | 8.2 |
| 1993 | 10.1 | 9.4 | 10.1 | 9.8 | 8.1 | 8.4 |
| 1994 | 9.5 | 9.7 | 9.5 | 10.2 | 8.9 | 8.6 |
| 1995 | 8.6 | 10.0 | 8.6 | 10.6 | 9.3 | 8.8 |
| 1996 | 11.0 | 10.3 | 11.0 | 11.0 | 9.1 | 9.0 |
| 1997 | 11.4 | 10.6 | 11.4 | 11.4 | 8.9 | 9.2 |
| 1998 | 9.6 | 10.9 | 9.6 | 11.9 | 10.1 | 9.4 |
| 1999 | 12.2 | 11.5 | 12.2 | 12.3 | 8.8 | 9.6 |
| 2000 | 11.6 | 12.1 | 11.6 | 12.8 | 9.5 | 9.8 |
| 2001 | 13.8 | 12.7 | 13.8 | 13.3 | 9.1 | 10.0 |
| 2002 | 12.0 | 13.3 | 11.9 | 13.8 | 10.0 | 10.2 |
| 2003 | 12.6 | 14.0 | 12.5 | 14.3 | 10.3 | 10.5 |
| 2004 | 16.0 | 14.7 | 15.9 | 14.9 | 10.7 | 10.7 |
| 2005 | 15.0 | 15.5 | 14.9 | 15.5 | 11.2 | 10.9 |
| 2006 | 15.4 | 16.3 | 15.3 | 16.0 | 10.9 | 11.2 |
| 2007 | 17.7 | 17.1 | 17.6 | 16.7 | 11.3 | 11.4 |
| 2008 | 19.3 | 18.0 | 19.1 | 17.3 | 11.9 | 11.7 |
| 2009 | 19.5 | 18.9 | 19.2 | 18.0 | 12.2 | 12.0 |
| 2010 | 20.1 | 19.9 | 19.7 | 18.6 | 12.3 | 12.2 |
| 2011 | 19.9 | 21.0 | 19.0 | 19.4 | 12.8 | 12.5 |
| Year | Delay-Adjusted SEER Incidence | Delay-Adjusted SEER Incidence Modeled (from Joinpoint) | Observed SEER Incidence | Observed SEER Incidence Modeled (from Joinpoint) | U.S. Mortality | U.S. Mortality Modeled (from Joinpoint) |
|---|---|---|---|---|---|---|
| 1975 | 1.4 | 1.4 | 1.4 | 1.4 | 2.0 | 1.9 |
| 1976 | 1.6 | 1.5 | 1.6 | 1.5 | 1.9 | 1.9 |
| 1977 | 1.3 | 1.5 | 1.3 | 1.5 | 1.9 | 1.9 |
| 1978 | 1.4 | 1.5 | 1.4 | 1.5 | 1.8 | 1.9 |
| 1979 | 1.5 | 1.5 | 1.5 | 1.5 | 2.0 | 1.9 |
| 1980 | 1.6 | 1.5 | 1.6 | 1.5 | 1.9 | 1.9 |
| 1981 | 1.5 | 1.5 | 1.5 | 1.5 | 1.9 | 1.9 |
| 1982 | 1.6 | 1.5 | 1.6 | 1.5 | 1.9 | 2.0 |
| 1983 | 1.4 | 1.5 | 1.4 | 1.5 | 1.9 | 2.0 |
| 1984 | 1.6 | 1.6 | 1.6 | 1.6 | 2.0 | 2.0 |
| 1985 | 1.5 | 1.6 | 1.5 | 1.6 | 2.1 | 2.0 |
| 1986 | 1.7 | 1.6 | 1.7 | 1.6 | 2.0 | 2.0 |
| 1987 | 1.9 | 1.7 | 1.9 | 1.7 | 2.0 | 2.0 |
| 1988 | 1.6 | 1.8 | 1.6 | 1.8 | 2.1 | 2.1 |
| 1989 | 1.9 | 1.8 | 1.9 | 1.8 | 2.2 | 2.2 |
| 1990 | 1.9 | 1.9 | 1.9 | 1.9 | 2.2 | 2.2 |
| 1991 | 2.1 | 2.0 | 2.1 | 2.0 | 2.3 | 2.3 |
| 1992 | 1.9 | 2.1 | 1.9 | 2.1 | 2.4 | 2.4 |
| 1993 | 2.1 | 2.2 | 2.1 | 2.2 | 2.6 | 2.5 |
| 1994 | 2.1 | 2.2 | 2.1 | 2.2 | 2.6 | 2.6 |
| 1995 | 2.2 | 2.3 | 2.2 | 2.3 | 2.7 | 2.7 |
| 1996 | 2.6 | 2.4 | 2.6 | 2.4 | 2.7 | 2.8 |
| 1997 | 2.6 | 2.5 | 2.6 | 2.5 | 2.8 | 2.8 |
| 1998 | 2.6 | 2.6 | 2.6 | 2.6 | 2.7 | 2.7 |
| 1999 | 2.7 | 2.7 | 2.7 | 2.7 | 2.7 | 2.7 |
| 2000 | 2.8 | 2.7 | 2.8 | 2.7 | 2.7 | 2.7 |
| 2001 | 2.6 | 2.6 | 2.6 | 2.6 | 2.7 | 2.8 |
| 2002 | 2.6 | 2.5 | 2.6 | 2.5 | 2.8 | 2.8 |
| 2003 | 2.7 | 2.6 | 2.7 | 2.6 | 2.9 | 2.9 |
| 2004 | 2.7 | 2.8 | 2.7 | 2.8 | 3.0 | 2.9 |
| 2005 | 2.9 | 2.9 | 2.9 | 2.9 | 3.0 | 3.0 |
| 2006 | 3.0 | 3.0 | 2.9 | 3.0 | 3.1 | 3.0 |
| 2007 | 3.0 | 3.2 | 3.0 | 3.1 | 3.1 | 3.1 |
| 2008 | 3.5 | 3.3 | 3.4 | 3.2 | 3.0 | 3.2 |
| 2009 | 3.4 | 3.5 | 3.4 | 3.4 | 3.2 | 3.2 |
| 2010 | 3.5 | 3.6 | 3.5 | 3.5 | 3.3 | 3.3 |
| 2011 | 3.8 | 3.8 | 3.6 | 3.6 | 3.4 | 3.4 |
| Year | Delay-Adjusted SEER Incidence | Delay-Adjusted SEER Incidence Modeled (from Joinpoint) | Observed SEER Incidence | Observed SEER Incidence Modeled (from Joinpoint) | U.S. Mortality | U.S. Mortality Modeled (from Joinpoint) |
|---|---|---|---|---|---|---|
| 1975 | 3.2 | 2.0 | 3.2 | 2.1 | 2.7 | 2.5 |
| 1976 | 2.3 | 2.1 | 2.3 | 2.1 | 2.7 | 2.5 |
| 1977 | 2.2 | 2.2 | 2.2 | 2.2 | 2.5 | 2.6 |
| 1978 | 2.1 | 2.2 | 2.1 | 2.2 | 2.8 | 2.6 |
| 1979 | 1.8 | 2.3 | 1.8 | 2.3 | 2.7 | 2.7 |
| 1980 | 2.5 | 2.3 | 2.5 | 2.4 | 2.8 | 2.7 |
| 1981 | 2.5 | 2.4 | 2.5 | 2.4 | 2.7 | 2.8 |
| 1982 | 2.6 | 2.5 | 2.6 | 2.5 | 2.9 | 2.9 |
| 1983 | 2.3 | 2.5 | 2.3 | 2.6 | 3.0 | 2.9 |
| 1984 | 1.9 | 2.6 | 1.9 | 2.6 | 2.7 | 3.0 |
| 1985 | 1.3 | 2.7 | 1.3 | 2.7 | 2.7 | 3.0 |
| 1986 | 3.2 | 2.8 | 3.2 | 2.8 | 2.9 | 3.1 |
| 1987 | 3.7 | 2.8 | 3.7 | 2.8 | 3.2 | 3.1 |
| 1988 | 1.8 | 2.9 | 1.8 | 2.9 | 3.0 | 3.2 |
| 1989 | 2.6 | 3.0 | 2.6 | 3.0 | 3.1 | 3.3 |
| 1990 | 3.5 | 3.1 | 3.5 | 3.1 | 3.6 | 3.3 |
| 1991 | 3.5 | 3.2 | 3.5 | 3.2 | 3.5 | 3.4 |
| 1992 | 3.4 | 3.3 | 3.4 | 3.3 | 3.3 | 3.5 |
| 1993 | 3.1 | 3.4 | 3.1 | 3.4 | 3.6 | 3.5 |
| 1994 | 1.9 | 3.5 | 1.9 | 3.4 | 3.5 | 3.6 |
| 1995 | 3.9 | 3.6 | 3.9 | 3.5 | 4.1 | 3.7 |
| 1996 | 3.6 | 3.7 | 3.6 | 3.6 | 3.7 | 3.7 |
| 1997 | 4.5 | 3.8 | 4.5 | 3.7 | 3.9 | 3.7 |
| 1998 | 4.1 | 3.9 | 4.1 | 3.8 | 3.7 | 3.8 |
| 1999 | 4.4 | 4.0 | 4.4 | 3.9 | 3.8 | 3.8 |
| 2000 | 3.4 | 4.1 | 3.4 | 4.1 | 3.6 | 3.8 |
| 2001 | 3.4 | 4.2 | 3.4 | 4.2 | 4.1 | 3.9 |
| 2002 | 3.9 | 4.3 | 3.9 | 4.3 | 3.7 | 3.9 |
| 2003 | 4.0 | 4.4 | 4.0 | 4.4 | 4.0 | 3.9 |
| 2004 | 4.6 | 4.6 | 4.5 | 4.5 | 4.1 | 4.0 |
| 2005 | 5.0 | 4.7 | 5.0 | 4.6 | 3.8 | 4.0 |
| 2006 | 5.3 | 4.8 | 5.3 | 4.8 | 3.9 | 4.1 |
| 2007 | 4.5 | 5.0 | 4.5 | 4.9 | 3.8 | 4.1 |
| 2008 | 5.0 | 5.1 | 4.9 | 5.0 | 3.9 | 4.1 |
| 2009 | 5.8 | 5.3 | 5.8 | 5.2 | 4.3 | 4.2 |
| 2010 | 5.8 | 5.4 | 5.7 | 5.3 | 4.3 | 4.2 |
| 2011 | 5.3 | 5.6 | 5.0 | 5.5 | 4.5 | 4.2 |
| Data Series | Year Range for APC | APC |
|---|---|---|
| Delay-Adjusted SEER Incidence, White, Male | 1984-11 | 4.2* |
| Observed SEER Incidence, White, Male | 1984-11 | 4.0* |
| Delay-Adjusted SEER Incidence, Black, Male | 1998-11 | 5.2* |
| Observed SEER Incidence, Black, Male | 1975-11 | 3.8* |
| Delay-Adjusted SEER Incidence, White, Female | 2002-11 | 4.6* |
| Observed SEER Incidence, White, Female | 2002-11 | 4.1* |
| Delay-Adjusted SEER Incidence, Black, Female | 1975-11 | 2.8* |
| Observed SEER Incidence, Black, Female | 1975-11 | 2.8* |
Footnotes:
a Source: SEER 9 areas. Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103).
Regression lines and APCs are calculated using the Joinpoint Regression Program Version 4.1.0, April 2014, National Cancer Institute.
The APC is the Annual Percent Change for the regression line segments.
* The APC is significantly different from zero (p < 0.05).
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