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Table 8.2

Cancer of the Esophagus (Invasive)

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2012 With up to Five Joinpoints, 1992-2012 With up to Three Joinpoints,

Males by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-04 0.8* 2004-12 -1.3*                 -1.0* -1.3*
White 1975-04 1.7* 2004-12 -0.5                 -0.2 -0.5
Black 1975-86 1.2 1986-12 -4.9*                 -4.9* -4.9*
SEER 13 Delay-Adjusted Incidenceb, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-12 -0.2                     -0.2 -0.2
White 1992-12 0.7*                     0.7* 0.7*
Black 1992-12 -4.8*                     -4.8* -4.8*
SEER 9 Observed Incidencea, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-04 0.8* 2004-12 -1.4*                 -1.1* -1.4*
White 1975-04 1.7* 2004-12 -0.6                 -0.3 -0.6
Black 1975-86 1.3 1986-12 -4.9*                 -4.9* -4.9*
SEER 13 Observed Incidenceb, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-12 -0.2                     -0.2 -0.2
White 1992-01 2.0* 2001-12 -0.2                 -0.2 -0.2
White NHe f 1992-04 1.9* 2004-12 -0.6                 -0.3 -0.6
Black 1992-12 -4.9*                     -4.9* -4.9*
Black NHe f 1992-12 -4.9*                     -4.9* -4.9*
APIe 1992-12 -2.1*                     -2.1* -2.1*
AI/ANe g 1992-12 -3.2                     -3.2 -3.2
Hispanicf 1992-12 -1.1*                     -1.1* -1.1*
U.S. Cancer Mortalityc, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-85 0.7* 1985-94 1.2* 1994-05 0.4* 2005-12 -1.0*         -0.7* -1.0*
White 1975-82 0.3 1982-99 1.9* 1999-05 1.0* 2005-12 -0.5*         -0.2 -0.5*
Black 1975-84 0.8* 1984-93 -1.9* 1993-12 -4.7*             -4.7* -4.7*
U.S. Cancer Mortalityc, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-05 0.5* 2005-12 -1.1*                 -0.7* -1.1*
White 1992-05 1.4* 2005-12 -0.7*                 -0.2 -0.7*
White NHe f 1992-04 1.7* 2004-12 -0.4                 -0.1 -0.4
Black 1992-12 -4.6*                     -4.6* -4.6*
Black NHe f 1992-12 -4.5*                     -4.5* -4.5*
APIe 1992-12 -2.1*                     -2.1* -2.1*
AI/ANe g 1992-05 3.1* 2005-12 -6.2                 -4.2 -6.2
Hispanicf 1992-12 -0.8*                     -0.8* -0.8*

Footnotes:

Joinpoint Regression Program Version 4.2.0, April 2015, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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