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Table 13.2

Leukemia

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2012 With up to Five Joinpoints, 1992-2012 With up to Three Joinpoints,

Males by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-07 0.2* 2007-12 2.5*                 1.5* 2.5*
White 1975-98 0.1 1998-12 1.0*                 1.0* 1.0*
Black 1975-12 0.3*                     0.3* 0.3*
SEER 13 Delay-Adjusted Incidenceb, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-06 0.2 2006-12 1.8*                 1.3* 1.8*
White 1992-12 0.7*                     0.7* 0.7*
Black 1992-12 0.8*                     0.8* 0.8*
SEER 9 Observed Incidencea, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-12 0.1*                     0.1* 0.1*
White 1975-12 0.2*                     0.2* 0.2*
Black 1975-12 0.0                     0.0 0.0
SEER 13 Observed Incidenceb, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-12 0.1                     0.1 0.1
White 1992-12 0.1                     0.1 0.1
White NHe f 1992-12 0.2                     0.2 0.2
Black 1992-12 0.2                     0.2 0.2
Black NHe f 1992-12 0.3                     0.3 0.3
APIe 1992-12 -0.1                     -0.1 -0.1
AI/ANe g 1992-12 2.2                     2.2 2.2
Hispanicf 1992-12 0.2                     0.2 0.2
U.S. Cancer Mortalityc, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-80 0.5 1980-87 -0.7* 1987-95 0.1 1995-12 -0.9*         -0.9* -0.9*
White 1975-00 -0.3* 2000-12 -0.8*                 -0.8* -0.8*
Black 1975-91 1.0* 1991-12 -1.3*                 -1.3* -1.3*
U.S. Cancer Mortalityc, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-12 -0.8*                     -0.8* -0.8*
White 1992-12 -0.7*                     -0.7* -0.7*
White NHe f 1992-12 -0.7*                     -0.7* -0.7*
Black 1992-12 -1.3*                     -1.3* -1.3*
Black NHe f 1992-12 -1.2*                     -1.2* -1.2*
APIe 1992-12 -0.5                     -0.5 -0.5
AI/ANe g 1992-12 0.5                     0.5 0.5
Hispanicf 1992-12 -0.5*                     -0.5* -0.5*

Footnotes:

Joinpoint Regression Program Version 4.2.0, April 2015, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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