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Table 16.3

Melanoma of the Skin (Invasive)

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2012 With up to Five Joinpoints, 1992-2012 With up to Three Joinpoints,

Females by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-86 4.0* 1986-93 0.6 1993-96 5.6 1996-10 2.2* 2010-12 -2.9     1.1 -0.4
White 1975-81 6.2* 1981-93 2.1* 1993-05 3.5* 2005-12 0.9         1.4* 0.9
Black 1975-12 0.1                     0.1 0.1
SEER 13 Delay-Adjusted Incidenceb, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-05 2.4* 2005-12 0.5                 0.9* 0.5
White 1992-05 3.1* 2005-12 0.5                 1.1* 0.5
Black 1992-12 0.5                     0.5 0.5
SEER 9 Observed Incidencea, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-86 4.0* 1986-93 0.6 1993-96 5.6 1996-10 2.2* 2010-12 -3.7     0.8 -0.8
White 1975-81 6.2* 1981-93 2.1* 1993-05 3.5* 2005-12 0.6         1.2* 0.6
Black 1975-12 0.0                     0.0 0.0
SEER 13 Observed Incidenceb, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-97 4.0* 1997-10 1.6* 2010-12 -3.1             0.5 -0.8
White 1992-06 3.0* 2006-12 -0.2                 0.9 -0.2
White NHe f 1992-06 3.6* 2006-12 0.2                 1.3* 0.2
Black 1992-12 0.4                     0.4 0.4
Black NHe f 1992-12 0.5                     0.5 0.5
APIe 1992-12 0.0                     0.0 0.0
AI/ANe g 1992-12 2.1                     2.1 2.1
Hispanicf 1992-12 0.3                     0.3 0.3
U.S. Cancer Mortalityc, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-88 0.8* 1988-12 -0.5*                 -0.5* -0.5*
White 1975-86 1.1* 1986-12 -0.3*                 -0.3* -0.3*
Black 1975-12 -0.8*                     -0.8* -0.8*
U.S. Cancer Mortalityc, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-12 -0.5*                     -0.5* -0.5*
White 1992-12 -0.3*                     -0.3* -0.3*
White NHe f 1992-12 0.0                     0.0 0.0
Black 1992-12 -1.7*                     -1.7* -1.7*
Black NHe f 1992-12 -1.6*                     -1.6* -1.6*
APIe 1992-12 -0.3                     -0.3 -0.3
AI/ANe g - -                     - -
Hispanicf 1992-12 -0.4                     -0.4 -0.4

Footnotes:

Joinpoint Regression Program Version 4.2.0, April 2015, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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