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Table 26.1

Cancer of the Thyroid (Invasive)

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2012 With up to Five Joinpoints, 1992-2012 With up to Three Joinpoints,

Both Sexes by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-77 6.3 1977-80 -6.6 1980-97 2.4* 1997-09 6.7* 2009-12 2.3     5.2* 3.4*
White 1975-77 7.4 1977-80 -6.6 1980-97 2.7* 1997-09 7.1* 2009-12 1.4     5.2* 2.8*
Black 1975-95 0.8 1995-12 6.4*                 6.4* 6.4*
SEER 13 Delay-Adjusted Incidenceb, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-98 3.0* 1998-09 6.6* 2009-12 2.3*             5.1* 3.3*
White 1992-98 3.6* 1998-09 6.8* 2009-12 1.5             5.0* 2.8*
Black 1992-95 -4.1 1995-12 6.7*                 6.7* 6.7*
SEER 9 Observed Incidencea, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-77 6.3 1977-80 -6.6 1980-97 2.4* 1997-09 6.6* 2009-12 1.9     5.0* 3.0*
White 1975-77 7.4 1977-80 -6.7 1980-97 2.7* 1997-09 7.0* 2009-12 0.9     4.9* 2.4*
Black 1975-95 0.8 1995-12 6.2*                 6.2* 6.2*
SEER 13 Observed Incidenceb, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-98 3.0* 1998-09 6.5* 2009-12 1.9             4.9* 3.0*
White 1992-98 3.6* 1998-09 6.7* 2009-12 1.1             4.8* 2.5*
White NHe f 1992-98 4.4* 1998-09 7.0* 2009-12 0.9             4.9* 2.4*
Black 1992-95 -3.8 1995-12 6.5*                 6.5* 6.5*
Black NHe f 1992-95 -4.3 1995-12 6.7*                 6.7* 6.7*
APIe 1992-98 -0.7 1998-12 4.7*                 4.7* 4.7*
AI/ANe g 1992-12 3.9*                     3.9* 3.9*
Hispanicf 1992-95 -4.4 1995-12 4.9*                 4.9* 4.9*
U.S. Cancer Mortalityc, 1975-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1975-85 -2.7* 1985-03 0.3 2003-09 2.0* 2009-12 -2.3         0.6 -1.2
White 1975-88 -2.2* 1988-12 0.7*                 0.7* 0.7*
Black 1975-12 0.0                     0.0 0.0
U.S. Cancer Mortalityc, 1992-2012
Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2003-12 2008-12
All Races 1992-12 0.8*                     0.8* 0.8*
White 1992-12 0.7*                     0.7* 0.7*
White NHe f 1992-12 0.7*                     0.7* 0.7*
Black 1992-12 0.9*                     0.9* 0.9*
Black NHe f 1992-12 1.0*                     1.0* 1.0*
APIe 1992-12 -0.2                     -0.2 -0.2
AI/ANe g 1992-12 0.6                     0.6 0.6
Hispanicf 1992-12 0.0                     0.0 0.0

Footnotes:

Joinpoint Regression Program Version 4.2.0, April 2015, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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