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Table 2.2

All Cancer Sites (Invasive)

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2014 With up to Five Joinpoints, 1992-2014 With up to Four Joinpoints,

Males by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2014

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2005-14 2010-14
All Races 1975-89 1.3* 1989-92 5.2* 1992-95 -4.8* 1995-00 0.4 2000-09 -0.7* 2009-14 -2.7* -1.8* -2.7*
White 1975-89 1.4* 1989-92 5.0* 1992-95 -5.2* 1995-99 0.8 1999-08 -0.4* 2008-14 -2.4* -1.7* -2.4*
Black 1975-81 2.8* 1981-89 0.6 1989-92 6.8* 1992-05 -1.5* 2005-08 0.8 2008-14 -3.7* -2.2* -3.7*

SEER 13 Delay-Adjusted Incidenceb, 1992-2014

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2005-14 2010-14
All Races 1992-94 -5.7* 1994-09 -0.5* 2009-14 -3.1*             -2.0* -3.1*
White 1992-94 -6.3* 1994-08 -0.3* 2008-14 -2.7*             -1.9* -2.7*
Black 1992-10 -1.3* 2010-14 -4.3*                 -2.7* -4.3*

SEER 9 Observed Incidencea, 1975-2014

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2005-14 2010-14
All Races 1975-89 1.3* 1989-92 5.2* 1992-95 -4.8* 1995-00 0.4 2000-09 -0.7* 2009-14 -3.1* -2.1* -3.1*
White 1975-89 1.4* 1989-92 5.0* 1992-95 -5.1* 1995-00 0.7 2000-09 -0.7* 2009-14 -3.1* -2.0* -3.1*
Black 1975-81 2.9* 1981-89 0.6 1989-92 7.5* 1992-96 -2.6* 1996-09 -1.1* 2009-14 -4.3* -2.9* -4.3*

SEER 13 Observed Incidenceb, 1992-2014

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2005-14 2010-14
All Races 1992-94 -5.7* 1994-09 -0.5* 2009-14 -3.5*             -2.2* -3.5*
White 1992-94 -6.2* 1994-08 -0.3* 2008-14 -3.0*             -2.1* -3.0*
White NHe f 1992-94 -6.3* 1994-08 -0.2* 2008-14 -2.9*             -2.0* -2.9*
Black 1992-09 -1.3* 2009-14 -4.4*                 -3.1* -4.4*
Black NHe f 1992-09 -1.3* 2009-14 -4.3*                 -3.0* -4.3*
APIe 1992-95 -2.7 1995-07 -0.5* 2007-14 -3.0*             -2.5* -3.0*
AI/ANe g 1992-14 -0.6*                     -0.6* -0.6*
Hispanicf 1992-09 -0.5* 2009-14 -4.0*                 -2.5* -4.0*

U.S. Cancer Mortalityc, 1975-2014

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2005-14 2010-14
All Races 1975-79 1.0* 1979-90 0.3* 1990-93 -0.5 1993-01 -1.5* 2001-14 -1.8*     -1.8* -1.8*
White 1975-79 0.9* 1979-91 0.2* 1991-94 -0.8 1994-97 -1.8* 1997-00 -1.0* 2000-14 -1.7* -1.7* -1.7*
Black 1975-82 1.8* 1982-90 1.0* 1990-93 -0.2 1993-01 -2.0* 2001-14 -2.7*     -2.7* -2.7*

U.S. Cancer Mortalityc, 1992-2014

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2005-14 2010-14
All Races 1992-01 -1.4* 2001-14 -1.8*                 -1.8* -1.8*
White 1992-01 -1.3* 2001-14 -1.7*                 -1.7* -1.7*
White NHe f 1992-94 -0.2 1994-97 -1.8* 1997-00 -0.9 2000-14 -1.6*         -1.6* -1.6*
Black 1992-94 -0.5 1994-01 -2.1* 2001-14 -2.7*             -2.7* -2.7*
Black NHe f 1992-94 -0.1 1994-02 -2.1* 2002-14 -2.6*             -2.6* -2.6*
APIe 1992-14 -1.7*                     -1.7* -1.7*
AI/ANe g 1992-14 -0.3*                     -0.3* -0.3*
Hispanicf 1992-98 0.0 1998-14 -1.6*                 -1.6* -1.6*

Footnotes:

Joinpoint Regression Program Version 4.4, January 2017, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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