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Table 12.8

Cancer of the Larynx (Invasive)

5-Year Relative Survival (Percent) by Year of Diagnosis

Year of
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
1960-1963a - - - 53 54 46 - - -
1970-1973a - - - 62 63 56 - - -
1975-1977b 66.0 66.6 62.6 66.7 67.4 62.3 58.2 57.1 63.3g
1978-1980b 65.3 65.5 64.6 66.2 66.3 65.4 56.9 57.2 55.8g
1981-1983b 68.1 68.4 66.9 69.5 69.7 68.5 56.5 57.7 50.7g
1984-1986b 65.3 65.9 62.2 67.0 67.6 63.9 53.3 53.7 51.1g
1987-1989b 65.5 66.6 61.1 67.0 68.6 60.7 55.9 54.1 61.3g
1990-1992b 65.8 66.7 62.3 67.7 68.5 64.4 53.7 54.3 51.3g
1993-1995b 63.6 65.3 56.6 65.2 67.0 57.6 53.1 54.5 47.4g
1996-1998b 65.0 66.8 58.7 66.9 68.5 61.1 53.8 56.8 45.0g
1999-2001b 63.3 64.2 59.6 65.2 66.2 60.8 49.8 49.1 52.4g
2002-2006b 62.1 62.6 60.2 64.3 64.6 63.0 51.5 53.1 45.5
2007-2013b 62.6f 62.8f 61.5 64.5 64.6 64.2 50.2 50.9 47.8

5-Year Period Survival (Percent)cd

Year All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
2013 60.8 60.9 60.4 62.2 62.3 62.0 51.5 51.9 50.4

Stage Distribution (%) 2007-2013ce, Case Counts and Percentages

Stage at
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
Number of cases 16,335 13,222 3,113 13,099 10,622 2,477 2,491 1,959 532
Percent 100% 100% 100% 100% 100% 100% 100% 100% 100%
Localized 55 56 49 57 58 51 44 47 36
Regional 22 20 30 22 20 29 26 23 34
Distant 20 20 19 18 18 17 28 28 27
Unstaged 3 3 3 3 4 3 2 2 3

5-Year Relative Survival (Percent) 2007-2013c by Age at Diagnosis

Age at
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
Ages <45 74.4 71.2 82.3 78.5 75.8 84.9 54.7g 50.5g -
Ages 45-54 62.3 62.5 61.5 63.9 63.4 65.4 54.1 56.7 47.0
Ages 55-64 60.5 60.4 61.1 62.5 62.3 63.1 49.2 48.8 50.9
Ages 65-74 59.9 61.3 52.5 60.4 61.9 52.9 53.1 54.7 45.7g
Ages 75+ 58.3 60.7 48.3 58.9 61.5 47.8 49.7 50.1g 47.1g
Ages <65 62.0 61.7 63.3 64.0 63.5 66.2 51.1 51.3 50.2
Ages 65+ 59.1 60.9 50.7 59.7 61.6 50.8 52.1 53.5 46.0g

5-Year Relative Survival (Percent) 2007-2013c by Stage at Diagnosise

Stage at
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
All Stages 60.7 61.3 58.1 62.0 62.6 59.5 51.5 52.1 49.1
Localized 77.0 77.8 73.0 77.4 78.1 73.7 71.3 72.4 65.6
Regional 45.1 43.8 48.7 45.8 44.6 49.1 41.4 39.4 46.1
Distant 34.3 33.9 35.9 34.9 34.6 36.1 30.3 29.5 33.1
Unstaged 52.9 53.3 49.1g 55.0 55.5 51.0g 35.1g 35.6g -

Footnotes:

a Based on End Results data from a series of hospital registries and one population-based registry.

b SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta). Based on follow-up of patients into 2014.

c SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey and Georgia excluding ATL/RG). Based on follow-up of patients into 2014.

d Period survival provides a 2013 estimate of survival by piecing together the most recent conditional survival estimates from several cohorts. It is computed here using three year calendar blocks (2010-2012: 0-1 year survival), (2009-2011: 1-2 year survival), (2008-2010: 2-3 year survival), (2007-2009: 3-4 year survival), (2006-2008: 4-5 years survival).

e Stage at diagnosis is classified using SEER Summary Stage 2000. Stage distribution percentages may not sum to 100 due to rounding.

f The difference between 1975-1977 and 2007-2013 is statistically significant (p<.05).

g The standard error is between 5 and 10 percentage points.

h The standard error is greater than 10 percentage points.

- Statistic could not be calculated due to fewer than 25 cases during the time period.

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