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Table 1.9

SEER Incidence and U.S. Mortality Trends (APC) by Primary Cancer Site and Sex
Whites, 2006-2015

Site Incidencea US Mortalityb
Both Sexes Males Females Both Sexes Males Females
All Sites -1.2* -2.2* -0.2* -1.4* -1.6* -1.3*
Oral Cavity & Pharynx: 0.9* 1.1* 0.2 0.5 0.9* -0.6
Lip 0.2 -0.4 1.4 0.3 -1.2 2.4
Tongue 1.9* 2.3* 0.8 0.8 1.3* -0.4
Salivary gland -0.3 -0.6 -0.2 1.8* 2.4* 0.1
Floor of mouth -3.2* -3.6* -2.2 -6.3* -4.6* -9.5*
Gum & other oral cavity -0.1 -0.1 -0.1 0.7 1.2 -0.1
Nasopharynx -2.4* -2.1* -2.9* -2.1* -1.5* -3.3*
Tonsil 2.9* 3.1* 2.2* 2.8* 2.9* 1.6
Oropharynx 3.1* 3.5* 1.7 4.0* 4.3* 3.0*
Hypopharynx -2.6* -2.2* -4.2* -0.4 0.1 -2.6
Other oral cavity & pharynx 4.1* 5.4* -0.5 -2.2* -2.0* -3.3*
Digestive System: -1.0* -1.1* -1.0* -0.6* -0.6* -0.8*
Esophagus -0.7* -0.9* -0.9 -0.5* -0.6* -1.2*
Stomach -0.6* -0.9* -0.3 -2.0* -2.4* -1.7*
Small intestine 1.6* 1.0 2.4* 0.6 0.8 0.3
Colon & Rectum: -2.6* -2.9* -2.4* -2.3* -2.4* -2.4*
Colon -2.9* -3.2* -2.7* - - -
Rectum -1.9* -2.0* -1.8* - - -
Anus, anal canal & anorectum 1.7* 0.4 2.6* 2.9* 3.2* 2.8*
Liver & intrahepatic bile duct 3.1* 2.8* 3.8* 2.8* 2.7* 2.7*
Gallbladder -0.2 0.6 -0.5 -1.3* -1.3 -1.2*
Other biliary 0.2 0.2 -0.1 -0.8* -1.2* -0.5
Pancreas 0.6* 0.6* 0.6* 0.2* 0.2* 0.1
Retroperitoneum -1.5* -1.4 -1.6 -0.8 -0.6 -1.2
Peritoneum, omentum & mesentery -4.2* -4.9 -4.0* -0.2 2.8* -0.6
Other digestive system 5.2* 5.4* 4.8* 2.7* 2.5* 2.6*
Respiratory System: -2.4* -3.0* -1.8* -2.5* -3.1* -1.9*
Nose, nasal cavity & middle ear -0.9 -0.7 -1.2* -2.0 -1.3 -3.5*
Larynx -2.7* -2.9* -2.5* -2.0* -2.0* -2.8*
Lung & bronchus -2.4* -3.1* -1.7* -2.5* -3.2* -1.9*
Pleura -0.9 -2.2 - 1.0 0.7 1.1
Trachea & other respiratory organs -1.0 -0.1 -2.6* -0.3 -0.3 -0.6
Bones & joints 0.6 0.3 1.1 0.3 0.7 -0.2
Soft tissue (including heart) 0.7 0.3 0.9 0.3* 0.6 0.0
Skin (excl. basal & squamous): 1.5* 1.5* 1.3* 0.0 0.1 -0.4
Melanoma of the skin 1.5* 1.6* 1.3* -0.8 -0.9* -0.9*
Other non-epithelial skin 0.9 0.9 0.6 2.6* 2.6* 1.6*
Breast -0.1 0.1 0.0 -1.8* -0.8 -1.6*
Breast (in situ) -0.8 -0.4 -0.6 - - -
Female Genital System: -0.1 - 0.1 -1.0* - -0.8*
Cervix uteri -1.3* - -1.2* -0.3 - -0.2
Corpus uteri 0.9* - 1.1* 0.3 - 0.6
Uterus, NOS 4.7* - 5.1* 1.8* - 2.2*
Ovaryc -2.1* - -1.9* -2.7* - -2.5*
Vagina -1.1 - -0.8 -0.5 - -0.1
Vulva 0.9* - 1.1* 0.9* - 1.3*
Other female genital system 7.0* - 7.1* 6.1* - 6.4*
Male Genital System: -5.8* -6.1* - -2.1* -2.8* -
Prostate -6.2* -6.5* - -2.2* -2.9* -
Testis 0.8* 0.7* - 0.7 0.6 -
Penis 1.2 0.9 - 1.2 0.8 -
Other male genital system 1.3 0.7 - 2.6 2.1 -
Urinary System: -0.5* -0.7* -0.5 -0.2* -0.2* -0.9*
Urinary bladder -1.3* -1.5* -1.4* 0.0 -0.2 -0.3
Kidney & renal pelvis 0.5* 0.5 0.4 -0.5* -0.3* -1.4*
Ureter -1.7* -1.8* -2.0 0.0 0.5 -0.4
Other urinary system 3.8* 3.2* 4.7* -0.2 -0.6 -0.2
Eye & Orbit 0.7 0.7 0.5 2.0* 2.8* 1.2
Brain & Nervous System:d -0.4 -0.5* -0.2 0.6* 0.6* 0.6*
Brain -0.4 -0.6 -0.1 - - -
Cranial nerves & other nervous system -0.5 0.4 -1.4 - - -
Endocrine System: 3.0* 2.9* 3.1* -0.1 0.7* -0.7*
Thyroid 3.2* 3.4* 3.2* 0.1 0.9* -0.6
Other endocrine & thymus -0.9 -1.4 -0.4 -0.3 0.4 -1.0*
Lymphoma: -0.8* -0.7* -1.0* -2.3* -2.0* -2.8*
Hodgkin lymphoma -2.1* -2.0* -2.2* -3.8* -3.3* -4.4*
Non-Hodgkin lymphoma -0.7* -0.5* -0.8* -2.2* -1.9* -2.7*
Myeloma 1.3* 1.2* 1.2* -0.4 -0.4 -0.7*
Leukemia: 0.2 0.2 0.1 -1.1* -1.1* -1.3*
Lymphocytic: -0.6 -0.6 -0.7 -1.7* -1.7* -2.1*
Acute lymphocytic 0.7 0.8* 0.5 -0.9* -0.5 -1.5*
Chronic lymphocytic -1.0* -1.0* -1.3* -2.0* -2.0* -2.4*
Other lymphocytic -1.1 -1.5* -0.5 -1.8* -2.0* -1.3
Myeloid & Monocytic: 1.6* 1.6* 1.4* -0.1 -0.2 -0.3
Acute myeloid 2.3* 2.4* 2.1* -0.2 -0.2 -0.3
Chronic myeloid 1.2* 1.2* 1.0 -0.6 -0.6 -0.9
Acute monocytic -5.4* -5.3* -5.8* -1.9 -2.6 -1.6
Other myeloid & monocytic -1.3 -1.5 -1.5 1.2* 1.0* 0.9
Other leukemia: -4.3* -4.3* -4.6* -2.5* -2.4* -2.8*
Other acute leukemia -1.1 -2.1 -0.3 -4.9* -4.9* -5.0*
Aleukemic, subleukemic & NOS -6.6* -6.0* -7.5* -1.1 -1.0 -1.4*
Kaposi Sarcomae -3.9* -4.2* -2.1 - - -
Mesotheliomae -1.5* -1.9* -0.8 - - -
Ill-defined & unspecified -2.7* -2.6* -2.7* -1.7* -1.7* -1.7*

Footnotes:

The APC is the Annual Percent Change over the time interval. Trends are based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey and Georgia excluding ATL/RG).

b US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

c Ovary excludes borderline cases or histologies 8442, 8451, 8462, 8472, and 8473.

d Due to coding changes, Brain & Nervous System mortality are no longer shown separately.

e Trend not shown for mortality. Category did not exist in mortality coding until 1999.

* The APC is significantly different from zero (p<.05).

- Statistic could not be calculated. Trend based on less than 10 cases for at least one year within the time interval.

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