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Table 6.2

Cancer of the Colon and Rectum (Invasive)

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2015 With up to Five Joinpoints, 1992-2015 With up to Four Joinpoints,

Males by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1975-85 1.1* 1985-91 -1.2* 1991-95 -3.2* 1995-98 2.1 1998-15 -2.9*     -2.9* -2.9*
White 1975-86 1.1* 1986-95 -2.3* 1995-98 1.4 1998-07 -2.9* 2007-12 -4.1* 2012-15 -0.5 -2.8* -1.4
Black 1975-80 4.5 1980-02 0.0 2002-15 -2.7*             -2.7* -2.7*

SEER 13 Delay-Adjusted Incidenceb, 1992-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1992-95 -2.6* 1995-98 1.4 1998-08 -2.5* 2008-12 -3.9* 2012-15 -1.1     -2.6* -1.8*
White 1992-95 -2.8* 1995-98 1.5 1998-08 -2.7* 2008-12 -4.3* 2012-15 -0.4     -2.7* -1.4*
Black 1992-03 0.0 2003-15 -3.0*                 -3.0* -3.0*

SEER 9 Observed Incidencea, 1975-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1975-86 1.1* 1986-95 -2.2* 1995-98 1.5 1998-15 -2.9*         -2.9* -2.9*
White 1975-86 1.1* 1986-95 -2.3* 1995-98 1.4 1998-08 -2.9* 2008-11 -4.9* 2011-15 -1.5* -3.0* -1.5*
Black 1975-80 4.4 1980-02 0.1 2002-15 -2.9*             -2.9* -2.9*

SEER 13 Observed Incidenceb, 1992-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1992-95 -2.6* 1995-98 1.4 1998-08 -2.5* 2008-12 -3.9* 2012-15 -1.4*     -2.8* -2.1*
White 1992-95 -2.8* 1995-98 1.5 1998-08 -2.7* 2008-12 -4.3* 2012-15 -0.8     -2.8* -1.7*
White NHe f 1992-95 -2.9* 1995-98 1.6 1998-08 -2.9* 2008-12 -4.5* 2012-15 -0.3     -2.8* -1.4*
Black 1992-04 -0.2 2004-15 -3.4*                 -3.4* -3.4*
Black NHe f 1992-04 -0.1 2004-15 -3.3*                 -3.3* -3.3*
APIe 1992-01 -0.3 2001-15 -2.5*                 -2.5* -2.5*
AI/ANe g 1992-15 -0.2                     -0.2 -0.2
Hispanicf 1992-98 1.6 1998-08 -0.9 2008-15 -2.9*             -2.4* -2.9*

U.S. Cancer Mortalityc, 1975-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1975-79 0.6 1979-87 -0.6* 1987-02 -1.9* 2002-05 -4.1* 2005-15 -2.5*     -2.5* -2.5*
White 1975-79 0.6 1979-87 -0.8* 1987-02 -2.1* 2002-05 -4.3* 2005-15 -2.4*     -2.4* -2.4*
Black 1975-90 1.2* 1990-02 -0.7* 2002-15 -2.8*             -2.8* -2.8*

U.S. Cancer Mortalityc, 1992-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1992-02 -2.0* 2002-05 -4.0* 2005-15 -2.5*             -2.5* -2.5*
White 1992-02 -2.1* 2002-05 -4.1* 2005-12 -2.6* 2012-15 -1.8*         -2.3* -2.0*
White NHe f 1992-02 -2.1* 2002-05 -4.3* 2005-15 -2.5*             -2.5* -2.5*
Black 1992-02 -0.7* 2002-15 -2.8*                 -2.8* -2.8*
Black NHe f 1992-02 -0.7* 2002-15 -2.7*                 -2.7* -2.7*
APIe 1992-15 -1.9*                     -1.9* -1.9*
AI/ANe g 1992-15 0.3                     0.3 0.3
Hispanicf 1992-99 0.5 1999-15 -1.6*                 -1.6* -1.6*

Footnotes:

Joinpoint Regression Program Version 4.6, February 2018, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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