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Table 30.1
Myelodysplastic Syndromes, Chronic Myeloproliferative Disorders, and Chronic Myelomonocytic Leukemia
Counts, Percents and Age-Adjusted Incidence Ratesa by Subtype
18 SEER Geographic Areas 2011-2015
All Myelodysplastic syndromes (MDS),
Chronic myeloproliferative disorders (CMD),
Chronic myelomonocytic leukemia (CMML)
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Total | 35,678 | 100.0% | 7.8 | 19,550 | 100.0% | 9.9 | 16,128 | 100.0% | 6.3 |
Myelodysplastic Syndromes (MDS)
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Myelodysplastic Syndromes (MDS) | 20,934 | 100.0% | 4.6 | 12,051 | 100.0% | 6.3 | 8,883 | 100.0% | 3.4 |
| Refractory anemia (RA), NOS | 1,361 | 6.5% | 0.3 | 756 | 6.3% | 0.4 | 605 | 6.8% | 0.2 |
| RA with ringed sideroblasts | 1,283 | 6.1% | 0.3 | 717 | 5.9% | 0.4 | 566 | 6.4% | 0.2 |
| RA with excess blasts (RAEB) | 3,364 | 16.1% | 0.7 | 2,057 | 17.1% | 1.1 | 1,307 | 14.7% | 0.5 |
| RAEB in transformation | - | - | - | - | - | - | - | - | - |
| Refractory cytopenia w/multilineage dysplasia | 1,638 | 7.8% | 0.4 | 1,099 | 9.1% | 0.6 | 539 | 6.1% | 0.2 |
| Myelodysplastic syndrome with 5q deletion | 739 | 3.5% | 0.2 | 282 | 2.3% | 0.1 | 457 | 5.1% | 0.2 |
| Therapy-related myelodysplastic syndrome | - | - | - | - | - | - | - | - | - |
| Myelodysplastic syndrome, NOS | 12,549 | 59.9% | 2.8 | 7,140 | 59.2% | 3.8 | 5,409 | 60.9% | 2.0 |
Chronic Myeloproliferative Disorders (CMD)
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Chronic Myeloproliferative Disorders (CMD) | 12,702 | 100.0% | 2.7 | 6,202 | 100.0% | 2.9 | 6,500 | 100.0% | 2.6 |
| Polycythemia vera | 5,332 | 42.0% | 1.1 | 2,985 | 48.1% | 1.4 | 2,347 | 36.1% | 0.9 |
| Chronic myeloproliferative disease, NOS | - | - | - | - | - | - | - | - | - |
| Myelosclerosis with myeloid metaplasia | 1,641 | 12.9% | 0.4 | 974 | 15.7% | 0.5 | 667 | 10.3% | 0.3 |
| Essential thrombocythemia | 5,557 | 43.7% | 1.2 | 2,141 | 34.5% | 1.0 | 3,416 | 52.6% | 1.4 |
| Chronic neutrophilic leukemia | 40 | 0.3% | 0.0 | 22 | 0.4% | 0.0 | 18 | 0.3% | 0.0 |
| Hypereosinophilic syndrome | 132 | 1.0% | 0.0 | 80 | 1.3% | 0.0 | 52 | 0.8% | 0.0 |
Chronic Myelomonocytic Leukemia (CMML)
| Site | Both Sexes | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Count | Percent | Rate | Count | Percent | Rate | Count | Percent | Rate | |
| Chronic Myelomonocytic Leukemia (CMML) | 2,042 | 100.0% | 0.5 | 1,297 | 100.0% | 0.7 | 745 | 100.0% | 0.3 |
Footnotes:
Source: SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey and Georgia excluding ATL/RG).
a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
- Statistic not shown due to fewer than 16 cases during the time period.
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