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Table 5.3

Cancer of the Cervix Uteri (Invasive)

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2016 With up to Five Joinpoints, 2000-2016 With up to Three Joinpoints,

Ages 50+ by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2016

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16
All Races 1975-83 -4.9* 1983-91 -0.9 1991-06 -3.3* 2006-16 -1.1*         -1.1* -1.1*
White 1975-85 -4.6* 1985-91 0.2 1991-05 -3.4* 2005-16 -0.7         -0.7 -0.7
Black 1975-16 -3.9*                     -3.9* -3.9*

SEER 21 Delay-Adjusted Incidenceb, 2000-2016

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16
All Races 2000-03 -5.2* 2003-16 -1.6*                 -1.6* -1.6*
White 2000-16 -1.7*                     -1.7* -1.7*
White NHe f 2000-03 -5.4* 2003-16 -0.9*                 -0.9* -0.9*
Black 2000-16 -3.2*                     -3.2* -3.2*
Black NHe f 2000-16 -3.3*                     -3.3* -3.3*
APIe 2000-11 -4.0* 2011-14 3.7 2014-16 -12.9             -3.6 -4.9
AI/ANe g 2000-16 -0.4                     -0.4 -0.4
Hispanicf 2000-16 -3.8*                     -3.8* -3.8*

U.S. Cancer Mortalityc, 1975-2016

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16
All Races 1975-84 -4.3* 1984-94 -1.8* 1994-04 -3.4* 2004-16 -0.9*         -0.9* -0.9*
White 1975-84 -4.6* 1984-96 -1.8* 1996-03 -3.6* 2003-16 -0.6*         -0.6* -0.6*
Black 1975-93 -3.0* 1993-04 -4.4* 2004-16 -2.4*             -2.4* -2.4*

U.S. Cancer Mortalityc, 2000-2016

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2007-16 2012-16
All Races 2000-04 -3.6* 2004-16 -0.8*                 -0.8* -0.8*
White 2000-03 -4.2* 2003-16 -0.6*                 -0.6* -0.6*
White NHe f 2000-04 -3.5* 2004-16 -0.5*                 -0.5* -0.5*
Black 2000-16 -2.7*                     -2.7* -2.7*
Black NHe f 2000-16 -2.7*                     -2.7* -2.7*
APIe 2000-16 -3.2*                     -3.2* -3.2*
AI/ANe g 2000-16 -2.8*                     -2.8* -2.8*
Hispanicf 2000-16 -2.3*                     -2.3* -2.3*

Footnotes:

Joinpoint Regression Program Version 4.7, February 2019, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 21 areas (SEER 9 areas, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey, Georgia excluding ATL/RG, Idaho, New York and Massachusetts).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.

g Data for American Indian/Alaska Native are based on the Purchased/Referred Care Delivery Area (PRCDA) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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