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Table 29.2

Age-Adjusted SEER Cancer Incidence Ratesa
By International Classification of Childhood Cancer(ICCC)b Selected Group and Subgroupc and Year of Diagnosis
Excluding benign brain and myelodysplastic syndromes
All Races, Males and Females, Ages 0-19

ICCC Group and Subgroup 1975-2016 1975-1986 1987-1996 1997-2006 2007-2016
All ICCC Groups Combined 162.5 146.3 159.2 165.1 180.2
I Leukemia 39.8 35.4 38.2 41.6 43.8
I(a) Lymphoid leukemia 29.7 26.1 28.7 31.3 32.8
I(b) Acute myeloid leukemia 7.2 6.1 6.9 8.1 7.9
II Lymphomas and reticuloendothelial neoplasms 25.0 24.6 24.4 23.5 27.2
II(a) Hodgkin lymphoma 13.1 14.3 13.4 11.4 13.0
II(b,c,e) Non-Hodgkin lymphoma 11.4 9.6 10.3 11.6 13.9
III CNS & misc intracranial & intraspinal neoplasms 28.6 24.1 29.9 29.4 31.3
III(a) Ependymomas and choroid plexus tumor 2.5 1.9 2.6 2.5 2.9
III(b) Astrocytoma 14.5 12.1 15.7 14.5 16.1
III(c) Intracranial and intraspinal embryonal tumors 5.6 4.5 5.7 6.2 6.0
III(d) Other gliomas 5.2 4.6 5.1 5.6 5.6
IV Neuroblastoma and other peripheral nervous cell tumors 8.6 8.2 8.5 8.7 8.9
IV(a) Neuroblastoma and ganglioneuroblastoma 8.3 8.0 8.2 8.5 8.6
V Retinoblastoma 3.1 2.8 3.2 3.2 3.0
VI Renal tumors 6.7 6.5 6.8 6.6 6.9
VI(a) Nephroblastoma and other nonepithelial renal tumor 6.2 6.2 6.4 6.0 6.2
VII Hepatic tumors 2.0 1.4 1.6 2.3 2.7
VII(a) Hepatoblastoma 1.4 0.9 1.2 1.7 1.9
VIII Malignant bone tumors 8.7 8.4 8.8 8.5 9.3
VIII(a) Osteosarcoma 4.8 4.3 4.9 4.7 5.3
VIII(c) Ewing tumor and related sarcomas of bone 3.0 3.2 2.8 2.8 3.1
IX Soft tissue and other extraosseous sarcomas 11.7 10.7 11.0 12.5 12.6
IX(a) Rhabdomyosarcoma 4.5 4.2 4.8 4.6 4.6
X Germ cell & trophoblastic tumors & neoplasms of gonads 10.7 9.4 10.8 11.0 11.6
X(a) Intracranial and intraspinal germ-cell tumor 1.5 1.0 1.6 1.8 1.8
X(c) Malignant gonadal germ cell tumor 6.8 6.0 6.7 7.0 7.5
XI Other malignant epithelial neoplasms and melanomasd 17.1 14.0 15.2 17.1 22.3
XI(b) Thyroid carcinoma 6.6 5.0 5.2 6.1 10.2
XI(d) Malignant melanoma 5.1 4.2 5.3 5.9 5.1

Footnotes:

a SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta). Rates are per 1,000,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

b International Classification of Childhood Cancer is based on ICD-O-3. Steliarova-Foucher E, Stiller C, Lacour B, Kaatsch P. International Classification of Childhood Cancer, Third Edition. Cancer. April 1, 2005: Vol 103, No. 7 , pg 1457-1467.

c Classifications are shown for invasive cases only except as noted. For ICCC groups and subgroups that include in situ behavior, only invasive cases are shown except as noted.

d Includes in situ urinary bladder tumors.

- Statistic could not be calculated. Rate based on less than 16 cases for the time interval.

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