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Table 8.3

Cancer of the Esophagus (Invasive)

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2017 With up to Five Joinpoints, 2000-2017 With up to Three Joinpoints,

Females by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2017

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17
All Races 1975-97 0.0 1997-17 -1.3*                 -1.3* -1.3*
White 1975-17 -0.2                     -0.2 -0.2
Black 1975-81 8.6* 1981-17 -3.3*                 -3.3* -3.3*

SEER 21 Delay-Adjusted Incidenceb, 2000-2017

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17
All Races 2000-17 -1.6*                     -1.6* -1.6*
White 2000-17 -1.0*                     -1.0* -1.0*
White NHe f 2000-17 -0.8*                     -0.8* -0.8*
Black 2000-17 -4.2*                     -4.2* -4.2*
Black NHe f 2000-17 -4.3*                     -4.3* -4.3*
APIe 2000-17 -2.0*                     -2.0* -2.0*
AI/ANe g 2000-17 -1.1                     -1.1 -1.1
Hispanicf 2000-17 -1.8*                     -1.8* -1.8*

U.S. Cancer Mortalityc, 1975-2017

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17
All Races 1975-00 0.1 2000-17 -1.6*                 -1.6* -1.6*
White 1975-02 0.4* 2002-17 -1.1*                 -1.1* -1.1*
Black 1975-92 -0.2 1992-17 -4.1*                 -4.1* -4.1*

U.S. Cancer Mortalityc, 2000-2017

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17
All Races 2000-17 -1.6*                     -1.6* -1.6*
White 2000-17 -1.0*                     -1.0* -1.0*
White NHe f 2000-17 -0.9*                     -0.9* -0.9*
Black 2000-17 -4.4*                     -4.4* -4.4*
Black NHe f 2000-17 -4.4*                     -4.4* -4.4*
APIe 2000-17 -2.1*                     -2.1* -2.1*
AI/ANe g 2000-17 -0.7                     -0.7 -0.7
Hispanicf 2000-17 -2.3*                     -2.3* -2.3*

Footnotes:

Joinpoint Regression Program Version 4.8, April 2020, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 21 areas (SEER 9 areas, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey, Georgia excluding ATL/RG, Idaho, New York and Massachusetts).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.

g Data for American Indian/Alaska Native are based on the Purchased/Referred Care Delivery Area (PRCDA) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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