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Table 23.2

Cancer of the Prostate (Invasive)

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2017 With up to Five Joinpoints, 2000-2017 With up to Three Joinpoints,

Ages <65 by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2017

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17
All Races 1975-88 3.1* 1988-92 23.4* 1992-01 3.3* 2001-09 0.2 2009-14 -8.2* 2014-17 3.0 -3.7* 0.1
White 1975-88 3.5* 1988-92 23.0* 1992-01 3.1* 2001-09 0.1 2009-14 -8.6* 2014-17 2.1 -4.2* -0.7
Black 1975-89 2.0* 1989-93 26.4* 1993-01 2.7* 2001-10 -0.5 2010-14 -7.5* 2014-17 4.4 -2.1 1.3

SEER 21 Delay-Adjusted Incidenceb, 2000-2017

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17
All Races 2000-10 -0.1 2010-14 -8.7* 2014-17 3.0             -3.1 -0.1
White 2000-09 0.2 2009-14 -8.0* 2014-17 1.9             -3.9* -0.7
White NHe f 2000-09 0.3 2009-14 -7.9* 2014-17 2.7             -3.6 0.0
Black 2000-11 -0.3 2011-14 -8.1 2014-17 2.5             -2.1 -0.3
Black NHe f 2000-11 -0.3 2011-14 -8.1 2014-17 2.7             -2.0 -0.1
APIe 2000-11 0.0 2011-14 -10.1 2014-17 3.7             -2.3 0.0
AI/ANe g 2000-17 -2.9*                     -2.9* -2.9*
Hispanicf 2000-09 -0.3 2009-17 -4.7*                 -4.2* -4.7*

U.S. Cancer Mortalityc, 1975-2017

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17
All Races 1975-87 0.5* 1987-90 3.1 1990-96 -3.2* 1996-00 -5.8* 2000-12 -1.4* 2012-17 -0.1 -0.7 -0.1
White 1975-87 0.7* 1987-90 3.5 1990-02 -4.3* 2002-17 -0.8*         -0.8* -0.8*
Black 1975-92 0.5* 1992-12 -2.9* 2012-17 0.0             -1.3* 0.0

U.S. Cancer Mortalityc, 2000-2017

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17
All Races 2000-17 -1.1*                     -1.1* -1.1*
White 2000-17 -1.0*                     -1.0* -1.0*
White NHe f 2000-17 -1.0*                     -1.0* -1.0*
Black 2000-17 -2.0*                     -2.0* -2.0*
Black NHe f 2000-17 -1.9*                     -1.9* -1.9*
APIe 2000-17 0.2                     0.2 0.2
AI/ANe g 2000-17 -0.1                     -0.1 -0.1
Hispanicf 2000-17 -0.9*                     -0.9* -0.9*

Footnotes:

Joinpoint Regression Program Version 4.8, April 2020, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 21 areas (SEER 9 areas, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey, Georgia excluding ATL/RG, Idaho, New York and Massachusetts).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry.

g Data for American Indian/Alaska Native are based on the Purchased/Referred Care Delivery Area (PRCDA) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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