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Table 28.6

Trends in SEER Incidencea using the Joinpoint Regression Program,

1975-2017 with up to Five Joinpoints by Primary Cancer Site and Age at Diagnosis

Males and Females, All Races (unless otherwise stated)

Ages 0-14

Site Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCb
Years APC Years APC Years APC Years APC Years APC Years APC 2013-17
All Sites, All Races 1975-17 0.6*                     0.6*
All Sites, White 1975-17 0.6*                     0.6*
All Sites, Black 1975-17 0.6*                     0.6*
Bone & Joint 1975-17 0.5*                     0.5*
Brain & Other nervous system 1975-90 2.2* 1990-17 0.2                 0.2
Hodgkin lymphoma 1975-17 -0.5*                     -0.5*
Kidney & Renal pelvis 1975-17 -0.1                     -0.1
Leukemia 1975-17 0.7*                     0.7*
Acute lymphocytic leukemia 1975-17 0.7*                     0.7*
Non-Hodgkin lymphoma 1975-17 1.0*                     1.0*
Soft tissue 1975-17 1.1*                     1.1*

Ages 0-19

Site Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCb
Years APC Years APC Years APC Years APC Years APC Years APC 2013-17
All Sites, All Races 1975-17 0.7*                     0.7*
All Sites, White 1975-17 0.7*                     0.7*
All Sites, Black 1975-17 0.5*                     0.5*
Bone & Joint 1975-17 0.3*                     0.3*
Brain & Other nervous system 1975-89 2.0* 1989-17 0.2                 0.2
Hodgkin lymphoma 1975-17 -0.5*                     -0.5*
Kidney & Renal pelvis 1975-17 0.1                     0.1
Leukemia 1975-17 0.7*                     0.7*
Acute lymphocytic leukemia 1975-17 0.8*                     0.8*
Non-Hodgkin lymphoma 1975-17 1.2*                     1.2*
Soft tissue 1975-17 1.0*                     1.0*

Footnotes:

Joinpoint Regression Program Version 4.8, April 2020, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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