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Table 28.7
Trends in U.S. Mortalitya Using the Joinpoint Regression Program,
1975-2017 With up to Five Joinpoints By Primary Cancer Site, Race and Age at Death
All Races, Ages 0-14
| Site | Joinpoint Trend 1 | Joinpoint Trend 2 | Joinpoint Trend 3 | Joinpoint Trend 4 | Joinpoint Trend 5 | Joinpoint Trend 6 | AAPCb | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | 2013-17 | |
| All Sites | 1975-96 | -2.9* | 1996-17 | -1.3* | -1.3* | ||||||||
| Bone & Joint | 1975-89 | -3.6* | 1989-17 | -0.2 | -0.2 | ||||||||
| Brain & Other nervous system | 1975-99 | -1.2* | 1999-17 | -0.2 | -0.2 | ||||||||
| Hodgkin lymphoma | - | - | - | ||||||||||
| Kidney & Renal pelvis | 1975-17 | -2.6* | -2.6* | ||||||||||
| Leukemia | 1975-90 | -4.4* | 1990-17 | -2.8* | -2.8* | ||||||||
| Acute lymphocytic leukemia | 1975-93 | -5.2* | 1993-17 | -3.1* | -3.1* | ||||||||
| Non-Hodgkin lymphoma | 1975-17 | -4.8* | -4.8* | ||||||||||
| Soft tissue | 1975-79 | 10.4 | 1979-00 | -2.2* | 2000-17 | 1.3* | 1.3* | ||||||
All Races, Ages 0-19
| Site | Joinpoint Trend 1 | Joinpoint Trend 2 | Joinpoint Trend 3 | Joinpoint Trend 4 | Joinpoint Trend 5 | Joinpoint Trend 6 | AAPCb | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | 2013-17 | |
| All Sites | 1975-96 | -2.7* | 1996-17 | -1.4* | -1.4* | ||||||||
| Bone & Joint | 1975-89 | -3.2* | 1989-17 | -0.1 | -0.1 | ||||||||
| Brain & Other nervous system | 1975-07 | -1.1* | 2007-17 | 0.4 | 0.4 | ||||||||
| Hodgkin lymphoma | 1975-17 | -5.2* | -5.2* | ||||||||||
| Kidney & Renal pelvis | 1975-17 | -2.4* | -2.4* | ||||||||||
| Leukemia | 1975-88 | -3.9* | 1988-17 | -2.8* | -2.8* | ||||||||
| Acute lymphocytic leukemia | 1975-93 | -4.5* | 1993-17 | -3.0* | -3.0* | ||||||||
| Non-Hodgkin lymphoma | 1975-17 | -4.1* | -4.1* | ||||||||||
| Soft tissue | 1975-79 | 9.9* | 1979-01 | -1.3* | 2001-17 | 0.6 | 0.6 | ||||||
White, Ages 0-14
| Site | Joinpoint Trend 1 | Joinpoint Trend 2 | Joinpoint Trend 3 | Joinpoint Trend 4 | Joinpoint Trend 5 | Joinpoint Trend 6 | AAPCb | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | 2013-17 | |
| All Sites | 1975-96 | -3.0* | 1996-17 | -1.2* | -1.2* | ||||||||
| Bone & Joint | 1975-91 | -3.0* | 1991-17 | -0.1 | -0.1 | ||||||||
| Brain & Other nervous system | 1975-17 | -0.8* | -0.8* | ||||||||||
| Hodgkin lymphoma | - | - | - | ||||||||||
| Kidney & Renal pelvis | 1975-17 | -2.7* | -2.7* | ||||||||||
| Leukemia | 1975-90 | -4.5* | 1990-17 | -2.8* | -2.8* | ||||||||
| Acute lymphocytic leukemia | 1975-90 | -5.6* | 1990-17 | -3.1* | -3.1* | ||||||||
| Non-Hodgkin lymphoma | 1975-17 | -4.9* | -4.9* | ||||||||||
| Soft tissue | 1975-79 | 13.0* | 1979-95 | -2.9* | 1995-17 | 0.9* | 0.9* | ||||||
White, Ages 0-19
| Site | Joinpoint Trend 1 | Joinpoint Trend 2 | Joinpoint Trend 3 | Joinpoint Trend 4 | Joinpoint Trend 5 | Joinpoint Trend 6 | AAPCb | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | 2013-17 | |
| All Sites | 1975-96 | -2.7* | 1996-17 | -1.3* | -1.3* | ||||||||
| Bone & Joint | 1975-89 | -2.8* | 1989-17 | -0.1 | -0.1 | ||||||||
| Brain & Other nervous system | 1975-17 | -0.8* | -0.8* | ||||||||||
| Hodgkin lymphoma | 1975-17 | -5.2* | -5.2* | ||||||||||
| Kidney & Renal pelvis | 1975-17 | -2.5* | -2.5* | ||||||||||
| Leukemia | 1975-88 | -4.1* | 1988-17 | -2.7* | -2.7* | ||||||||
| Acute lymphocytic leukemia | 1975-82 | -3.3* | 1982-88 | -6.4* | 1988-17 | -2.9* | -2.9* | ||||||
| Non-Hodgkin lymphoma | 1975-17 | -4.3* | -4.3* | ||||||||||
| Soft tissue | 1975-79 | 11.7* | 1979-96 | -1.7* | 1996-17 | 0.4 | 0.4 | ||||||
Black, Ages 0-14
| Site | Joinpoint Trend 1 | Joinpoint Trend 2 | Joinpoint Trend 3 | Joinpoint Trend 4 | Joinpoint Trend 5 | Joinpoint Trend 6 | AAPCb | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | 2013-17 | |
| All Sites | 1975-97 | -2.6* | 1997-17 | -1.2* | -1.2* | ||||||||
| Bone & Joint | 1975-81 | -10.1* | 1981-17 | -0.7 | -0.7 | ||||||||
| Brain & Other nervous system | 1975-09 | -1.2* | 2009-17 | 2.7 | 2.7 | ||||||||
| Hodgkin lymphoma | - | - | - | ||||||||||
| Kidney & Renal pelvis | 1975-17 | -2.5* | -2.5* | ||||||||||
| Leukemia | 1975-17 | -3.1* | -3.1* | ||||||||||
| Acute lymphocytic leukemia | 1975-85 | -1.1 | 1985-93 | -8.9* | 1993-17 | -3.0* | -3.0* | ||||||
| Non-Hodgkin lymphoma | 1975-91 | -6.7* | 1991-17 | -1.7 | -1.7 | ||||||||
| Soft tissue | 1975-17 | -0.8* | -0.8* | ||||||||||
Black, Ages 0-19
| Site | Joinpoint Trend 1 | Joinpoint Trend 2 | Joinpoint Trend 3 | Joinpoint Trend 4 | Joinpoint Trend 5 | Joinpoint Trend 6 | AAPCb | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | Years | APC | 2013-17 | |
| All Sites | 1975-10 | -2.1* | 2010-17 | -0.1 | -0.1 | ||||||||
| Bone & Joint | 1975-84 | -6.7* | 1984-17 | -0.3 | -0.3 | ||||||||
| Brain & Other nervous system | 1975-08 | -1.2* | 2008-17 | 2.0 | 2.0 | ||||||||
| Hodgkin lymphoma | - | - | - | ||||||||||
| Kidney & Renal pelvis | 1975-17 | -2.1* | -2.1* | ||||||||||
| Leukemia | 1975-17 | -2.9* | -2.9* | ||||||||||
| Acute lymphocytic leukemia | 1975-17 | -3.9* | -3.9* | ||||||||||
| Non-Hodgkin lymphoma | 1975-17 | -3.2* | -3.2* | ||||||||||
| Soft tissue | 1975-17 | -0.7* | -0.7* | ||||||||||
Footnotes:
Joinpoint Regression Program Version 4.8, April 2020, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).
The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).
a Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.
b The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint over the time range of 1975-2017.
* The APC/AAPC is significantly different from zero (p<.05).
- Joinpoint regression line analysis could not be performed on data series.
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