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Table 1.8

SEER Incidence and U.S. Mortality Trends (APC) by Primary Cancer Site and Sex
Whites, 2009-2018

Site Incidencea US Mortalityb
Both Sexes Males Females Both Sexes Males Females
All Sites -1.0* -1.6* -0.3* -1.5* -1.8* -1.4*
Oral Cavity & Pharynx: 0.6* 0.7* 0.3* 0.9* 1.0* 0.3
Lip -1.9 -2.5* -0.6 -0.9 -3.0 3.2
Tongue 1.8* 1.7* 1.9* 1.9* 2.2* 1.4*
Salivary gland -0.1 -0.4 0.2 1.0* 0.6 1.5
Floor of mouth -3.5* -3.4* -3.8* -3.1* -3.0 -3.5
Gum & other oral cavity -0.2 -0.2 -0.2 0.5 0.7 0.3
Nasopharynx -2.1* -2.0* -2.4* -1.3* -0.9 -2.1
Tonsil 1.9* 2.2* 0.6 2.6* 3.2* 0.2
Oropharynx 5.1* 5.5* 3.6* 3.9* 4.4* 2.1*
Hypopharynx -2.9* -2.8* -3.5* 1.5 1.4 1.0
Other oral cavity & pharynx 0.1 0.5 -1.1 -2.5* -2.5* -2.9*
Digestive System: -0.7* -0.9* -0.6* -0.4* -0.5* -0.5*
Esophagus -0.9* -1.1* -0.9 -0.8* -0.9* -1.1*
Stomach -0.9* -1.6* 0.1 -2.0* -2.3* -1.8*
Small intestine 0.9* 0.8 1.0* 2.1* 2.6* 1.3
Colon & Rectum: -1.8* -2.0* -1.7* -1.8* -2.0* -1.8*
Colon -2.0* -2.3* -1.9* - - -
Rectum -1.4* -1.5* -1.4* - - -
Anus, anal canal & anorectum 1.1* 0.6 1.5* 3.1* 2.9* 3.3*
Liver & intrahepatic bile duct 1.6* 1.1* 2.5* 1.9* 1.6* 2.2*
Gallbladder -0.9* -0.6 -0.9* -1.7* -2.0* -1.4*
Other biliary -0.8 -0.8 -0.9 1.0* 0.9 1.0*
Pancreas 0.7* 0.7* 0.6* 0.3* 0.3* 0.2*
Retroperitoneum -0.3 0.0 -0.7 3.4* 3.8* 2.8
Peritoneum, omentum & mesentery -4.0* -3.0 -4.0* 0.7 2.9* 0.3
Other digestive system 5.3* 5.0* 5.5* 3.6* 2.7* 4.3*
Respiratory System: -2.2* -2.9* -1.4* -3.4* -3.9* -2.8*
Nose, nasal cavity & middle ear -0.3 -0.7 0.1 -0.2 -0.1 -0.7
Larynx -2.9* -3.2* -2.6* -1.8* -1.9* -2.0*
Lung & bronchus -2.2* -3.0* -1.4* -3.4* -4.1* -2.8*
Pleura -4.4 -5.7 -3.7 4.6* 4.3* 4.2*
Trachea & other respiratory organs -0.7 -0.6 -1.1 1.7 0.8 2.7*
Bones & joints 0.3 0.4 0.1 1.6* 1.6* 1.4*
Soft tissue (including heart) 0.0 0.1 -0.3 0.1 -0.1 0.1
Skin (excl. basal & squamous): 1.1* 0.9* 1.1* -1.8* -1.9* -1.9*
Melanoma of the skin 1.1* 1.0* 1.2* -3.3* -3.5* -3.2*
Other non-epithelial skin 0.4 0.7 -0.2 2.4* 2.0* 2.7*
Breast -0.1 0.4 0.1 -1.5* -0.6 -1.4*
Breast (in situ) -1.9* 1.3 -1.8* - - -
Female Genital System: -0.2 - 0.0 -0.7* - -0.4*
Cervix uteri -0.4 - -0.3 0.0 - 0.2
Corpus uteri 0.5* - 0.6* 5.0* - 5.3*
Uterus, NOS 2.2* - 2.6* -1.4 - -1.1
Ovaryc -2.8* - -2.6* -2.6* - -2.4*
Vagina -1.8* - -1.6* -2.7* - -2.5*
Vulva 0.3 - 0.6 2.0* - 2.4*
Other female genital system 9.1* - 9.1* 6.7* - 6.9*
Male Genital System: -3.3* -3.5* - -0.8* -1.4* -
Prostate -3.6* -3.8* - -0.8* -1.5* -
Testis 0.5* 0.5* - -0.1 -0.2 -
Penis 0.0 -0.1 - 3.4* 3.2* -
Other male genital system -1.2 -1.7 - 1.6 0.9 -
Urinary System: -0.6* -0.9* -0.4 -0.7* -0.8* -0.9*
Urinary bladder -1.5* -1.7* -1.5* -0.4 -0.6* -0.4
Kidney & renal pelvis 0.6* 0.5* 0.6* -1.2* -1.2* -1.4*
Ureter -1.6* -1.7* -1.7 0.0 0.2 -0.3
Other urinary system 3.8* 2.7* 5.4* 0.2 0.6 -1.1
Eye & Orbit -0.6 -1.0 -0.3 0.8 1.2 0.3
Brain & Nervous System:d -0.5* -0.5* -0.6 0.5* 0.4* 0.5
Brain -0.4 -0.5* -0.4 - - -
Cranial nerves & other nervous system -2.1* -1.3 -2.9* - - -
Endocrine System: -0.1 0.6 -0.3 -0.1 0.2 -0.2
Thyroid -0.1 0.6 -0.3 0.2 0.5 0.0
Other endocrine & thymus -0.2 0.3 -0.9 -0.4 -0.3 -0.6
Lymphoma: -0.9* -0.9* -0.9* -2.3* -2.0* -2.7*
Hodgkin lymphoma -1.5* -1.5* -1.5* -4.4* -4.0* -5.0*
Non-Hodgkin lymphoma -0.8* -0.8* -0.8* -2.2* -1.9* -2.6*
Myeloma 0.2 0.0 0.2 -0.8* -0.8* -1.0*
Leukemia: -0.7 -0.8 -0.7 -1.7* -1.8* -1.7*
Lymphocytic: -1.3* -1.4* -1.3* -2.1* -2.2* -2.2*
Acute lymphocytic 0.2 0.5 -0.1 -0.1 0.4 -1.0
Chronic lymphocytic -1.8* -2.0* -1.8* -3.0* -3.1* -2.9*
Other lymphocytic -0.9 -1.0 -0.9 -0.5 -1.1 0.4
Myeloid & Monocytic: 0.1 -0.1 0.2 -0.1 -0.2 -0.1
Acute myeloid 0.4 0.2 0.6 -0.4* -0.5* -0.3
Chronic myeloid 0.1 0.0 0.1 0.1 -0.1 0.2
Acute monocytic -4.0* -4.2* -3.8* -2.1 -1.8 -2.6
Other myeloid & monocytic -3.8* -3.3* -4.8* 2.4* 2.6* 1.9*
Other leukemia: -1.4 -0.8 -2.0 -4.8* -4.9* -4.9*
Other acute leukemia -3.5* -3.0* -3.9* -6.4* -6.4* -6.8*
Aleukemic, subleukemic & NOS -0.4 0.2 -1.1 -3.9* -4.2* -3.8*
Kaposi Sarcomae -5.1* -5.2* -6.5* - - -
Mesotheliomae -3.3* -4.5* 0.1 - - -
Ill-defined & unspecified -2.1* -2.3* -1.9* -1.3* -1.5* -1.1*

Footnotes:

The APC is the Annual Percent Change over the time interval. Trends are based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a SEER 21 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey, Georgia excluding ATL/RG, Idaho, New York and Massachusetts).

b US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

c Ovary excludes borderline cases or histologies 8442, 8451, 8462, 8472, and 8473.

d Due to coding changes, Brain & Nervous System mortality are no longer shown separately.

e Trend not shown for mortality. Category did not exist in mortality coding until 1999.

* The APC is significantly different from zero (p<.05).

- Statistic could not be calculated. Trend based on less than 10 cases for at least one year within the time interval.

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