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Table 3.9

Age-Adjusted SEER Incidencea , by Year and Sex

By Adapted Classification Scheme for Tumors of Adolescents and Young Adultsb

All Races, Ages 25-29

Both Sexes

Site 1975-2018 2009-2018
Count Rate AAPCc Count Rate AAPCc
All Sites Combined 50,538 57.2 0.5 13,778 64.4 -0.6
1. Leukemias 2,174 2.5 0.8* 594 2.8 0.8*
2. Lymphomas 7,312 8.3 0.2 1,743 8.1 -1.7*
3. CNS, intracranial, intraspinal 2,553 2.9 -0.1 640 3.0 -4.2
4. Osseous & chondromatous neoplasms 632 0.7 1.2* 189 0.9 1.2*
5. Soft tissue sarcomas 3,456 3.9 1.1 615 2.9 -0.6
6. Germ cell and trophoblastic neoplasms 6,427 7.3 0.9* 1,790 8.4 -0.9
7. Melanoma and skin carcinomas 6,713 7.6 0.3 1,663 7.8 -2.8*
8. Carcinomas (excluding skin) 20,233 22.9 0.7* 6,129 28.6 1.6*
9. Miscellaneous specified neoplasms, NOS 782 0.9 3.1* 345 1.6 1.9
10. Unspecified malignant neoplasms 235 0.3 - 57 0.3 -

Males

Site 1975-2018 2009-2018
Count Rate AAPCc Count Rate AAPCc
All Sites Combined 22,577 50.8 0.5 5,889 54.2 -1.2*
1. Leukemias 1,248 2.8 0.5* 331 3.0 0.5*
2. Lymphomas 4,173 9.4 0.5 998 9.2 0.1
3. CNS, intracranial, intraspinal 1,391 3.1 0.6* 356 3.3 0.6*
4. Osseous & chondromatous neoplasms 350 0.8 0.2 95 0.9 0.2
5. Soft tissue sarcomas 2,506 5.6 1.3 397 3.7 -0.7
6. Germ cell and trophoblastic neoplasms 5,932 13.3 1.1 1,662 15.3 -0.6
7. Melanoma and skin carcinomas 2,355 5.3 -1.3 534 4.9 -6.5
8. Carcinomas (excluding skin) 4,211 9.5 0.6 1,355 12.5 2.0*
9. Miscellaneous specified neoplasms, NOS 301 0.7 - 132 1.2 -
10. Unspecified malignant neoplasms 98 0.2 - 22 0.2 -

Females

Site 1975-2018 2009-2018
Count Rate AAPCc Count Rate AAPCc
All Sites Combined 27,961 63.8 0.7* 7,889 75.0 1.1*
1. Leukemias 926 2.1 1.2* 263 2.5 1.2*
2. Lymphomas 3,139 7.2 0.5 745 7.1 -0.6
3. CNS, intracranial, intraspinal 1,162 2.7 0.6* 284 2.7 0.6*
4. Osseous & chondromatous neoplasms 282 0.6 1.9* 94 0.9 1.9*
5. Soft tissue sarcomas 950 2.2 0.4 218 2.1 -1.3*
6. Germ cell and trophoblastic neoplasms 495 1.1 -0.1 128 1.2 -0.1
7. Melanoma and skin carcinomas 4,358 9.9 0.7* 1,129 10.7 -2.9*
8. Carcinomas (excluding skin) 16,022 36.5 0.8* 4,774 45.4 1.7*
9. Miscellaneous specified neoplasms, NOS 481 1.1 4.0* 213 2.0 4.0*
10. Unspecified malignant neoplasms 137 0.3 - 35 0.3 -

Footnotes:

Rates are per 100,000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Rates are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta).

b Adapted from: RD Barr, EJ Holowaty, JM Birch. Classification Scheme for tumors diagnosed in adolescents and young adults. Cancer. 106:7; 1425-1430. (Restricted to malignant tumors and updated based on ICD-O-3 definitions).

c The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint over the time range of 1975-2018.

- Statistic could not be calculated. Count and rate based on less than 16 cases for the time interval. AAPC could not be calculated due to insufficient data.

* The AAPC is significantly different from zero (p<.05).

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