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Table 3.17

SEER Incidencea and U.S. Mortalityb Rates and Trends for the Top 5 Cancer Sitesc by Age

All Races, Both Sexes, 1975-2018

Ages 15-19

Site Incidence Mortality
1975-2018 2009-2018 1975-2018 2009-2018
Rate AAPCd Rate AAPCd Rate AAPCd Rate AAPCd
All Malignant Cancers 21.3 0.8* 24.4 0.8* 3.9 -1.7* 2.9 -0.5
Hodgkin Lymphoma 3.4 -0.5* 3.3 -0.5* 0.2 -5.1* 0.0 -5.9*
Brain and Other Nervous System 2.1 0.5* 2.3 0.5* 0.6 -0.9* 0.5 -0.9*
Thyroid 2.1 2.2* 3.4 2.8 0.0 - - -
Non-Hodgkin Lymphoma 1.7 1.5* 2.1 1.5* 0.3 -3.5* 0.1 -4.8*
Testis 1.6 0.2 1.7 -4.4 0.1 -4.9* 0.0 -2.4*

Ages 20-24

Site Incidence Mortality
1975-2018 2009-2018 1975-2018 2009-2018
Rate AAPCd Rate AAPCd Rate AAPCd Rate AAPCd
All Malignant Cancers 35.2 0.7* 39.1 -0.1 5.3 -1.7* 4.1 -2.9*
Hodgkin Lymphoma 4.9 0.1 4.5 -0.7* 0.4 -5.4* 0.1 -11.5*
Thyroid 4.7 1.6* 6.8 0.6 0.0 - 0.0 -
Testis 4.6 1.0* 5.4 1.0* 0.2 -3.4* 0.2 -0.6
Melanoma of the Skin 4.1 0.1 4.0 -3.3* 0.2 -4.9* 0.1 -12.4*
Brain and Other Nervous System 2.3 0.2 2.3 -2.3 0.6 -0.7* 0.6 -0.7*

Ages 25-29

Site Incidence Mortality
1975-2018 2009-2018 1975-2018 2009-2018
Rate AAPCd Rate AAPCd Rate AAPCd Rate AAPCd
All Malignant Cancers 57.2 0.5 64.4 -0.6 8.0 -1.5* 6.2 -1.5*
Thyroid 7.7 1.6* 11.7 0.5 0.0 - 0.0 -
Melanoma of the Skin 7.4 0.1 7.6 -4.0* 0.5 -3.0* 0.3 -3.0*
Testis 6.5 0.7* 7.6 -1.2 0.3 -2.8* 0.2 0.8
Hodgkin Lymphoma 4.8 -0.2 4.3 -0.2 0.5 -5.6* 0.2 -10.8*
Breast 4.3 0.5 4.9 1.9* 0.5 -1.6* 0.4 0.2

Ages 30-34

Site Incidence Mortality
1975-2018 2009-2018 1975-2018 2009-2018
Rate AAPCd Rate AAPCd Rate AAPCd Rate AAPCd
All Malignant Cancers 88.3 0.8* 99.9 0.2 13.9 -1.3* 10.9 -0.3
Breast 13.6 0.2 14.4 0.7* 2.0 -1.5* 1.4 0.5
Melanoma of the Skin 10.8 1.4* 12.1 0.2 0.8 -2.4* 0.5 -2.7*
Thyroid 10.2 2.4* 16.9 1.1 0.0 -1.2* 0.0 -1.2*
Testis 6.7 1.8* 7.9 0.7* 0.3 -2.1* 0.2 1.8*
Cervix Uteri 5.6 -1.1* 4.7 -1.1* 0.8 -0.7* 0.7 1.9*

Ages 35-39

Site Incidence Mortality
1975-2018 2009-2018 1975-2018 2009-2018
Rate AAPCd Rate AAPCd Rate AAPCd Rate AAPCd
All Malignant Cancers 135.7 0.7* 145.1 0.1 25.9 -1.4* 19.5 -0.5*
Breast 31.8 0.4* 32.3 0.3* 4.8 -1.4* 3.3 -0.4
Melanoma of the Skin 14.2 1.3* 15.1 0.3* 1.2 -2.7* 0.7 -3.7*
Thyroid 12.3 2.5* 20.4 0.0 0.1 -0.5 0.1 -0.5
Non-Hodgkin Lymphoma 7.8 1.1 7.1 -3.6* 1.4 -1.8* 0.7 -3.1*
Colon and Rectum 7.7 1.3* 10.2 2.7* 2.1 -0.3* 2.3 1.2*

Footnotes:

Rates are per 100,000.

a SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta).

b US Mortality Files, National Center for Health Statistics, CDC.

c Top 5 cancer sites selected based on 1975-2018 SEER 9 Incidence rates for the age group.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint over the time range of 1975-2018.

- Statistic could not be calculated. Count and rate based on less than 16 cases for the time interval. AAPC could not be calculated due to insufficient data.

* The AAPC is significantly different from zero (p<.05).

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