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Table 2.1

All Cancer Sites (Invasive)

Trends in SEER Incidencea b and U.S. Mortalityc Using the Joinpoint Regression Program,

1975-2015 With up to Five Joinpoints, 1992-2015 With up to Four Joinpoints,

Both Sexes by Race/Ethnicity

SEER 9 Delay-Adjusted Incidencea, 1975-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1975-89 1.2* 1989-92 2.8 1992-95 -2.4 1995-98 1.1 1998-09 -0.3* 2009-15 -1.2* -0.9* -1.2*
White 1975-82 0.8* 1982-92 1.8* 1992-95 -2.1 1995-98 1.3 1998-08 -0.2 2008-15 -1.0* -0.8* -1.0*
Black 1975-84 1.6* 1984-89 0.4 1989-92 4.8* 1992-95 -1.7 1995-09 -0.4* 2009-15 -1.9* -1.4* -1.9*

SEER 13 Delay-Adjusted Incidenceb, 1992-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1992-94 -3.1* 1994-99 0.4 1999-05 -0.7* 2005-08 0.4 2008-15 -1.4*     -1.0* -1.4*
White 1992-94 -3.3* 1994-98 0.6 1998-09 -0.3* 2009-13 -1.8* 2013-15 0.3     -0.8* -0.8
Black 1992-09 -0.5* 2009-15 -2.0*                 -1.5* -2.0*

SEER 9 Observed Incidencea, 1975-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1975-89 1.2* 1989-92 2.8 1992-95 -2.4 1995-98 1.1 1998-09 -0.3* 2009-15 -1.5* -1.1* -1.5*
White 1975-82 0.8* 1982-92 1.8* 1992-95 -2.1 1995-98 1.3 1998-08 -0.2 2008-15 -1.3* -1.1* -1.3*
Black 1975-84 1.6* 1984-89 0.4 1989-92 4.8* 1992-95 -1.6 1995-09 -0.5* 2009-15 -2.4* -1.8* -2.4*

SEER 13 Observed Incidenceb, 1992-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1992-94 -3.1* 1994-99 0.4 1999-05 -0.7* 2005-08 0.3 2008-15 -1.7*     -1.2* -1.7*
White 1992-94 -3.1* 1994-01 0.4 2001-04 -1.2 2004-08 0.3 2008-15 -1.6*     -1.2* -1.6*
White NHe f 1992-94 -2.9* 1994-01 0.5* 2001-04 -1.4 2004-07 0.9 2007-15 -1.4*     -1.1* -1.4*
Black 1992-09 -0.6* 2009-15 -2.6*                 -1.9* -2.6*
Black NHe f 1992-09 -0.5* 2009-15 -2.5*                 -1.8* -2.5*
APIe 1992-09 -0.4* 2009-15 -1.6*                 -1.2* -1.6*
AI/ANe g 1992-15 0.0                     0.0 0.0
Hispanicf 1992-94 -3.5 1994-02 0.4 2002-11 -0.4* 2011-15 -2.2*         -1.2* -2.2*

U.S. Cancer Mortalityc, 1975-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1975-84 0.5* 1984-91 0.3* 1991-94 -0.5 1994-98 -1.3* 1998-01 -0.8* 2001-15 -1.5* -1.5* -1.5*
White 1975-90 0.4* 1990-94 -0.3 1994-98 -1.2* 1998-01 -0.6 2001-15 -1.4*     -1.4* -1.4*
Black 1975-83 1.3* 1983-91 0.7* 1991-95 -0.8* 1995-01 -1.6* 2001-15 -2.1*     -2.1* -2.1*

U.S. Cancer Mortalityc, 1992-2015

Race/Ethnicity Joinpoint Trend 1 Joinpoint Trend 2 Joinpoint Trend 3 Joinpoint Trend 4 Joinpoint Trend 5 Joinpoint Trend 6 AAPCd
Years APC Years APC Years APC Years APC Years APC Years APC 2006-15 2011-15
All Races 1992-01 -1.0* 2001-15 -1.5*                 -1.5* -1.5*
White 1992-94 -0.3 1994-98 -1.2* 1998-01 -0.6 2001-15 -1.4*         -1.4* -1.4*
White NHe f 1992-94 0.2 1994-98 -1.2* 1998-01 -0.5 2001-15 -1.4*         -1.4* -1.4*
Black 1992-99 -1.3* 1999-15 -2.1*                 -2.1* -2.1*
Black NHe f 1992-94 0.0 1994-01 -1.6* 2001-15 -2.0*             -2.0* -2.0*
APIe 1992-15 -1.3*                     -1.3* -1.3*
AI/ANe g 1992-04 0.4 2004-15 -1.1*                 -1.1* -1.1*
Hispanicf 1992-98 0.2 1998-15 -1.2*                 -1.2* -1.2*

Footnotes:

Joinpoint Regression Program Version 4.6, February 2018, National Cancer Institute. (https://surveillance.cancer.gov/joinpoint/).

The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130).

a Trends are from the SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, and Atlanta).

b Trends are from the SEER 13 areas (SEER 9 Areas, Los Angeles, San Jose-Monterey, Rural Georgia, and the Alaska Native Registry).

c Trends are from US Mortality Files, National Center for Health Statistics, Centers for Disease Control and Prevention.

d The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpoint.

e API - Asian/Pacific Islander, AI/AN - American Indian/Alaska Native, NH - Non-Hispanic

f Hispanic and Non-Hispanic are not mutually exclusive from whites, blacks, Asian/Pacific Islanders, and American Indians/Alaska Natives. Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registry. The Hispanic and Non-Hispanic mortality trends exclude deaths from New Hampshire and Oklahoma.

g Data for American Indian/Alaska Native are based on the CHSDA(Contract Health Service Delivery Area) counties.

* The APC/AAPC is significantly different from zero (p<.05).

- Joinpoint regression line analysis could not be performed on data series.

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