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Table 15.13

Small Cell Cancer of the Lung and Bronchus (Invasive)

5-Year Relative Survival (Percent) by Year of Diagnosis

Year of
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
1975-1977a 3.6 3.1 4.8 3.7 3.1 4.9 3.7 3.8 3.6
1978-1980a 4.2 3.2 6.5 4.3 3.3 6.4 3.1 2.4 5.0
1981-1983a 4.5 3.5 6.2 4.6 3.6 6.1 5.3 4.1 8.2
1984-1986a 4.5 3.5 6.2 4.7 3.6 6.4 3.5 2.2 5.6
1987-1989a 5.0 3.9 6.6 5.1 3.8 6.8 4.0 3.3 5.1
1990-1992a 5.4 4.5 6.4 5.4 4.5 6.5 4.2 3.9 4.4
1993-1995a 6.4 5.1 7.8 6.2 5.0 7.6 6.7 4.0 10.4
1996-1998a 5.8 5.3 6.5 6.0 5.5 6.6 3.6 2.6 4.5
1999-2001a 5.7 4.8 6.7 5.6 4.4 6.9 5.2 6.0 4.2
2002-2004a 6.5 4.7 8.2 6.5 4.4 8.5 5.3 5.3 5.1
2005-2009a 6.8 5.2 8.5 6.7 5.1 8.4 6.7 4.5 8.9
2010-2016a 7.0e 5.7e 8.2e 7.0e 5.7e 8.2e 7.5e 7.1e 7.8

5-Year Period Survival (Percent)cd

Year All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
2016 6.7 5.0 8.4 6.7 4.9 8.4 7.7 7.0 8.5

Stage Distribution (%) 2010-2016ce, Case Counts and Percentages

Stage at
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
Number of cases 33,251 16,684 16,567 28,703 14,145 14,558 3,033 1,549 1,484
Percent 100% 100% 100% 100% 100% 100% 100% 100% 100%
Localized 4 4 4 4 3 4 4 4 4
Regional 20 18 22 20 18 22 19 17 21
Distant 75 77 72 75 77 72 75 77 74
Unstaged/Unknown 2 2 2 2 2 2 2 2 1

5-Year Relative Survival (Percent) 2010-2016c by Age at Diagnosis

Age at
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
Ages <45 13.3 9.6 17.2 14.0 10.9 17.3 10.6 - -
Ages 45-54 9.7 7.0 12.1 9.4 6.4 12.0 12.1 11.6 12.8
Ages 55-64 7.8 5.7 10.0 7.8 5.6 10.0 8.0 5.9 10.1
Ages 65-74 6.2 5.5 7.0 6.2 5.3 7.1 7.1 7.9 6.2
Ages 75+ 3.7 2.8 4.5 3.7 2.7 4.5 3.5 2.1 4.5
Ages <65 8.4 6.1 10.7 8.3 5.9 10.7 9.2 7.5 10.9
Ages 65+ 5.2 4.5 6.0 5.2 4.3 6.0 5.8 6.1 5.5

5-Year Relative Survival (Percent) 2010-2016c by Stage at Diagnosise

Stage at
Diagnosis
All Races Whites Blacks
Both Sexes Males Females Both Sexes Males Females Both Sexes Males Females
All Stages 6.5 5.1 7.9 6.5 5.0 7.9 7.5 6.8 8.2
Localized 27.2 25.5 28.3 27.2 25.4 28.4 34.9f 37.4f 32.1f
Regional 16.4 14.8 17.7 16.5 14.7 18.0 17.5 16.1 18.7
Distant 2.9 2.0 3.8 2.8 1.9 3.7 3.8 3.3 4.2
Unstaged/Unknown 8.1 5.7 10.2 8.0 4.2 11.0 3.4 6.6f -

Footnotes:

Note: Small Cell Cancer of the Lung and Bronchus includes histologies 8002, 8041-8045.

a SEER 9 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta). Based on follow-up of patients into 2017. Expected survival rates are derived from the U.S. Annual Life Tables.

b SEER 18 areas (San Francisco, Connecticut, Detroit, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, San Jose-Monterey, Los Angeles, Alaska Native Registry, Rural Georgia, California excluding SF/SJM/LA, Kentucky, Louisiana, New Jersey and Georgia excluding ATL/RG). Expected survival rates are derived from life tables by socio-economic status, geography and race developed by the SEER program. Based on follow-up of patients into 2017.

c Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimates from several cohorts. It is computed here using three year calendar blocks (2010-2012: 0-1 year survival), (2009-2011: 1-2 year survival), (2008-2010: 2-3 year survival), (2007-2009: 3-4 year survival), (2006-2008: 4-5 years survival).

d Stage at diagnosis is classified using SEER Summary Stage 2000. Stage distribution percentages may not sum to 100 due to rounding.

e The difference between 1975-1977 and 2010-2016 is statistically significant (p<.05).

f The standard error is between 5 and 10 percentage points.

g The standard error is greater than 10 percentage points.

- Statistic could not be calculated due to fewer than 25 cases during the time period.

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