Main Classification Table from the ICCC-3 based on ICD-O-31

The table below provides the definition for this International Classification of Childhood Cancer, Third edition (ICCC-3) variable. To see other variable definitions, see the ICCC home page.

Caution: The ICCC recode in the SEER databases through the November 2011 submission incorrectly classifies some benign and borderline tumors into specific groups. Benign and borderline tumors should only be in III (all sub categories) and X(a). Please group all other benign and borderline tumors with non-classifiable. This problem was fixed starting with the November 2012 submission.

Site Group ICD-O-3 Histology (Type) ICD-O-2/3 Site Recode
I Leukemias, myeloproliferative diseases, and myelodysplastic diseases      
(a) Lymphoid leukemias 9820, 9823, 9826, 9827, 9831-9837, 9940, 9948 C000-C809 011
(b) Acute myeloid leukemias 9840, 9861, 9866, 9867, 9870-9874, 9891, 9895-9897, 9910, 9920, 9931 C000-C809 012
(c) Chronic myeloproliferative diseases 9863, 9875, 9876, 9950, 9960-9964 C000-C809 013
(d) Myelodysplastic syndrome and other myeloproliferative diseases 9945, 9946, 9975, 9980, 9982-9987, 9989 C000-C809 014
(e) Unspecified and other specified leukemias 9800, 9801, 9805, 9860, 9930 C000-C809 015
II Lymphomas and reticuloendothelial neoplasms      
(a) Hodgkin lymphomas 9650-9655, 9659, 9661-9665, 9667 C000-C809 021
(b) Non-Hodgkin lymphomas (except Burkitt lymphoma) 9591, 9670, 9671, 9673, 9675, 9678-9680, 9684, 9689-9691, 9695, 9698-9702, 9705, 9708, 9709, 9714, 9716-9719, 9727-9729, 9731-9734, 9760-9762, 9764-9769, 9970 C000-C809 022
(c) Burkitt lymphoma 9687 C000-C809 023
(d) Miscellaneous lymphoreticular neoplasms 9740-9742, 9750, 9754-9758 C000-C809 024
(e) Unspecified lymphomas 9590, 9596 C000-C809 025
III CNS and miscellaneous intracranial and intraspinal neoplasms      
(a) Ependymomas and choroid plexus tumor 9383, 9390-9394 C000-C809 031
(b) Astrocytomas 9380 C723 032
9384, 9400-9411, 9420, 9421-9424, 9440-9442 C000-C809 032
(c) Intracranial and intraspinal embryonal tumors 9470-9474, 9480, 9508 C000-C809 033
9501-9504 C700-C729 033
(d) Other gliomas 9380 C700-C722, C724-C729, C751, C753 034
9381, 9382, 9430, 9444, 9450, 9451, 9460 C000-C809 034
(e) Other specified intracranial and intraspinal neoplasms 8270-8281, 8300, 9350-9352, 9360-9362, 9412, 9413, 9492, 9493, 9505-9507, 9530-9539, 9582 C000-C809 035
(f) Unspecified intracranial and intraspinal neoplasms 8000-8005 C700-C729, C751-C753 036
IV Neuroblastoma and other peripheral nervous cell tumors      
(a) Neuroblastoma and ganglioneuroblastoma 9490, 9500 C000-C809 041
(b) Other peripheral nervous cell tumors 8680-8683, 8690-8693, 8700, 9520-9523 C000-C809 042
9501-9504 C000-C699, C739-C768, C809 042
V Retinoblastoma 9510-9514 C000-C809 050
VI Renal tumors      
(a) Nephroblastoma and other nonepithelial renal tumors 8959, 8960, 8964-8967 C000-C809 061
8963, 9364 C649 061
(b) Renal carcinomas 8010-8041, 8050-8075, 8082, 8120-8122, 8130-8141, 8143, 8155, 8190-8201, 8210, 8211, 8221-8231, 8240, 8241, 8244-8246, 8260-8263, 8290, 8310, 8320, 8323, 8401, 8430, 8440, 8480-8490, 8504, 8510, 8550, 8560-8576 C649 062
8311, 8312, 8316-8319, 8361 C000-C809 062
(c) Unspecified malignant renal tumors 8000-8005 C649 063
VII Hepatic tumors      
(a) Hepatoblastoma 8970 C000-C809 071
(b) Hepatic carcinomas 8010-8041, 8050-8075, 8082, 8120-8122, 8140, 8141, 8143, 8155, 8190-8201, 8210, 8211, 8230, 8231, 8240, 8241, 8244-8246, 8260-8264, 8310, 8320, 8323, 8401, 8430, 8440, 8480-8490, 8504, 8510, 8550, 8560-8576 C220, C221 072
8160-8180 C000-C809 072
(c) Unspecified malignant hepatic tumors 8000-8005 C220, C221 073
VIII Malignant bone tumors      
(a) Osteosarcomas 9180-9187, 9191-9195, 9200 C400-C419, C760-C768, C809 081
(b) Chondrosarcomas 9210, 9220, 9240 C400-C419, C760-C768, C809 082
9221, 9230, 9241-9243 C000-C809 082
(c) Ewing tumor and related sarcomas of bone 9260 C400-C419, C760-C768, C809 083
9363-9365 C400-C419 083
(d) Other specified malignant bone tumors 8810, 8811, 8823, 8830 C400-C419 084
8812, 9250, 9261, 9262, 9270-9275, 9280-9282, 9290, 9300-9302, 9310-9312, 9320-9322, 9330, 9340-9342, 9370-9372 C000-C809 084
(e) Unspecified malignant bone tumors 8000-8005, 8800, 8801, 8803-8805 C400-C419 085
IX Soft tissue and other extraosseous sarcomas      
(a)Rhabdomyosarcomas 8900-8905, 8910, 8912, 8920, 8991 C000-C809 091
(b) Fibrosarcomas, peripheral nerve sheath tumors, and other fibrous neoplasms 8810, 8811, 8813-8815, 8821, 8823, 8834-8835 C000-C399, C440-C768, C809 092
8820, 8822, 8824-8827, 9150, 9160, 9491, 9540-9571, 9580 C000-C809 092
(c) Kaposi sarcoma 9140 C000-C809 093
(d) Other specified soft tissue sarcomas 8587, 8710-8713, 8806, 8831-8833, 8836, 8840-8842, 8850-8858, 8860-8862, 8870, 8880, 8881, 8890-8898, 8921, 8982, 8990, 9040-9044, 9120-9125, 9130-9133, 9135, 9136, 9141, 9142, 9161, 9170-9175, 9231, 9251, 9252, 9373, 9581 C000-C809 094
8830 C000-C399, C440-C768, C809 094
8963 C000-C639, C659-C699, C739-C768, C809 094
9180, 9210, 9220, 9240 C490-C499 094
9260 C000-C399, C470-C759 094
9364 C000-C399, C470-C639, C659-C699, C739-C768, C809 094
9365 C000-C399, C470-C639, C659-C768, C809 094
(e) Unspecified soft tissue sarcomas 8800-8805 C000-C399, C440-C768, C809 095
X Germ cell tumors, trophoblastic tumors, and neoplasms of gonads      
(a) Intracranial and intraspinal germ cell tumors 9060-9065, 9070-9072, 9080-9085, 9100, 9101 C700-C729, C751-C753 101
(b) Malignant extracranial and extragonadal germ cell tumors 9060-9065, 9070-9072, 9080-9085, 9100-9105 C000-C559, C570-C619, C630-C699, C739-C750, C754-C768, C809 102
(c) Malignant gonadal germ cell tumors 9060-9065, 9070-9073, 9080-9085, 9090, 9091, 9100, 9101 C569, C620-C629 103
(d) Gonadal carcinomas 8010-8041, 8050-8075, 8082, 8120-8122, 8130-8141, 8143, 8190-8201, 8210, 8211, 8221-8241, 8244-8246, 8260-8263, 8290, 8310, 8313, 8320, 8323, 8380-8384, 8430, 8440, 8480-8490, 8504, 8510, 8550, 8560-8573, 9000, 9014, 9015 C569, C620-C629 104
8441-8444, 8450, 8451, 8460-8473 C000-C809 104
(e) Other and unspecified malignant gonadal tumors 8590-8671 C000-C809 105
8000-8005 C569, C620-C629 105
XI Other malignant epithelial neoplasms and malignant melanomas      
(a) Adrenocortical carcinomas 8370-8375 C000-C809 111
(b) Thyroid carcinomas 8010-8041, 8050-8075, 8082, 8120-8122, 8130-8141, 8190, 8200, 8201, 8211, 8230, 8231, 8244-8246, 8260-8263, 8290, 8310, 8320, 8323, 8430, 8440, 8480, 8481, 8510, 8560-8573 C739 112
8330-8337, 8340-8347, 8350 C000-C809 112
(c) Nasopharyngeal carcinomas 8010-8041, 8050-8075, 8082, 8083, 8120-8122, 8130-8141, 8190, 8200, 8201, 8211, 8230, 8231, 8244-8246, 8260-8263, 8290, 8310, 8320, 8323, 8430, 8440, 8480, 8481, 8500-8576 C110-C119 113
(d) Malignant melanomas 8720-8780, 8790 C000-C809 114
(e) Skin carcinomas 8010-8041, 8050-8075, 8078, 8082, 8090-8110, 8140, 8143, 8147, 8190, 8200, 8240, 8246, 8247, 8260, 8310, 8320, 8323, 8390-8420, 8430, 8480, 8542, 8560, 8570-8573, 8940, 8941 C440-C449 115
(f) Other and unspecified carcinomas 8010-8084, 8120-8157, 8190-8264, 8290, 8310, 8313-8315, 8320-8325, 8360, 8380-8384, 8430-8440, 8452-8454, 8480-8586, 8588-8589, 8940, 8941, 8983, 9000, 9010-9016, 9020, 9030 C000-C109, C129-C218, C239-C399, C480-C488, C500-C559, C570-C619, C630-C639, C659-C729, C750-C768, C809 116
XII Other and unspecified malignant neoplasms      
(a) Other specified malignant tumors 8930-8936, 8950, 8951, 8971-8981, 9050-9055, 9110 C000-C809 121
9363 C000-C399, C470-C759 121
(b) Other unspecified malignant tumors 8000-8005 C000-C218, C239-C399, C420-C559, C570-C619, C630-C639, C659-C699, C739-C750, C754-C809 122
Not Classified by ICCC or in situ     999

1. Steliarova-Foucher E, Stiller C, Lacour B, Kaatsch P. International Classification of Childhood Cancer, Third Edition. Cancer 2005;103:1457-67.

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