Transient abnormal myelopoiesis

This neoplasm is not reportable.
Transient abnormal myelopoiesis
ICD-O-3 Morphology
Effective 2001 and later
Not Reportable
This neoplasm is not reportable
Primary Site(s)
Alternate Names
Transient myeloproliferative disorder
Transient abnormal myelopoiesis (TAM) is a unique disorder of Down syndrome newborns that presents with clinical and morphologic findings indistinguishable from AML. The blasts have morphologic and immunologic features of megakaryocytic lineage. This is part of the myeloid proliferations with Down syndrome WHO group, which also includes myeloid leukemia associated with Down syndrome (see 9898/3).
Definitive Diagnostic Methods
This data item does not apply
Genetics Data
This data item does not apply
This data item does not apply
No treatments found
Corresponding ICD-9 Codes
238.79 Other lymphatic and hematopoietic tissues
Corresponding ICD-10 Codes
D46.7 Other myelodysplastic syndromes
Corresponding ICD-10-CM Codes (U.S. only)
D46.Z Other myelodysplastic syndrome (effective October 01, 2015)