Immunoglobulin deposition diseases

This disease is not reportable.
Name
Immunoglobulin deposition diseases
ICD-O-2 Morphology
9769/1
Effective 1992 - 2000
ICD-O-3 Morphology
9769/1
Effective 2001 and later
Reportable
This disease is not reportable
Primary Site(s)
See Abstractor Notes
Alternate Names
Heavy chain deposition disease (HCDD)
Light and heavy chain deposition disease (LHCDD)
Light chain deposition disease (LCDD)
Monoclonal immunoglobulin deposition disease (MIDD)
Primary amyloidosis
Randall disease
Systemic light chain disease
Definition
The monoclonal immunoglobulin deposition diseases are closely-related disorders that are characterized by visceral and soft tissue deposition of immunoglobulin, resulting in compromised organ function. The immunoglobulin molecule accumulates in tissue before the development of a large tumor burden.
Genetics Data
t(11;14)
Immunophenotyping
Amyloid P component
Treatments
Chemotherapy
Stem cell transplant
Corresponding ICD-9 Codes
238.79 Other lymphatic and hematopoietic tissues
Corresponding ICD-10 Codes
D47.9 Neoplasm of uncertain or unknown behavior of lymphoid, hematopoietic, and related tissue, unspecified
Corresponding ICD-10-CM Codes (effective October 1, 2015 U.S. only)
D47.Z9 Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue