Refractory neutropenia

Name
Refractory neutropenia
ICD-O-3 Morphology
9991/3
Effective 2010 and later
Reportable
for cases diagnosed 2010 and later
Primary Site(s)
C421

Help me code for dx year :

Grade
9 - Grade/differentiation unknown, not stated, or not applicable
Module Rule
None
Alternate Names
None
Definition
Refractory neutropenia is characterized by >=10% dysplastic neutrophils in the peripheral blood or bone marrow; the dysplasia is principally manifest as nuclear hypolobation and hypogranulation.
Abstractor Notes
(This code is effective for cases diagnosed 2010 and later. For cases diagnosed prior to 2010 see code 9989/3.) There will be >= 10% dysplastic neutrophils in the peripheral blood or bone marrow. Neutropenia secondary to drug therapy, toxic exposure, infectious processes, immune mechanisms, or other causative factors must be excluded. The other myeloid cell lines do not show significant dysplasia.
Definitive Diagnostic Methods
Bone marrow
Peripheral blood
Genetics Data
None
Immunophenotyping
None
Treatments
None
Transformations to
None
Transformations from
None
Corresponding ICD-9 Codes
238.72 Low grade myelodysplastic syndrome lesions
Corresponding ICD-10 Codes
D46.0 Refractory anemia without sideroblasts, so stated
Corresponding ICD-10-CM Codes (effective October 1, 2015 U.S. only)
D46.0 Refractory anemia without ring sideroblasts, so stated
Signs and Symptoms
None
Diagnostic Exams
None
Recurrence and Metastases
None
Epidemiology and Mortality
None