Refractory thrombocytopenia

Name
Refractory thrombocytopenia
ICD-O-3 Morphology
9992/3
Effective 2010 and later
Reportable
for cases diagnosed 2010 and later
Primary Site(s)
C421

Help me code for dx year :

Grade
9 - Grade/differentiation unknown, not stated, or not applicable
Module Rule
None
Alternate Names
RT
Definition
Refractory thrombocytopenia is characterized by >10% dysplastic megakaryocytes of at least 30 megakaryocytes.
Abstractor Notes
(This code is effective for cases diagnosed 2010 and later. For cases diagnosed prior to 2010 see code 9989/3.) Thrombocytopenia is an abnormal drop in the number of platelets which are involved in forming blood clots. Distinction between Refractory thrombocytopenia and other chronic autoimmune thrombocytopenia is critical and may be extremely difficult clinically and morphologically. Cytogenetic studies may be of considerable aid in this distinction. Cytogenetic abnormalities may be found in up to 50% of cases.
Definitive Diagnostic Methods
Clinical diagnosis
Genetics Data
Abnormalities of 5 and/or 6
del(20q), =8
Immunophenotyping
None
Treatments
No treatments found
Transformations from
None
Corresponding ICD-9 Codes
238.72 Low grade myelodysplastic syndrome lesions
Corresponding ICD-10 Codes
D46.0 Refractory anemia without sideroblasts, so stated
Corresponding ICD-10-CM Codes (effective October 1, 2015 U.S. only)
D46.0 Refractory anemia without ring sideroblasts, so stated
Signs and Symptoms
None
Diagnostic Exams
None
Recurrence and Metastases
None
Epidemiology and Mortality
None