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9 - Grade/differentiation unknown, not stated, or not applicable
This leukemia meets the criteria for MPAL in which the blasts also have t(9;22) translocation of BCR-ABL1 rearrangement. Some patients with chronic myeloidleukemia may develop or even present with a mixed blast phase that would meet criteria for MPAL; however, this diagnosis should not be made in patients known to have had CML.
(This code is effective for cases diagnosed 2010 and later. For cases diagnosed prior to 2010, see code 9801/3.)
Patients present with features similar to those of other patients with acute leukemia. Mixed phenotype acute leukemia (MPAL) diagnosis should not be made in patients known to have had CML.