Extraosseous plasmacytoma

Name
Extraosseous plasmacytoma
ICD-O-1 Morphology
9731/3
Effective 1978 - 1991
ICD-O-2 Morphology
9731/3
Effective 1992 - 2000
ICD-O-3 Morphology
9734/3
Effective 2001 and later
Reportable
for cases diagnosed 1978 and later
Primary Site(s)
See Abstractor Notes and Module 2 PH2

Help me code for dx year :

Grade
6 - B-cell
Module Rule
Module 2: PH2
Alternate Names
EMP
Extraosseous (extramedullary) plasmacytoma
Multiple extraosseous (extramedullary) plasmactyomas
Multiple plasmacytomas
Plasmacytoma, extramedullary
Definition
Plasmacytoma refers to a malignant monoclonal plasma cell tumor growing within soft tissue.

Clonal proliferation of plasma cells cytologically and immunophenotypically identical to those of plasma cell myeloma but forming tumors at extraosseous and extramedullary sites. 80% occur in upper respiratory tract, including oropharynx, nasopharynx, sinuses, larynx.
Abstractor Notes
Do not code primary site to C40._ or C41._. These category codes should only be used with histology 9731/3.

These plasmacytomas are localized plasma cell neoplasms that arise in tissues other than bone. Approximately 80% of extramedullary plasmacytomas occur in the upper respiratory tract including the oropharynx, nasopharynx, sinuses, and larynx. They may occur in numerous other sites including the gastrointestinal tract, lymph nodes, bladder, CNS, breast, thyroid, testis, parotid, and skin. 15% of upper respiratory plasmacytomas spread to the cervical lymph nodes. Radiology and bone marrow examination show no evidence of involvement. Do not code plasma cell myeloma/multiple myeloma (9732/3) just because there are multiple extraosseous plasmacytomas.

FISH and immunohistochemistry help to differentiate these lesions from MALT lymphoma.
Definitive Diagnostic Methods
FISH
Histology
Immunophenotyping
Genetics Data
Ig clonal rearrangements, complex karyotypes with multiple chromosomal gains/losses; also translocations, deletions, mutations
Immunophenotyping
Small M protein, most commonly IgA
Treatments
Chemotherapy
Radiation
Surgery
Transformations to
Transformations from
No Transformations
Same Primaries
None
Corresponding ICD-9 Codes
203.8 Other immunoproliferative neoplasms
Corresponding ICD-10 Codes
C90.2 Plasmacytoma, extramedullary
Corresponding ICD-10-CM Codes (effective October 1, 2015 U.S. only)
C90.2 Extramedullary plasmacytoma
Signs and Symptoms
None
Diagnostic Exams
None
Recurrence and Metastases
None
Epidemiology and Mortality
None