Statistics at a Glance

At a Glance

Estimated New Cases in 2023 59,610

% of All New Cancer Cases 3.0%

Estimated Deaths in 2023 23,710

% of All Cancer Deaths 3.9%

5-Year
Relative Survival

66.7% 2013–2019
Year Rate of New Cases — SEER 8 Rate of New Cases — SEER 12 Death Rate — U.S. 5-Year Relative Survival — SEER 8
Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend Observed Modeled Trend
1975 12.71 12.68 - - 8.09 8.19 33.36% 35.73%
1976 13.62 12.69 - - 8.10 8.18 33.14% 36.35%
1977 12.69 12.70 - - 8.11 8.16 37.10% 36.96%
1978 12.85 12.72 - - 8.02 8.14 37.69% 37.58%
1979 12.43 12.73 - - 8.26 8.13 33.68% 38.19%
1980 12.76 12.75 - - 8.36 8.11 37.98% 38.81%
1981 12.10 12.76 - - 8.10 8.09 36.80% 39.42%
1982 12.61 12.77 - - 8.19 8.08 36.74% 40.04%
1983 12.88 12.79 - - 8.11 8.06 38.26% 40.65%
1984 12.64 12.80 - - 8.08 8.05 38.53% 41.26%
1985 13.06 12.81 - - 8.07 8.03 42.52% 41.87%
1986 12.55 12.83 - - 7.96 8.01 41.88% 42.48%
1987 13.19 12.84 - - 7.80 8.00 42.67% 43.09%
1988 12.42 12.85 - - 7.83 7.98 44.06% 43.70%
1989 12.98 12.87 - - 7.95 7.97 45.14% 44.30%
1990 12.57 12.88 - - 7.98 7.95 44.97% 44.90%
1991 12.91 12.90 - - 7.99 7.93 44.70% 45.50%
1992 12.72 12.91 12.76 12.55 7.96 7.92 47.62% 46.10%
1993 12.85 12.92 12.76 12.63 7.93 7.90 47.00% 46.70%
1994 12.85 12.94 12.63 12.70 7.85 7.89 46.85% 47.29%
1995 13.57 12.95 13.38 12.78 7.90 7.87 49.28% 47.88%
1996 12.96 12.96 12.81 12.86 7.84 7.86 49.70% 48.47%
1997 13.06 12.98 12.91 12.94 7.71 7.79 49.10% 49.06%
1998 13.05 13.09 13.06 13.02 7.58 7.72 48.79% 49.64%
1999 12.69 13.21 12.47 13.10 7.68 7.66 48.97% 50.22%
2000 13.36 13.32 13.00 13.18 7.69 7.59 51.55% 52.21%
2001 14.27 13.44 13.60 13.26 7.64 7.53 55.59% 54.16%
2002 13.62 13.55 13.09 13.34 7.54 7.46 58.75% 56.06%
2003 13.78 13.67 13.32 13.42 7.45 7.40 58.07% 57.92%
2004 13.86 13.79 13.43 13.50 7.29 7.34 60.59% 59.73%
2005 13.72 13.91 13.23 13.59 7.26 7.27 62.62% 61.49%
2006 13.87 14.03 13.44 13.67 7.23 7.21 63.86% 63.20%
2007 13.74 14.15 13.57 13.75 7.08 7.15 64.98% 63.82%
2008 14.13 14.28 13.94 13.84 7.09 7.09 63.03% 64.44%
2009 14.10 14.40 13.93 13.92 7.06 7.03 64.39% 65.05%
2010 14.87 14.53 14.49 14.01 6.91 6.97 67.26% 65.65%
2011 14.95 14.65 14.28 14.09 6.95 6.91 68.58% 66.24%
2012 14.71 14.78 14.15 14.18 6.83 6.85 67.50% 66.83%
2013 14.88 14.91 14.22 14.27 6.76 6.71 68.28% 67.41%
2014 14.81 14.72 14.27 14.06 6.62 6.57 67.76% 67.98%
2015 14.19 14.52 13.57 13.86 6.29 6.43 70.91% 68.55%
2016 14.55 14.33 13.79 13.66 6.27 6.29 - 69.10%
2017 14.57 14.15 13.74 13.47 6.19 6.16 - 69.65%
2018 13.61 13.96 13.02 13.27 6.04 6.03 - 70.19%
2019 13.78 13.78 13.11 13.08 5.86 5.90 - 70.73%
2020 12.78 - 12.33 - 5.81 5.77 - 71.25%

New cases come from SEER 12. Deaths come from U.S. Mortality.
All Races, Both Sexes. Rates are Age-Adjusted.
Modeled trend lines were calculated from the underlying rates using the Joinpoint Trend Analysis Software.
The 2020 incidence rate is displayed but not used in the fit of the trend line(s). Impact of COVID on SEER Cancer Incidence 2020 data

New cases are also referred to as incident cases in other publications. Rates of new cases are also referred to as incidence rates.


Rate of New Cases and Deaths per 100,000: The rate of new cases of leukemia was 14.0 per 100,000 men and women per year. The death rate was 6.0 per 100,000 men and women per year. These rates are age-adjusted and based on 2016–2020 cases and deaths.

Lifetime Risk of Developing Cancer: Approximately 1.6 percent of men and women will be diagnosed with leukemia at some point during their lifetime, based on 2017–2019 data.

Prevalence of This Cancer: In 2020, there were an estimated 490,875 people living with leukemia in the United States.

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Survival Statistics

How Many People Survive 5 Years Or More after Being Diagnosed with Leukemia?

Relative survival is an estimate of the percentage of patients who would be expected to survive the effects of their cancer. It excludes the risk of dying from other causes. Because survival statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to treatment can vary greatly.

66.7%

5-Year
Relative Survival

66.7%

Based on data from SEER 22 (Excluding IL/MA) 2013–2019. Gray figures represent those who have died from leukemia. Green figures represent those who have survived 5 years or more.

New Cases and Deaths

How Common Is This Cancer?

Compared to other cancers, leukemia is relatively rare.

Rank Common Types of Cancer Estimated New
Cases 2023
Estimated
Deaths 2023
1. Breast Cancer (Female) 297,790 43,170
2. Prostate Cancer 288,300 34,700
3. Lung and Bronchus Cancer 238,340 127,070
4. Colorectal Cancer 153,020 52,550
5. Melanoma of the Skin 97,610 7,990
6. Bladder Cancer 82,290 16,710
7. Kidney and Renal Pelvis Cancer 81,800 14,890
8. Non-Hodgkin Lymphoma 80,550 20,180
9. Uterine Cancer 66,200 13,030
10. Pancreatic Cancer 64,050 50,550
- - -
11. Leukemia 59,610 23,710

Leukemia represents 3.0% of all new cancer cases in the U.S.

3.0%

In 2023, it is estimated that there will be 59,610 new cases of leukemia and an estimated 23,710 people will die of this disease.

Who Gets This Cancer?

Although leukemia is among the most common childhood cancers, it most often occurs in older adults. Leukemia is slightly more common in men than women. The rate of new cases of leukemia was 14.0 per 100,000 men and women per year based on 2016–2020 cases, age-adjusted.

Rate of New Cases per 100,000 Persons by Race/Ethnicity & Sex: Leukemia
Males
All Races 17.8
Hispanic 13.2
Non-Hispanic American Indian/Alaska Native 15.9
Non-Hispanic Asian/Pacific Islander 10.3
Non-Hispanic Black 13.7
Non-Hispanic White 19.6
Females
All Races 10.9
Hispanic 9.2
Non-Hispanic American Indian/Alaska Native 10.1
Non-Hispanic Asian/Pacific Islander 6.5
Non-Hispanic Black 9.2
Non-Hispanic White 11.7

SEER 22 2016–2020, Age-Adjusted

Percent of New Cases by Age Group: Leukemia
Age Range Percent of New Cases
<20 8.1%
20–34 4.3%
35–44 4.5%
45–54 8.7%
55–64 18.1%
65–74 25.2%
75–84 20.8%
>84 10.2%

Leukemia is most frequently diagnosed among people aged 65–74.

Median Age
At Diagnosis

67

SEER 22 2016–2020, All Races, Both Sexes

Who Dies From This Cancer?

Death rates from leukemia are higher among the elderly. People with leukemia have many treatment options, and treatment for leukemia can often control the disease and its symptoms. Leukemia is the seventh leading cause of cancer death in the United States. The death rate was 6.0 per 100,000 men and women per year based on 2016–2020 deaths, age-adjusted.

Death Rate per 100,000 Persons by Race/Ethnicity & Sex: Leukemia
Males
All Races 8.0
Hispanic 5.4
Non-Hispanic American Indian/Alaska Native 5.8
Non-Hispanic Asian/Pacific Islander 4.5
Non-Hispanic Black 6.8
Non-Hispanic White 8.6
Females
All Races 4.5
Hispanic 3.5
Non-Hispanic American Indian/Alaska Native 3.2
Non-Hispanic Asian/Pacific Islander 2.5
Non-Hispanic Black 4.3
Non-Hispanic White 4.7

U.S. 2016–2020, Age-Adjusted

Percent of Deaths by Age Group: Leukemia
Age Range Percent of Deaths
<20 1.9%
20–34 2.3%
35–44 2.3%
45–54 4.5%
55–64 11.9%
65–74 24.0%
75–84 30.4%
>84 22.7%

The percent of leukemia deaths is highest among people aged 75–84.

Median Age
At Death

76

U.S. 2016–2020, All Races, Both Sexes

Trends in Rates

Changes Over Time

Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments.

Using statistical models for analysis, age-adjusted rates for new leukemia cases have been falling on average 0.6% each year over 2010–2019. Age-adjusted death rates have been falling on average 2.0% each year over 2011–2020. 5-year relative survival trends are shown below.

Interactive Statistics with SEER*Explorer

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  • Create custom graphs and tables
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SEER*Explorer is an interactive website that provides easy access to a wide range of SEER cancer statistics. It provides detailed statistics for a cancer site by gender, race, calendar year, age, and for a selected number of cancer sites, by stage and histology.

Explore Additional Leukemia Statistics

More About This Cancer

Cancer and the Blood

Figure: Blood Cells Maturing from Stem Cells

Figure: Stem cells maturing into one of three types of mature blood cells: red blood cells, platelets, and white blood cells. Precursor cells are also shown: stem cells, myeloid blasts, lymphoid stem cells, and lymphoid blasts.

Leukemia is cancer that starts in the tissue that forms blood. Most blood cells develop from cells in the bone marrow called stem cells. In a person with leukemia, the bone marrow makes abnormal white blood cells. The abnormal cells are leukemia cells. Unlike normal blood cells, leukemia cells don't die when they should. They may crowd out normal white blood cells, red blood cells, and platelets. This makes it hard for normal blood cells to do their work. The four main types of leukemia are:

There is no standard staging system for leukemia. The disease is described as untreated, in remission, or recurrent.

Additional Information

Related Stat Facts by Subtype

More Information

Here are some resources for learning more about leukemia.

References

All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within SEER*Explorer.

Suggested Citation

All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.

SEER Cancer Stat Facts: Leukemia. National Cancer Institute. Bethesda, MD, https://seer.cancer.gov/statfacts/html/leuks.html

These stat facts focus on population statistics that are based on the U.S. population. Because these statistics are based on large groups of people, they cannot be used to predict exactly what will happen to an individual patient. To see tailored statistics, browse SEER*Explorer. To see statistics for a specific state, go to the State Cancer Profiles.

The statistics presented in these stat facts are based on the most recent data available, most of which can be found in SEER*Explorer. In some cases, different year spans may be used.

Estimates of new cases and deaths for 2023 are projections made by the American Cancer Society (ACS), based on earlier reported data.

Cancer is a complex topic. There is a wide range of information available. These stat facts do not address causes, symptoms, diagnosis, treatment, follow-up care, or decision making, although links are provided to information in many of these areas.