SEER*Rx Summary of Changes

August 2013 Release

A comprehensive review of the Federal Drug Administration (FDA) database for newly approved Hematology/Oncology drugs has been completed. Reviews of drugs approved January 1, 2012 to June 13, 2013 have been completed. Additional resources have been reviewed which resulted in the August 2013 update. No drugs have changed categories as a result of this update.

Summary Report

  • Total number of drugs listed in SEER*RX: 1834
  • Total number of Regimens listed in SEER*RX: 874
  • Number of drugs added: 9
  • Number of drugs modified: 20 (includes spelling and grammar corrects, updated remarks)
  • Number of regimens added: 21

New Drugs

Drug Name Category
Ado-trastuzumab emtansine BRM/Immunotherapy
Dabrafenib Chemotherapy
Gilotrif Chemotherapy
Ibrutinib Chemotherapy
Palbociclib Chemotherapy
Pomalidomide BRM/Immunotherapy
TACE procedure Definition/coding instructions
Trametinib Chemotherapy
Xofigo Radiation/radio-therapeutic drug

New Regimens

7+3
CB
CBI
CEPP
CFAR
CIM
CLAG-M
COI
FLO
FLOFIRI
FOLFOX
GEMOX-B
HDAC
ICE-V
LV5FU-P
MPV
OFF
PAD
R-MPV
TPC
VMPT

January 2013 Release

Important Update

A comprehensive review of chemotherapeutic drugs currently found in SEER*RX has been completed and in keeping with the FDA, the following drugs listed in the table below have changed categories from Chemotherapy to BRM/Immunotherapy. This change is effective with diagnosis date January 1, 2013 forward. For cases diagnosed prior to January 1, 2013 continue coding these six drugs as chemotherapy. Coding instructions related to this change have been added to the remarks field for the applicable drugs.

Drug Name(s) Previous Category New Category Effective Date
Alemtuzumab/Campath Chemotherapy BRM/Immuno 1/1/2013
Bevacizumab/Avastin Chemotherapy BRM/Immuno 1/1/2013
Rituximab Chemotherapy BRM/Immuno 1/1/2013
Trastuzumab/Herceptin Chemotherapy BRM/Immuno 1/1/2013
Pertuzumab/Perjeta Chemotherapy BRM/Immuno 1/1/2013
Cetuximab/Erbitux Chemotherapy BRM/Immuno 1/1/2013

Summary Report:

  • Total number of drugs listed in SEER*RX: 1825
  • Total number of Regimens listed in SEER*RX: 853
  • Number of drugs added: 12
  • Number of drugs modified: 71 (includes spelling and grammar corrections, updated remarks)
  • Number of regimens added: 3
  • Number of regimens deleted: 1 (duplicate)
  • Number of regimens modified: 255
    • When SEER*RX was moved to the new format, an ancillary drug, which is not coded, was inadvertently added to 255 regimens. The drug in question has been deleted from these regimens.